Unraveling the Health Effects of Environmental Mixtures: An NIEHS Priority

[...]unbiased approaches (i.e., approaches that provide comprehensive characterization of exposure without an a priori hypothesis) such as the exposome are needed to move beyond "looking under the lamppost" (i.e., only measuring exposure for chemicals with available toxicology data). [...]...

Full description

Saved in:
Bibliographic Details
Published inEnvironmental health perspectives Vol. 121; no. 1; pp. A6 - a8
Main Authors Carlin, Danielle J., Rider, Cynthia V., Woychik, Rick, Birnbaum, Linda S.
Format Journal Article
LanguageEnglish
Published United States National Institute of Environmental Health Sciences 01.01.2013
Subjects
Analysis
Chemical compounds
Chemicals
Collaboration
Conferences
Discipline
Environmental effects
Environmental Exposure
Environmental Health
Environmental protection
Epidemiology
Health aspects
Health risk assessment
Humans
Interdisciplinary aspects
Methods
National Institute of Environmental Health Sciences (U.S.)
Oil spills
Risk assessment
Science
Studies
Toxicology
United States
United States
Online AccessGet full text

Cover

More Information
Summary:[...]unbiased approaches (i.e., approaches that provide comprehensive characterization of exposure without an a priori hypothesis) such as the exposome are needed to move beyond "looking under the lamppost" (i.e., only measuring exposure for chemicals with available toxicology data). [...]participants in the NIEHS Mixtures Workshop discussed the importance of developing mixtures-related databases. Because it is challenging to search the literature for interactions among chemicals, there was a great deal of interest in the development of databases that would accommodate different levels of mixture study results (i.e., in vitro studies to human studies).
Bibliography:SourceType-Scholarly Journals-1
content type line 14
ObjectType-Editorial-2
ObjectType-Commentary-1
content type line 23
We thank C. Thompson, M. DeVito, and N. Walker for their guidance throughout the development of the NIEHS Mixtures Workshop. We also thank W. Suk for reviewing this editorial.
This editorial is the work product of an employee or group of employees of the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH); however, the statements, opinions, or conclusions contained therein do not necessarily represent the statements, opinions, or conclusions of NIEHS, NIH, or the United States government.
ISSN:0091-6765
1552-9924
1552-9924
DOI:10.1289/ehp.1206182