Effect of propranolol on gastric acid secretion in rats

The effect of propranolol, a beta-adrenoceptor blocking agent, has been investigated on gastric acid secretion in pylorus and cardiac-ligated rats. Compared to the control group, propranolol significantly diminished the gastric acid secretion, and inhibited the formation of gastric ulceration.

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Bibliographic Details
Published inBritish journal of pharmacology Vol. 46; no. 1; pp. 170 - 171
Main Authors Danhof, I. E., Geumei, Aida
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.09.1972
Subjects
Animals
Gastric Juice - metabolism
Male
Propranolol - pharmacology
Propranolol - therapeutic use
Rats
Secretory Rate - drug effects
Short Communications
Stomach Ulcer - prevention & control
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Summary:The effect of propranolol, a beta-adrenoceptor blocking agent, has been investigated on gastric acid secretion in pylorus and cardiac-ligated rats. Compared to the control group, propranolol significantly diminished the gastric acid secretion, and inhibited the formation of gastric ulceration.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-1188
1476-5381
DOI:10.1111/j.1476-5381.1972.tb06860.x