DGIdb: mining the druggable genome

A database of known drug-gene interactions, with information derived from many public sources, allows the identification of genes that are currently targeted by a drug and the membership of genes in a category, such as kinase genes, that have a high potential for drug development. The Drug-Gene Inte...

Full description

Saved in:
Bibliographic Details
Published inNature methods Vol. 10; no. 12; pp. 1209 - 1210
Main Authors Griffith, Malachi, Griffith, Obi L, Coffman, Adam C, Weible, James V, McMichael, Josh F, Spies, Nicholas C, Koval, James, Das, Indraniel, Callaway, Matthew B, Eldred, James M, Miller, Christopher A, Subramanian, Janakiraman, Govindan, Ramaswamy, Kumar, Runjun D, Bose, Ron, Ding, Li, Walker, Jason R, Larson, David E, Dooling, David J, Smith, Scott M, Ley, Timothy J, Mardis, Elaine R, Wilson, Richard K
Format Journal Article
LanguageEnglish
Published New York Nature Publishing Group US 01.12.2013
Nature Publishing Group
Subjects
631/114/129
631/114/2164
631/114/2401
631/154
Antineoplastic Agents - chemistry
Bioinformatics
Biological Microscopy
Biological Techniques
Biomedical Engineering/Biotechnology
Breast Neoplasms - drug therapy
Breast Neoplasms - genetics
brief-communication
Computational Biology - methods
Data Mining - methods
Databases, Genetic
Drug Discovery - methods
Drug Interactions
Drug therapy
Gene Expression Regulation - drug effects
Gene mutations
Genes
Genetic Variation
Genome
Genomes
Genomics
Genomics - methods
Humans
Information services
Life Sciences
Lung Neoplasms - drug therapy
Lung Neoplasms - genetics
Mines
Mutation
Online information services
Online services
Pharmaceutical research
Proteomics
Services
Software
Technology, Pharmaceutical - methods
United States
Online AccessGet full text

Cover

Abstract A database of known drug-gene interactions, with information derived from many public sources, allows the identification of genes that are currently targeted by a drug and the membership of genes in a category, such as kinase genes, that have a high potential for drug development. The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/ .
AbstractList The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/.
A database of known drug-gene interactions, with information derived from many public sources, allows the identification of genes that are currently targeted by a drug and the membership of genes in a category, such as kinase genes, that have a high potential for drug development. The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/ .
The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at
The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially druggable genes. DGIdb can be accessed at dgidb.org.
Audience Academic
Author Wilson, Richard K
Larson, David E
Smith, Scott M
McMichael, Josh F
Das, Indraniel
Griffith, Malachi
Govindan, Ramaswamy
Coffman, Adam C
Mardis, Elaine R
Callaway, Matthew B
Spies, Nicholas C
Bose, Ron
Ley, Timothy J
Weible, James V
Walker, Jason R
Dooling, David J
Koval, James
Kumar, Runjun D
Subramanian, Janakiraman
Griffith, Obi L
Eldred, James M
Ding, Li
Miller, Christopher A
AuthorAffiliation 1 The Genome Institute, Washington University School of Medicine, St. Louis, MO
2 Department of Genetics, Washington University School of Medicine, St. Louis, MO
4 Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO
3 Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
AuthorAffiliation_xml – name: 2 Department of Genetics, Washington University School of Medicine, St. Louis, MO
– name: 1 The Genome Institute, Washington University School of Medicine, St. Louis, MO
– name: 4 Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO
– name: 3 Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
Author_xml – sequence: 1
  givenname: Malachi
  orcidid: 0000-0002-6388-446X
  surname: Griffith
  fullname: Griffith, Malachi
  email: mgriffit@genome.wustl.edu
  organization: The Genome Institute, Washington University School of Medicine, Department of Genetics, Washington University School of Medicine
– sequence: 2
  givenname: Obi L
  surname: Griffith
  fullname: Griffith, Obi L
  email: ogriffit@genome.wustl.edu
  organization: The Genome Institute, Washington University School of Medicine, Department of Medicine, Division of Oncology, Washington University School of Medicine
– sequence: 3
  givenname: Adam C
  surname: Coffman
  fullname: Coffman, Adam C
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 4
  givenname: James V
  surname: Weible
  fullname: Weible, James V
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 5
  givenname: Josh F
  surname: McMichael
  fullname: McMichael, Josh F
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 6
  givenname: Nicholas C
  surname: Spies
  fullname: Spies, Nicholas C
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 7
  givenname: James
  surname: Koval
  fullname: Koval, James
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 8
  givenname: Indraniel
  surname: Das
  fullname: Das, Indraniel
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 9
  givenname: Matthew B
  surname: Callaway
  fullname: Callaway, Matthew B
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 10
  givenname: James M
  surname: Eldred
  fullname: Eldred, James M
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 11
  givenname: Christopher A
  surname: Miller
  fullname: Miller, Christopher A
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 12
  givenname: Janakiraman
  surname: Subramanian
  fullname: Subramanian, Janakiraman
  organization: Department of Medicine, Division of Oncology, Washington University School of Medicine
– sequence: 13
  givenname: Ramaswamy
  surname: Govindan
  fullname: Govindan, Ramaswamy
  organization: Department of Medicine, Division of Oncology, Washington University School of Medicine
– sequence: 14
  givenname: Runjun D
  surname: Kumar
  fullname: Kumar, Runjun D
  organization: Department of Medicine, Division of Oncology, Washington University School of Medicine
– sequence: 15
  givenname: Ron
  surname: Bose
  fullname: Bose, Ron
  organization: Department of Medicine, Division of Oncology, Washington University School of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine
– sequence: 16
  givenname: Li
  surname: Ding
  fullname: Ding, Li
  organization: The Genome Institute, Washington University School of Medicine, Department of Genetics, Washington University School of Medicine, Department of Medicine, Division of Oncology, Washington University School of Medicine
– sequence: 17
  givenname: Jason R
  surname: Walker
  fullname: Walker, Jason R
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 18
  givenname: David E
  surname: Larson
  fullname: Larson, David E
  organization: The Genome Institute, Washington University School of Medicine, Department of Genetics, Washington University School of Medicine
– sequence: 19
  givenname: David J
  surname: Dooling
  fullname: Dooling, David J
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 20
  givenname: Scott M
  surname: Smith
  fullname: Smith, Scott M
  organization: The Genome Institute, Washington University School of Medicine
– sequence: 21
  givenname: Timothy J
  surname: Ley
  fullname: Ley, Timothy J
  organization: The Genome Institute, Washington University School of Medicine, Department of Medicine, Division of Oncology, Washington University School of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine
– sequence: 22
  givenname: Elaine R
  surname: Mardis
  fullname: Mardis, Elaine R
  organization: The Genome Institute, Washington University School of Medicine, Department of Genetics, Washington University School of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine
– sequence: 23
  givenname: Richard K
  surname: Wilson
  fullname: Wilson, Richard K
  organization: The Genome Institute, Washington University School of Medicine, Department of Genetics, Washington University School of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine
BackLink https://www.ncbi.nlm.nih.gov/pubmed/24122041$$D View this record in MEDLINE/PubMed
BookMark eNptkUtLJDEUhYMovjf-gKEZN6J0m1Se5WJAHF8guNF1SKVuVUeqEiepEubfm572PSaLhHu_e8LJ2UKrPnhAaI_gGcFUHfsehvmsEKpcQZuEMzWVBPPV1zsuyQbaSukBY0pZwdfRRsFIUWBGNtHP35fXdXUy6Z13vp0Mc5jUcWxbU3UwacGHHnbQWmO6BLsv5za6vzi_O7ua3txeXp-d3kwtZ8UwBQBbFRawodBIYWxRS2ls2WCjsFKYEiVF3VTCGIFLLLhlklTMGNsYmat0G_1a6j6OVQ-1BT9E0-nH6HoT_-pgnP7c8W6u2_CkqeKEK5IFDl4EYvgzQhp075KFrjMewpg04UIoVjIqMrr_BX0IY_TZniZMcJwXIe9UazrQzjchv2sXovqUcio5ZZJmavYNlXcNvbM5qsbl-qeBw-WAjSGlCM2bR4L1IlH9L1G9SDTDPz7-yhv6GmEGjpZAyi3fQvxg5X-5Z-XPqtc
CitedBy_id crossref_primary_10_1038_ncomms15290
crossref_primary_10_1073_pnas_1517883113
crossref_primary_10_1038_s41598_017_10928_4
crossref_primary_10_1158_0008_5472_CAN_16_0436
crossref_primary_10_5483_BMBRep_2022_55_9_102
crossref_primary_10_3389_fgene_2019_00600
crossref_primary_10_1038_bcj_2015_24
crossref_primary_10_1002_cncr_28552
crossref_primary_10_1038_s41598_018_24005_x
crossref_primary_10_1161_CIRCGEN_117_001977
crossref_primary_10_15252_emmm_201708274
crossref_primary_10_1007_s13206_016_0308_3
crossref_primary_10_1186_s12920_017_0261_6
crossref_primary_10_2174_1574893618666230707123817
crossref_primary_10_1002_ijc_31140
crossref_primary_10_3389_fcvm_2022_1015473
crossref_primary_10_1186_s13058_014_0460_4
crossref_primary_10_1038_nm_3984
crossref_primary_10_1038_s41598_018_26453_x
crossref_primary_10_1007_s12031_020_01519_6
crossref_primary_10_5808_gi_22029
crossref_primary_10_3389_fonc_2017_00214
crossref_primary_10_1182_bloodadvances_2021004571
crossref_primary_10_1186_s12859_019_2811_8
crossref_primary_10_2174_1874205X01610010143
crossref_primary_10_18632_oncotarget_9370
crossref_primary_10_1134_S0026893323030160
crossref_primary_10_1007_s10029_020_02213_7
crossref_primary_10_1002_jcb_27825
crossref_primary_10_1038_s41467_021_27651_4
crossref_primary_10_1016_j_sjbs_2021_01_006
crossref_primary_10_1016_j_trsl_2024_05_008
crossref_primary_10_1038_s41419_021_04202_9
crossref_primary_10_1016_j_ejogrb_2020_05_026
crossref_primary_10_1002_art_42138
crossref_primary_10_3390_ijms19051461
crossref_primary_10_3109_00207454_2016_1149172
crossref_primary_10_1186_s13148_016_0240_3
crossref_primary_10_18632_oncotarget_21669
crossref_primary_10_1038_nature25169
crossref_primary_10_1016_j_tibs_2015_07_004
crossref_primary_10_3389_falgy_2021_738741
crossref_primary_10_1038_s41598_017_00122_x
crossref_primary_10_1016_j_tips_2017_08_006
crossref_primary_10_15252_msb_20177974
crossref_primary_10_3390_ph11020057
crossref_primary_10_1016_j_ygeno_2024_110834
crossref_primary_10_1016_j_compbiomed_2023_106656
crossref_primary_10_1093_nar_gkv1123
crossref_primary_10_1155_2022_5490461
crossref_primary_10_1007_s13721_018_0165_1
crossref_primary_10_1016_j_drudis_2018_11_002
crossref_primary_10_1101_mcs_a000752
crossref_primary_10_1007_s00439_020_02223_6
crossref_primary_10_1109_TCBB_2018_2835459
crossref_primary_10_1016_j_celrep_2016_09_079
crossref_primary_10_1016_j_imu_2022_101040
crossref_primary_10_3389_fonc_2021_692592
crossref_primary_10_2217_pgs_15_3
crossref_primary_10_1038_s41467_021_24813_2
crossref_primary_10_1182_bloodadvances_2022007250
crossref_primary_10_1002_ijc_29897
crossref_primary_10_1101_mcs_a005629
crossref_primary_10_1371_journal_pone_0238497
crossref_primary_10_3389_fneur_2021_610797
crossref_primary_10_1371_journal_pone_0254678
crossref_primary_10_1002_jcp_28172
crossref_primary_10_1038_ng_3838
crossref_primary_10_1093_database_bav097
crossref_primary_10_1016_j_compbiomed_2023_106544
crossref_primary_10_1093_bioinformatics_btz270
crossref_primary_10_1186_s12885_021_08293_7
crossref_primary_10_1371_journal_pcbi_1006730
crossref_primary_10_1016_j_exphem_2016_04_011
crossref_primary_10_2174_1386207325666220517110651
crossref_primary_10_1016_j_jad_2017_12_079
crossref_primary_10_1038_s41467_018_05914_x
crossref_primary_10_1016_j_bej_2023_109040
crossref_primary_10_1016_j_molcel_2015_05_008
crossref_primary_10_1109_JBHI_2019_2896144
crossref_primary_10_1073_pnas_1714877115
crossref_primary_10_1002_1878_0261_13057
crossref_primary_10_1371_journal_pone_0182999
crossref_primary_10_1007_s12033_024_01118_5
crossref_primary_10_1016_j_cmpb_2023_107864
crossref_primary_10_1161_ATVBAHA_115_306725
crossref_primary_10_1093_nar_gkaa1119
crossref_primary_10_2967_jnumed_117_198440
crossref_primary_10_1038_tpj_2015_32
crossref_primary_10_1016_j_jid_2018_08_030
crossref_primary_10_1093_g3journal_jkae040
crossref_primary_10_1002_mc_23419
crossref_primary_10_1016_j_molonc_2014_03_021
crossref_primary_10_1080_17460441_2016_1243524
crossref_primary_10_1161_CIRCGENETICS_116_001664
crossref_primary_10_1016_j_clbc_2020_04_005
crossref_primary_10_3390_ijms25137349
crossref_primary_10_1016_j_mrfmmm_2015_10_005
crossref_primary_10_1016_j_neurobiolaging_2022_12_012
crossref_primary_10_1089_omi_2023_0173
crossref_primary_10_1109_TCBB_2017_2765319
crossref_primary_10_1038_ni_2787
crossref_primary_10_1016_j_phrs_2019_104268
crossref_primary_10_15212_CVIA_2019_0588
crossref_primary_10_3389_fcvm_2022_900353
crossref_primary_10_1097_MD_0000000000007264
crossref_primary_10_1517_17460441_2015_1096926
crossref_primary_10_1016_j_cell_2015_11_062
crossref_primary_10_3390_ijms222111481
crossref_primary_10_1016_j_compbiolchem_2019_107139
crossref_primary_10_1002_jcla_24065
crossref_primary_10_1186_s12859_016_1065_y
crossref_primary_10_1016_j_jpba_2017_03_062
crossref_primary_10_1039_C6NP90016J
crossref_primary_10_1002_jsfa_12541
crossref_primary_10_3390_pathogens11020259
crossref_primary_10_1038_srep29228
crossref_primary_10_1016_j_ebiom_2023_104674
crossref_primary_10_1038_nbt_3183
crossref_primary_10_1038_s41593_018_0326_7
crossref_primary_10_1038_srep35228
crossref_primary_10_1038_nmeth_3505
crossref_primary_10_1038_s44321_024_00060_y
crossref_primary_10_1371_journal_pcbi_1003665
crossref_primary_10_1093_hmg_ddw160
crossref_primary_10_1016_j_jbi_2019_103224
crossref_primary_10_1038_s41398_019_0652_x
crossref_primary_10_1089_cmb_2019_0183
crossref_primary_10_1093_nar_gkv1165
crossref_primary_10_1002_pros_24050
crossref_primary_10_1371_journal_pcbi_1006266
crossref_primary_10_1371_journal_pone_0142443
crossref_primary_10_1038_s41467_023_38335_6
crossref_primary_10_1158_0008_5472_CAN_17_0341
crossref_primary_10_1016_j_cbpa_2017_04_012
crossref_primary_10_1038_s41467_020_15220_0
crossref_primary_10_1016_j_jksus_2021_101562
crossref_primary_10_18632_oncotarget_9636
crossref_primary_10_1016_j_physa_2017_01_059
crossref_primary_10_1080_23808993_2018_1467210
crossref_primary_10_1152_physiol_00008_2014
crossref_primary_10_1186_s13073_016_0390_0
crossref_primary_10_1371_journal_pone_0179037
crossref_primary_10_1016_j_jbi_2019_103238
crossref_primary_10_2217_cns_2019_0003
crossref_primary_10_1038_s41698_022_00257_9
crossref_primary_10_1186_s13073_017_0454_9
crossref_primary_10_1038_ncomms9019
crossref_primary_10_3892_etm_2018_6001
crossref_primary_10_1038_srep11966
crossref_primary_10_1093_bib_bbz157
crossref_primary_10_1158_0008_5472_CAN_23_3334
crossref_primary_10_1186_s12903_021_01827_2
crossref_primary_10_1371_journal_pone_0140359
crossref_primary_10_3389_fimmu_2022_1096587
crossref_primary_10_2147_DDDT_S417563
crossref_primary_10_1186_s13073_014_0064_8
crossref_primary_10_1016_j_ejmech_2014_10_038
crossref_primary_10_1038_mp_2015_28
crossref_primary_10_1038_s43587_023_00455_5
crossref_primary_10_1016_j_molmed_2016_04_001
crossref_primary_10_1186_1752_0509_9_S4_S2
crossref_primary_10_1186_s12918_019_0686_y
crossref_primary_10_3390_ph17070845
crossref_primary_10_1186_s13073_015_0240_5
crossref_primary_10_1371_journal_pone_0171413
crossref_primary_10_18632_oncotarget_25041
crossref_primary_10_3389_fimmu_2022_1030976
crossref_primary_10_1038_ng_3788
crossref_primary_10_1186_s40246_022_00381_4
crossref_primary_10_1080_07391102_2016_1157037
crossref_primary_10_1053_j_seminhematol_2014_08_006
crossref_primary_10_1182_bloodadvances_2020003443
crossref_primary_10_1534_genetics_117_300280
crossref_primary_10_1186_s12891_024_07349_6
crossref_primary_10_1007_s13353_024_00847_2
crossref_primary_10_1038_s41380_021_01335_3
crossref_primary_10_1038_srep36904
crossref_primary_10_1093_nar_gkw1102
crossref_primary_10_1038_ncomms15580
crossref_primary_10_1186_s12885_018_4345_2
crossref_primary_10_1186_s13073_018_0546_1
crossref_primary_10_1038_s41380_021_01104_2
crossref_primary_10_1038_s41569_020_00477_1
crossref_primary_10_1186_s13073_019_0687_x
crossref_primary_10_1016_j_neuron_2017_07_013
crossref_primary_10_3389_fgene_2021_698033
crossref_primary_10_1038_modpathol_2017_34
crossref_primary_10_1016_j_celrep_2020_107807
crossref_primary_10_1093_nar_gkx1143
crossref_primary_10_1186_s12967_023_04375_1
crossref_primary_10_1016_j_jbi_2021_103705
crossref_primary_10_1093_noajnl_vdaa151
crossref_primary_10_1016_j_urolonc_2016_05_012
crossref_primary_10_1016_j_ccell_2017_06_005
crossref_primary_10_1016_j_euf_2018_01_006
crossref_primary_10_3389_fcvm_2022_969421
crossref_primary_10_3390_cancers13143586
crossref_primary_10_1186_s13059_014_0438_7
crossref_primary_10_1016_j_lfs_2023_122388
crossref_primary_10_1038_s41598_021_93346_x
crossref_primary_10_1093_nargab_lqad032
crossref_primary_10_3389_fphar_2016_00449
crossref_primary_10_3390_pharmaceutics13040488
crossref_primary_10_7717_peerj_970
crossref_primary_10_18632_oncotarget_25981
crossref_primary_10_3109_10409238_2016_1173010
crossref_primary_10_1109_TPDS_2016_2620142
crossref_primary_10_1371_journal_pone_0143057
crossref_primary_10_1186_s40246_021_00341_4
crossref_primary_10_2174_1570159X16666180419124508
crossref_primary_10_1007_s00439_023_02627_0
crossref_primary_10_1186_s12859_021_04377_0
crossref_primary_10_1080_14787210_2022_1990756
crossref_primary_10_1016_j_atherosclerosis_2021_11_025
crossref_primary_10_1101_gr_221218_117
crossref_primary_10_1016_j_cels_2017_06_002
crossref_primary_10_1016_j_heliyon_2024_e34033
crossref_primary_10_1158_1078_0432_CCR_20_4004
crossref_primary_10_1038_s41525_022_00290_4
crossref_primary_10_1186_s12885_019_6462_y
crossref_primary_10_1002_ijc_34162
crossref_primary_10_1093_nar_gkad1040
crossref_primary_10_1371_journal_pcbi_1004274
crossref_primary_10_1186_s12885_016_2209_1
crossref_primary_10_1109_TCBB_2018_2829507
crossref_primary_10_1016_j_medidd_2020_100069
crossref_primary_10_1038_nature16478
crossref_primary_10_1002_wsbm_1364
crossref_primary_10_1101_mcs_a001677
crossref_primary_10_15406_mojpb_2014_01_00006
crossref_primary_10_1002_elps_201400022
crossref_primary_10_3390_ijms20092086
crossref_primary_10_1073_pnas_1705381114
crossref_primary_10_1093_hmg_ddw307
crossref_primary_10_18632_oncotarget_2374
crossref_primary_10_1016_j_ymeth_2023_12_001
crossref_primary_10_1038_s12276_022_00876_z
crossref_primary_10_1016_j_ccell_2023_03_007
crossref_primary_10_1002_pmic_201600234
crossref_primary_10_1007_s10142_014_0364_5
crossref_primary_10_1186_s12920_017_0311_0
crossref_primary_10_1038_s41467_024_47581_1
crossref_primary_10_1038_s41588_018_0102_3
crossref_primary_10_3389_fgene_2022_994163
crossref_primary_10_1371_journal_pcbi_1006639
crossref_primary_10_1093_jamia_ocw007
crossref_primary_10_1186_s12885_015_1077_4
crossref_primary_10_1038_s41588_018_0151_7
crossref_primary_10_1038_s42003_019_0736_4
crossref_primary_10_1016_j_molonc_2016_08_003
crossref_primary_10_1186_s12885_019_5290_4
crossref_primary_10_1158_1541_7786_MCR_18_0946
crossref_primary_10_1093_bib_bbx169
crossref_primary_10_1186_s13073_018_0564_z
crossref_primary_10_1016_j_celrep_2018_09_031
crossref_primary_10_1016_j_ddmod_2017_07_004
crossref_primary_10_3233_IDA_215745
crossref_primary_10_5812_rro_142195
crossref_primary_10_1016_j_sjbs_2021_07_068
crossref_primary_10_1093_bioinformatics_bty913
crossref_primary_10_1038_s41573_019_0046_z
crossref_primary_10_7554_eLife_46793
crossref_primary_10_1016_j_xhgg_2022_100100
crossref_primary_10_1109_TCBB_2020_3031696
crossref_primary_10_1186_s12881_015_0262_2
crossref_primary_10_18632_oncotarget_9334
crossref_primary_10_1007_s13721_023_00440_3
crossref_primary_10_1038_s41467_018_06132_1
crossref_primary_10_3389_fmolb_2023_1200354
crossref_primary_10_1002_cam4_360
crossref_primary_10_1038_s41467_022_28378_6
crossref_primary_10_1093_nar_gkaa1084
crossref_primary_10_1186_s13073_014_0115_1
crossref_primary_10_1016_j_gpb_2018_10_006
crossref_primary_10_1093_schbul_sbv170
crossref_primary_10_3389_fimmu_2023_1186097
crossref_primary_10_1002_wsbm_1290
crossref_primary_10_1080_21623945_2021_2013406
crossref_primary_10_1016_j_celrep_2022_111153
crossref_primary_10_1186_1471_2105_15_S11_S3
crossref_primary_10_1186_s12916_021_02186_z
crossref_primary_10_1371_journal_pone_0247612
crossref_primary_10_1080_15384101_2016_1198862
crossref_primary_10_1007_s40120_019_0131_6
crossref_primary_10_1093_bib_bbw059
crossref_primary_10_18632_oncotarget_5543
crossref_primary_10_1093_bib_bbad137
crossref_primary_10_1038_s41588_018_0209_6
crossref_primary_10_1186_1471_2105_15_S11_S9
crossref_primary_10_1158_1541_7786_MCR_18_1335
crossref_primary_10_1126_scitranslmed_aaw7852
crossref_primary_10_1016_j_tube_2024_102538
crossref_primary_10_1016_j_surg_2016_06_064
crossref_primary_10_2174_0929867326666190808154841
crossref_primary_10_3390_v8100269
crossref_primary_10_1515_jib_2023_0011
crossref_primary_10_3390_ijms20081962
crossref_primary_10_1038_s41573_021_00245_x
crossref_primary_10_1002_mds_26075
crossref_primary_10_1038_s41588_018_0176_y
crossref_primary_10_1186_s13045_017_0465_4
crossref_primary_10_1007_s13721_022_00371_5
crossref_primary_10_1080_07853890_2021_1966087
crossref_primary_10_3389_fphar_2019_00561
crossref_primary_10_1016_j_celrep_2021_110100
crossref_primary_10_1038_s41388_021_01882_7
crossref_primary_10_1016_j_esmoop_2022_100570
crossref_primary_10_1021_acssynbio_8b00237
crossref_primary_10_1186_s12859_016_1010_0
crossref_primary_10_1186_s13059_014_0485_0
crossref_primary_10_1016_j_tem_2018_11_005
crossref_primary_10_1038_s41598_022_13159_4
crossref_primary_10_1093_bib_bbab180
crossref_primary_10_1093_hmg_ddab102
crossref_primary_10_2217_pgs_2016_0152
crossref_primary_10_1210_js_2018_00113
crossref_primary_10_1186_s12911_018_0680_0
crossref_primary_10_3892_mmr_2016_6058
crossref_primary_10_1126_scisignal_abb0619
crossref_primary_10_3389_fendo_2022_942368
crossref_primary_10_3389_fimmu_2023_1179664
crossref_primary_10_1038_s41589_018_0205_2
crossref_primary_10_7717_peerj_9294
crossref_primary_10_1002_ijc_30726
crossref_primary_10_1021_cb5001839
crossref_primary_10_4137_CIN_S31809
crossref_primary_10_3389_fimmu_2017_00918
crossref_primary_10_1016_j_molcel_2016_06_022
crossref_primary_10_3390_metabo10050202
crossref_primary_10_1007_s11357_022_00704_2
crossref_primary_10_3389_fgene_2020_00393
crossref_primary_10_1038_s41467_023_42233_2
crossref_primary_10_1073_pnas_1422640112
crossref_primary_10_1186_s13073_016_0384_y
crossref_primary_10_1093_biolre_ioab172
crossref_primary_10_3390_genes12121898
crossref_primary_10_1016_j_jmoldx_2015_05_002
Cites_doi 10.1093/nar/gkq1237
10.1038/nrd892
10.1038/nature11017
10.1093/nar/gkp1014
10.1038/nature09208
10.1038/75556
10.1038/nature11412
10.1517/14728222.8.6.587
10.1093/nar/gkl999
10.1093/nar/gkq1037
10.1016/S1359-6446(05)03666-4
10.1097/01.JTO.0000407557.30793.a6
10.1038/nature11154
10.1186/1471-2105-9-104
10.1093/nar/gks994
10.2217/bmm.11.94
10.1158/1078-0432.CCR-12-1894
10.1038/msb.2009.98
10.1093/nar/gkq1126
10.1038/nrd3478
10.1093/nar/gkp934
10.1093/nar/gkr1011
10.1093/nar/gks1111
10.1093/nar/gkq1064
10.1093/nar/gkr1132
10.1038/nature10933
10.1126/science.1132939
10.1371/journal.pone.0067980
10.1093/nar/gkp970
10.1038/nature11159
10.1093/nar/gkr948
10.1158/2159-8290.CD-12-0349
10.1093/nar/gkr1065
10.1126/science.1075762
10.1093/nar/gkr912
10.1038/nature11003
10.1093/nar/gkr777
ContentType Journal Article
Copyright Springer Nature America, Inc. 2013
COPYRIGHT 2013 Nature Publishing Group
Copyright Nature Publishing Group Dec 2013
Copyright_xml – notice: Springer Nature America, Inc. 2013
– notice: COPYRIGHT 2013 Nature Publishing Group
– notice: Copyright Nature Publishing Group Dec 2013
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
3V.
7QL
7QO
7SS
7TK
7U9
7X2
7X7
7XB
88E
88I
8AO
8FD
8FE
8FG
8FH
8FI
8FJ
8FK
ABJCF
ABUWG
AFKRA
ARAPS
ATCPS
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
BKSAR
C1K
CCPQU
D1I
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
H94
HCIFZ
K9.
KB.
L6V
LK8
M0K
M0S
M1P
M2P
M7N
M7P
M7S
P5Z
P62
P64
PATMY
PCBAR
PDBOC
PQEST
PQQKQ
PQUKI
PTHSS
PYCSY
Q9U
RC3
5PM
DOI 10.1038/nmeth.2689
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
ProQuest Central (Corporate)
Bacteriology Abstracts (Microbiology B)
Biotechnology Research Abstracts
Entomology Abstracts (Full archive)
Neurosciences Abstracts
Virology and AIDS Abstracts
Agricultural Science Collection
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Science Database (Alumni Edition)
ProQuest Pharma Collection
Technology Research Database
ProQuest SciTech Collection
ProQuest Technology Collection
ProQuest Natural Science Collection
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
Materials Science & Engineering Collection
ProQuest Central (Alumni)
ProQuest Central
Advanced Technologies & Aerospace Collection
Agricultural & Environmental Science Collection
ProQuest Central Essentials
Biological Science Collection
ProQuest Central
Technology Collection
ProQuest Natural Science Collection
Earth, Atmospheric & Aquatic Science Collection
Environmental Sciences and Pollution Management
ProQuest One Community College
ProQuest Materials Science Collection
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
AIDS and Cancer Research Abstracts
SciTech Premium Collection
ProQuest Health & Medical Complete (Alumni)
Materials Science Database
ProQuest Engineering Collection
ProQuest Biological Science Collection
Agriculture Science Database
Health & Medical Collection (Alumni Edition)
Medical Database
Science Database
Algology Mycology and Protozoology Abstracts (Microbiology C)
Biological Science Database
Engineering Database
Advanced Technologies & Aerospace Database
ProQuest Advanced Technologies & Aerospace Collection
Biotechnology and BioEngineering Abstracts
Environmental Science Database
Earth, Atmospheric & Aquatic Science Database
Materials Science Collection
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
Engineering Collection
Environmental Science Collection
ProQuest Central Basic
Genetics Abstracts
PubMed Central (Full Participant titles)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
Agricultural Science Database
ProQuest Central Student
ProQuest Advanced Technologies & Aerospace Collection
ProQuest Central Essentials
SciTech Premium Collection
Environmental Sciences and Pollution Management
Health Research Premium Collection
Natural Science Collection
Biological Science Collection
ProQuest Medical Library (Alumni)
Engineering Collection
Advanced Technologies & Aerospace Collection
Engineering Database
Virology and AIDS Abstracts
ProQuest Science Journals (Alumni Edition)
ProQuest Biological Science Collection
ProQuest One Academic Eastern Edition
Earth, Atmospheric & Aquatic Science Database
Agricultural Science Collection
ProQuest Hospital Collection
ProQuest Technology Collection
Health Research Premium Collection (Alumni)
Biological Science Database
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Environmental Science Collection
Entomology Abstracts
ProQuest Health & Medical Complete
ProQuest One Academic UKI Edition
Environmental Science Database
Engineering Research Database
ProQuest One Academic
Technology Collection
Technology Research Database
Materials Science Collection
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest Natural Science Collection
ProQuest Pharma Collection
ProQuest Central
Earth, Atmospheric & Aquatic Science Collection
Genetics Abstracts
ProQuest Engineering Collection
Biotechnology Research Abstracts
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Bacteriology Abstracts (Microbiology B)
Algology Mycology and Protozoology Abstracts (Microbiology C)
Agricultural & Environmental Science Collection
AIDS and Cancer Research Abstracts
Materials Science Database
ProQuest Materials Science Collection
ProQuest Central Basic
ProQuest Science Journals
ProQuest SciTech Collection
Advanced Technologies & Aerospace Database
ProQuest Medical Library
Materials Science & Engineering Collection
ProQuest Central (Alumni)
DatabaseTitleList MEDLINE


Genetics Abstracts

Agricultural Science Database
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: 8FG
  name: ProQuest Technology Collection
  url: https://search.proquest.com/technologycollection1
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Biology
EISSN 1548-7105
EndPage 1210
ExternalDocumentID 3146353131
A353753473
10_1038_nmeth_2689
24122041
Genre Journal Article
GeographicLocations United States
GeographicLocations_xml – name: United States
GrantInformation_xml – fundername: NCI NIH HHS
  grantid: P01 CA101937
– fundername: NHGRI NIH HHS
  grantid: U54 HG003079
GroupedDBID ---
-~X
0R~
123
29M
39C
3V.
4.4
53G
5BI
7X2
7X7
7XC
88E
88I
8AO
8CJ
8FE
8FG
8FH
8FI
8FJ
8R4
8R5
AAEEF
AAHBH
AARCD
AAZLF
ABAWZ
ABDBF
ABJCF
ABJNI
ABLJU
ABUWG
ABVXF
ACGFS
ACGOD
ACIWK
ACPRK
ADBBV
AENEX
AFBBN
AFKRA
AFRAH
AFSHS
AGAYW
AGEZK
AHBCP
AHMBA
AHSBF
AIBTJ
ALFFA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
ARAPS
ARMCB
ASPBG
ATCPS
AVWKF
AXYYD
AZFZN
AZQEC
BBNVY
BENPR
BGLVJ
BHPHI
BKKNO
BKSAR
BPHCQ
BVXVI
CCPQU
CS3
D1I
D1J
D1K
DB5
DU5
DWQXO
EBS
EE.
EJD
EMOBN
ESX
F5P
FEDTE
FSGXE
FYUFA
FZEXT
GNUQQ
HCIFZ
HMCUK
HVGLF
HZ~
IAO
IHR
INH
INR
ITC
K6-
KB.
L6V
LK5
LK8
M0K
M1P
M2P
M7P
M7R
M7S
NNMJJ
O9-
ODYON
P2P
P62
PATMY
PCBAR
PDBOC
PQQKQ
PROAC
PSQYO
PTHSS
PYCSY
Q2X
RNS
RNT
RNTTT
SHXYY
SIXXV
SJN
SNYQT
SV3
TAOOD
TBHMF
TDRGL
TSG
TUS
UKHRP
~8M
AAYZH
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
AADEA
ABEEJ
ABGIJ
ACBMV
ACBRV
ACBYP
ACIGE
ACTTH
ACVWB
ADMDM
ADQMX
ADZGE
AEDAW
AEFTE
AGGBP
AHGBK
AJDOV
ZA5
FIGPU
7QL
7QO
7SS
7TK
7U9
7XB
8FD
8FK
C1K
FR3
H94
K9.
M7N
P64
PQEST
PQUKI
Q9U
RC3
5PM
ID FETCH-LOGICAL-c542t-eeecb2ce0a3ef76ac2d77ac9f0a8088031876dfb6aa609065c471b4aacfa7b6a3
IEDL.DBID BENPR
ISSN 1548-7091
IngestDate Tue Sep 17 21:14:21 EDT 2024
Fri Aug 16 21:28:43 EDT 2024
Thu Oct 10 21:12:09 EDT 2024
Fri Feb 23 00:11:01 EST 2024
Fri Feb 02 04:27:07 EST 2024
Thu Sep 12 16:31:48 EDT 2024
Tue Oct 15 23:46:42 EDT 2024
Fri Oct 11 20:36:57 EDT 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 12
Language English
License Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c542t-eeecb2ce0a3ef76ac2d77ac9f0a8088031876dfb6aa609065c471b4aacfa7b6a3
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
These authors contributed equally to this work.
ORCID 0000-0002-6388-446X
000000026388446X
OpenAccessLink https://pubmed.ncbi.nlm.nih.gov/PMC3851581
PMID 24122041
PQID 1465000011
PQPubID 28015
PageCount 2
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_3851581
proquest_miscellaneous_1566849436
proquest_journals_1465000011
gale_infotracmisc_A353753473
gale_infotracacademiconefile_A353753473
crossref_primary_10_1038_nmeth_2689
pubmed_primary_24122041
springer_journals_10_1038_nmeth_2689
PublicationCentury 2000
PublicationDate 2013-12-01
PublicationDateYYYYMMDD 2013-12-01
PublicationDate_xml – month: 12
  year: 2013
  text: 2013-12-01
  day: 01
PublicationDecade 2010
PublicationPlace New York
PublicationPlace_xml – name: New York
– name: United States
PublicationSubtitle Techniques for life scientists and chemists
PublicationTitle Nature methods
PublicationTitleAbbrev Nat Methods
PublicationTitleAlternate Nat Methods
PublicationYear 2013
Publisher Nature Publishing Group US
Nature Publishing Group
Publisher_xml – name: Nature Publishing Group US
– name: Nature Publishing Group
References KuhnMCampillosMLetunicIJensenLJBorkPMol. Syst. Biol.2010634310.1038/msb.2009.98
FlicekPNucleic Acids Res.201139D800D8061:CAS:528:DC%2BC3sXivF2lsro%3D10.1093/nar/gkq1064
LambJScience2006313192919351:CAS:528:DC%2BD28XhtVSnsrbN10.1126/science.1132939
KnoxCNucleic Acids Res.201139D1035D10411:CAS:528:DC%2BC3sXivF2mtrg%3D10.1093/nar/gkq1126
GaoZBMC Bioinformatics2008910410.1186/1471-2105-9-104
BarretinaJNature20124836036071:CAS:528:DC%2BC38XmtVequ7o%3D10.1038/nature11003
Rask-AndersenMAlmenMSSchiothHBNat. Rev. Drug Discov.2011105795901:CAS:528:DC%2BC3MXpsFKqsLc%3D10.1038/nrd3478
PuntaMNucleic Acids Res.201240D290D3011:CAS:528:DC%2BC3MXhs12hurvK10.1093/nar/gkr1065
LounkineENature20124863613671:CAS:528:DC%2BC38XovFyrtb0%3D10.1038/nature11159
ZhuFNucleic Acids Res.201038D787D7911:CAS:528:DC%2BC3cXktlymtg%3D%3D10.1093/nar/gkp1014
OrthAPBatalovSPerroneMChandaSKExpert Opin. Ther. Targets200485875961:CAS:528:DC%2BD2MXmt1eisA%3D%3D10.1517/14728222.8.6.587
AshburnerMNat. Genet.20002525291:CAS:528:DC%2BD3cXjtFSlsbc%3D10.1038/75556
YehPClin. Cancer Res.201319189419011:CAS:528:DC%2BC3sXlsVCmsbk%3D10.1158/1078-0432.CCR-12-1894
YangWNucleic Acids Res.201341D955D9611:CAS:528:DC%2BC38XhvV2ksbbJ10.1093/nar/gks1111
SomaiahNSimonGRJ. Thorac. Oncol.20116S1758S178510.1097/01.JTO.0000407557.30793.a6
von EichbornJNucleic Acids Res.201139D1060D10661:CAS:528:DC%2BC3sXivF2ltb0%3D10.1093/nar/gkq1037
LiuTLinYWenXJorissenRNGilsonMKNucleic Acids Res.200735D198D2011:CAS:528:DC%2BD2sXivFKktg%3D%3D10.1093/nar/gkl999
BanerjiSNature20124864054091:CAS:528:DC%2BC38XovFykur8%3D10.1038/nature11154
WangYNucleic Acids Res.201240D400D4121:CAS:528:DC%2BC3MXhs12hurzI10.1093/nar/gkr1132
KanZNature20104668698731:CAS:528:DC%2BC3cXptl2rs7s%3D10.1038/nature09208
KuhnMNucleic Acids Res.201240D876D8801:CAS:528:DC%2BC3MXhs12hur3I10.1093/nar/gkr1011
RussAPLampelSDrug Discov. Today2005101607161010.1016/S1359-6446(05)03666-4
HeckerNNucleic Acids Res.201240D1113D11171:CAS:528:DC%2BC3MXhs12hurbI10.1093/nar/gkr912
DavisAPNucleic Acids Res.201341D1104D11141:CAS:528:DC%2BC38XhvV2ksbvO10.1093/nar/gks994
PreissnerSNucleic Acids Res.201038D237D2431:CAS:528:DC%2BC3cXktlGquw%3D%3D10.1093/nar/gkp970
ShahSPNature20124863953991:CAS:528:DC%2BC38XmtVersL4%3D10.1038/nature10933
HopkinsALGroomCRNat. Rev. Drug Discov.200217277301:CAS:528:DC%2BD38XmslamtrY%3D10.1038/nrd892
LimENucleic Acids Res.201038D781D7861:CAS:528:DC%2BC3cXktlyktw%3D%3D10.1093/nar/gkp934
McDonaghEMWhirl-CarrilloMGartenYAltmanRBKleinTEBiomarkers Med.201157958061:CAS:528:DC%2BC3MXhsFamtrbL10.2217/bmm.11.94
ManningGWhyteDBMartinezRHunterTSudarsanamSScience2002298191219341:CAS:528:DC%2BD38Xpt1Wisb0%3D10.1126/science.1075762
Cancer Genome Atlas Network. Nature490, 61–70 (2012).
HunterSNucleic Acids Res.201240D306D3121:CAS:528:DC%2BC3MXhs12hurfO10.1093/nar/gkr948
GaultonANucleic Acids Res.201240D1100D11071:CAS:528:DC%2BC3MXhs12htbjN10.1093/nar/gkr777
StephensPJNature20124864004041:CAS:528:DC%2BC38XovFyrsrs%3D10.1038/nature11017
KumarRDChangLWEllisMJBoseRPLoS One20138e679801:CAS:528:DC%2BC3sXhtFahsrzF10.1371/journal.pone.0067980
MaglottDOstellJPruittKDTatusovaTNucleic Acids Res.201139D52D571:CAS:528:DC%2BC3sXivF2ltbc%3D10.1093/nar/gkq1237
BoseRCancer Discov.201332242371:CAS:528:DC%2BC3sXis1Wktrg%3D10.1158/2159-8290.CD-12-0349
12471243 - Science. 2002 Dec 6;298(5600):1912-34
12209152 - Nat Rev Drug Discov. 2002 Sep;1(9):727-30
22140110 - Nucleic Acids Res. 2012 Jan;40(Database issue):D400-12
22495314 - Nature. 2012 Jun 21;486(7403):395-9
15584864 - Expert Opin Ther Targets. 2004 Dec;8(6):587-96
17008526 - Science. 2006 Sep 29;313(5795):1929-35
16376820 - Drug Discov Today. 2005 Dec;10(23-24):1607-10
22722194 - Nature. 2012 Jun 21;486(7403):361-7
21115458 - Nucleic Acids Res. 2011 Jan;39(Database issue):D52-7
22460905 - Nature. 2012 Mar 29;483(7391):603-7
22005529 - J Thorac Oncol. 2011 Nov;6(11 Suppl 4):S1758-85
23220880 - Cancer Discov. 2013 Feb;3(2):224-37
21948594 - Nucleic Acids Res. 2012 Jan;40(Database issue):D1100-7
21071407 - Nucleic Acids Res. 2011 Jan;39(Database issue):D1060-6
21045057 - Nucleic Acids Res. 2011 Jan;39(Database issue):D800-6
20087340 - Mol Syst Biol. 2010;6:343
22075997 - Nucleic Acids Res. 2012 Jan;40(Database issue):D876-80
22127870 - Nucleic Acids Res. 2012 Jan;40(Database issue):D290-301
22103613 - Biomark Med. 2011 Dec;5(6):795-806
18282303 - BMC Bioinformatics. 2008;9:104
23180760 - Nucleic Acids Res. 2013 Jan;41(Database issue):D955-61
19934256 - Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43
22722201 - Nature. 2012 Jun 21;486(7403):400-4
19933260 - Nucleic Acids Res. 2010 Jan;38(Database issue):D787-91
22096229 - Nucleic Acids Res. 2012 Jan;40(Database issue):D306-12
10802651 - Nat Genet. 2000 May;25(1):25-9
21804595 - Nat Rev Drug Discov. 2011 Aug;10(8):579-90
19897546 - Nucleic Acids Res. 2010 Jan;38(Database issue):D781-6
23826350 - PLoS One. 2013 Jun 27;8(6):e67980
23000897 - Nature. 2012 Oct 4;490(7418):61-70
20668451 - Nature. 2010 Aug 12;466(7308):869-73
17145705 - Nucleic Acids Res. 2007 Jan;35(Database issue):D198-201
22067455 - Nucleic Acids Res. 2012 Jan;40(Database issue):D1113-7
23093600 - Nucleic Acids Res. 2013 Jan;41(Database issue):D1104-14
21059682 - Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41
22722202 - Nature. 2012 Jun 21;486(7403):405-9
BFnmeth2689_CR14
E Lim (BFnmeth2689_CR34) 2010; 38
SP Shah (BFnmeth2689_CR16) 2012; 486
S Preissner (BFnmeth2689_CR35) 2010; 38
M Kuhn (BFnmeth2689_CR36) 2010; 6
S Banerji (BFnmeth2689_CR13) 2012; 486
AP Russ (BFnmeth2689_CR2) 2005; 10
P Yeh (BFnmeth2689_CR19) 2013; 19
A Gaulton (BFnmeth2689_CR24) 2012; 40
M Rask-Andersen (BFnmeth2689_CR9) 2011; 10
P Flicek (BFnmeth2689_CR3) 2011; 39
R Bose (BFnmeth2689_CR18) 2013; 3
N Somaiah (BFnmeth2689_CR8) 2011; 6
AP Orth (BFnmeth2689_CR29) 2004; 8
PJ Stephens (BFnmeth2689_CR17) 2012; 486
E Lounkine (BFnmeth2689_CR37) 2012; 486
AL Hopkins (BFnmeth2689_CR1) 2002; 1
M Kuhn (BFnmeth2689_CR22) 2012; 40
AP Davis (BFnmeth2689_CR26) 2013; 41
M Punta (BFnmeth2689_CR21) 2012; 40
J Barretina (BFnmeth2689_CR33) 2012; 483
C Knox (BFnmeth2689_CR6) 2011; 39
RD Kumar (BFnmeth2689_CR12) 2013; 8
EM McDonagh (BFnmeth2689_CR7) 2011; 5
Z Kan (BFnmeth2689_CR15) 2010; 466
S Hunter (BFnmeth2689_CR20) 2012; 40
N Hecker (BFnmeth2689_CR23) 2012; 40
Z Gao (BFnmeth2689_CR27) 2008; 9
J Lamb (BFnmeth2689_CR30) 2006; 313
J von Eichborn (BFnmeth2689_CR25) 2011; 39
F Zhu (BFnmeth2689_CR10) 2010; 38
M Ashburner (BFnmeth2689_CR11) 2000; 25
T Liu (BFnmeth2689_CR31) 2007; 35
Y Wang (BFnmeth2689_CR5) 2012; 40
G Manning (BFnmeth2689_CR28) 2002; 298
W Yang (BFnmeth2689_CR32) 2013; 41
D Maglott (BFnmeth2689_CR4) 2011; 39
References_xml – volume: 39
  start-page: D52
  year: 2011
  ident: BFnmeth2689_CR4
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkq1237
  contributor:
    fullname: D Maglott
– volume: 1
  start-page: 727
  year: 2002
  ident: BFnmeth2689_CR1
  publication-title: Nat. Rev. Drug Discov.
  doi: 10.1038/nrd892
  contributor:
    fullname: AL Hopkins
– volume: 486
  start-page: 400
  year: 2012
  ident: BFnmeth2689_CR17
  publication-title: Nature
  doi: 10.1038/nature11017
  contributor:
    fullname: PJ Stephens
– volume: 38
  start-page: D787
  year: 2010
  ident: BFnmeth2689_CR10
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkp1014
  contributor:
    fullname: F Zhu
– volume: 466
  start-page: 869
  year: 2010
  ident: BFnmeth2689_CR15
  publication-title: Nature
  doi: 10.1038/nature09208
  contributor:
    fullname: Z Kan
– volume: 25
  start-page: 25
  year: 2000
  ident: BFnmeth2689_CR11
  publication-title: Nat. Genet.
  doi: 10.1038/75556
  contributor:
    fullname: M Ashburner
– ident: BFnmeth2689_CR14
  doi: 10.1038/nature11412
– volume: 8
  start-page: 587
  year: 2004
  ident: BFnmeth2689_CR29
  publication-title: Expert Opin. Ther. Targets
  doi: 10.1517/14728222.8.6.587
  contributor:
    fullname: AP Orth
– volume: 35
  start-page: D198
  year: 2007
  ident: BFnmeth2689_CR31
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkl999
  contributor:
    fullname: T Liu
– volume: 39
  start-page: D1060
  year: 2011
  ident: BFnmeth2689_CR25
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkq1037
  contributor:
    fullname: J von Eichborn
– volume: 10
  start-page: 1607
  year: 2005
  ident: BFnmeth2689_CR2
  publication-title: Drug Discov. Today
  doi: 10.1016/S1359-6446(05)03666-4
  contributor:
    fullname: AP Russ
– volume: 6
  start-page: S1758
  year: 2011
  ident: BFnmeth2689_CR8
  publication-title: J. Thorac. Oncol.
  doi: 10.1097/01.JTO.0000407557.30793.a6
  contributor:
    fullname: N Somaiah
– volume: 486
  start-page: 405
  year: 2012
  ident: BFnmeth2689_CR13
  publication-title: Nature
  doi: 10.1038/nature11154
  contributor:
    fullname: S Banerji
– volume: 9
  start-page: 104
  year: 2008
  ident: BFnmeth2689_CR27
  publication-title: BMC Bioinformatics
  doi: 10.1186/1471-2105-9-104
  contributor:
    fullname: Z Gao
– volume: 41
  start-page: D1104
  year: 2013
  ident: BFnmeth2689_CR26
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gks994
  contributor:
    fullname: AP Davis
– volume: 5
  start-page: 795
  year: 2011
  ident: BFnmeth2689_CR7
  publication-title: Biomarkers Med.
  doi: 10.2217/bmm.11.94
  contributor:
    fullname: EM McDonagh
– volume: 19
  start-page: 1894
  year: 2013
  ident: BFnmeth2689_CR19
  publication-title: Clin. Cancer Res.
  doi: 10.1158/1078-0432.CCR-12-1894
  contributor:
    fullname: P Yeh
– volume: 6
  start-page: 343
  year: 2010
  ident: BFnmeth2689_CR36
  publication-title: Mol. Syst. Biol.
  doi: 10.1038/msb.2009.98
  contributor:
    fullname: M Kuhn
– volume: 39
  start-page: D1035
  year: 2011
  ident: BFnmeth2689_CR6
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkq1126
  contributor:
    fullname: C Knox
– volume: 10
  start-page: 579
  year: 2011
  ident: BFnmeth2689_CR9
  publication-title: Nat. Rev. Drug Discov.
  doi: 10.1038/nrd3478
  contributor:
    fullname: M Rask-Andersen
– volume: 38
  start-page: D781
  year: 2010
  ident: BFnmeth2689_CR34
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkp934
  contributor:
    fullname: E Lim
– volume: 40
  start-page: D876
  year: 2012
  ident: BFnmeth2689_CR22
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr1011
  contributor:
    fullname: M Kuhn
– volume: 41
  start-page: D955
  year: 2013
  ident: BFnmeth2689_CR32
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gks1111
  contributor:
    fullname: W Yang
– volume: 39
  start-page: D800
  year: 2011
  ident: BFnmeth2689_CR3
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkq1064
  contributor:
    fullname: P Flicek
– volume: 40
  start-page: D400
  year: 2012
  ident: BFnmeth2689_CR5
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr1132
  contributor:
    fullname: Y Wang
– volume: 486
  start-page: 395
  year: 2012
  ident: BFnmeth2689_CR16
  publication-title: Nature
  doi: 10.1038/nature10933
  contributor:
    fullname: SP Shah
– volume: 313
  start-page: 1929
  year: 2006
  ident: BFnmeth2689_CR30
  publication-title: Science
  doi: 10.1126/science.1132939
  contributor:
    fullname: J Lamb
– volume: 8
  start-page: e67980
  year: 2013
  ident: BFnmeth2689_CR12
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0067980
  contributor:
    fullname: RD Kumar
– volume: 38
  start-page: D237
  year: 2010
  ident: BFnmeth2689_CR35
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkp970
  contributor:
    fullname: S Preissner
– volume: 486
  start-page: 361
  year: 2012
  ident: BFnmeth2689_CR37
  publication-title: Nature
  doi: 10.1038/nature11159
  contributor:
    fullname: E Lounkine
– volume: 40
  start-page: D306
  year: 2012
  ident: BFnmeth2689_CR20
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr948
  contributor:
    fullname: S Hunter
– volume: 3
  start-page: 224
  year: 2013
  ident: BFnmeth2689_CR18
  publication-title: Cancer Discov.
  doi: 10.1158/2159-8290.CD-12-0349
  contributor:
    fullname: R Bose
– volume: 40
  start-page: D290
  year: 2012
  ident: BFnmeth2689_CR21
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr1065
  contributor:
    fullname: M Punta
– volume: 298
  start-page: 1912
  year: 2002
  ident: BFnmeth2689_CR28
  publication-title: Science
  doi: 10.1126/science.1075762
  contributor:
    fullname: G Manning
– volume: 40
  start-page: D1113
  year: 2012
  ident: BFnmeth2689_CR23
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr912
  contributor:
    fullname: N Hecker
– volume: 483
  start-page: 603
  year: 2012
  ident: BFnmeth2689_CR33
  publication-title: Nature
  doi: 10.1038/nature11003
  contributor:
    fullname: J Barretina
– volume: 40
  start-page: D1100
  year: 2012
  ident: BFnmeth2689_CR24
  publication-title: Nucleic Acids Res.
  doi: 10.1093/nar/gkr777
  contributor:
    fullname: A Gaulton
SSID ssj0033425
Score 2.6299484
Snippet A database of known drug-gene interactions, with information derived from many public sources, allows the identification of genes that are currently targeted...
The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or...
SourceID pubmedcentral
proquest
gale
crossref
pubmed
springer
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 1209
SubjectTerms 631/114/129
631/114/2164
631/114/2401
631/154
Antineoplastic Agents - chemistry
Bioinformatics
Biological Microscopy
Biological Techniques
Biomedical Engineering/Biotechnology
Breast Neoplasms - drug therapy
Breast Neoplasms - genetics
brief-communication
Computational Biology - methods
Data Mining - methods
Databases, Genetic
Drug Discovery - methods
Drug Interactions
Drug therapy
Gene Expression Regulation - drug effects
Gene mutations
Genes
Genetic Variation
Genome
Genomes
Genomics
Genomics - methods
Humans
Information services
Life Sciences
Lung Neoplasms - drug therapy
Lung Neoplasms - genetics
Mines
Mutation
Online information services
Online services
Pharmaceutical research
Proteomics
Services
Software
Technology, Pharmaceutical - methods
Title DGIdb: mining the druggable genome
URI https://link.springer.com/article/10.1038/nmeth.2689
https://www.ncbi.nlm.nih.gov/pubmed/24122041
https://www.proquest.com/docview/1465000011
https://search.proquest.com/docview/1566849436
https://pubmed.ncbi.nlm.nih.gov/PMC3851581
Volume 10
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1ZT-MwEB5xaKV9QRzLEi6FQ-LJixs7ccIL4iqHtGiFQOpbZDtO4YGUo33g3zPjJqXtSrxESmwro5l45rM9mQ9gX-q0sDwrGcUihneaZYhbWUu6mJe4KIo9S8Tf2-TqQd504k694fZep1U2PtE76qJnaY_8EGd07LeiW8cvr4xYo-h0tabQmIX5qCXpmHb-9OL2313ji4WQnnaVcDlTKE5ToFSkhxVRNP-JEiJ4HwtJ0455LDJNZ01OHZ36iNRehIUaSoYnQ9svwYyrluHHkFzyYwV2zy-vC3MUPnsKiBCBXli8Dbpd-lcqpNKsz-4XPLQv7s-uWM2IwGwsoz5zzlkTWce1cKVKtI0KpbTNSq5TdBc0QVVSlCbROuEZoguLscdIrW2pFT4VqzBX9Sq3BmGcOZdZbVoIASU2psZwLZNSScOzgssA9hql5C_Dwhe5P7AWae5Vl5PqAjggfeU0G1ApVtdJ_fgOqiuVn4hY4IJIKhHA5kRP_IrtZHOj8byeRe_5l80D2Bk100jKDKtcb4B9EI-mMpMiCeD30EAjeRGdRBGXOFpNmG7UgWprT7ZUT4--xrZAJBqnOHK_MfKYWP-pYf176TfgZ0QsGj4LZhPm-m8Dt4VYpm-2YVZ1FF7T9uV2_fF-Am5_9FI
link.rule.ids 230,315,786,790,891,12083,12792,21416,27955,27956,31752,31753,33406,33407,33777,33778,43343,43633,43838,74100,74390,74657
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT9wwEB5RECqXildpCqXhIfVk8MZOnPRSoQJdnieQ9mbZjgM9kOWxe-DfM-NNlt2t1GMytjKasT2f7cl8APvS5KXjRcUoFjF8MqxA3Mo60qe8wk1RGlgirq6z7q0876W95sDtpUmrbNfEsFCXfUdn5Ic4o9NwFN359fjEiDWKblcbCo0PsCCFkDTOVW-84cI3gXSVUDlTqExbnlTkhzURNB8kGdG7TwSk2WV5Ii7N5kzOXJyGeHS6DJ8aIBkfjTy_AnO-XoXFEbXk6xrsHv85K-3P-CEQQMQI8-LyeXh3R39KxVSY9cGvw-3pyc3vLmv4EJhLZTJg3ntnE-e5Eb5SmXFJqZRxRcVNjosFTU-VlZXNjMl4gdjCYeSx0hhXGYVvxWeYr_u1_wJxWnhfOGM7CAAlCnNruZFZpaTlRcllBHutUfTjqOyFDtfVItfBdJpMF8EPspemuYBGcaZJ6cdvUFUpfSRSgdshqUQEW1MtcQy7aXFrcd3MoRf97vEIdsZi6kl5YbXvD7ENotFcFlJkEWyMHDTWF7FJknCJvdWU68YNqLL2tKT-ex8qbAvEoWmOPfdbJ0-o9Y8Zvv5f--_wsXtzdakvz64vNmEpIT6NkA-zBfOD56H_hqhmYLfD0H0DdKb0DA
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT9wwEB4VqiIuqNAHoRTSFqkns97YiZNeKlRYoKWohyJxs2zH2XIgC_s48O-Z8SbL7lbimIytWGPPzGd7Mh_AgTR56XhRMYpFDJ8MKxC3sq70Ka9wU5QGlojfl9nZlfx5nV43-U-jJq2y9YnBUZcDR2fkHbToNBxFdztVkxbx57j3_e6eEYMU3bQ2dBor8JJANtE45L3T1isLIQMBKyF0pnBgbalSkXdqIms-TDKiep8LTssuei5GLedPLl2ihtjUew0bDaiMj6arYBNe-HoLXk1pJh_ewOfj0_PSfotvAxlEjJAvLoeTfp_-moqpSOutfwtXvZO_P85Yw43AXCqTMfPeO5s4z43wlcqMS0qljCsqbnJ0HGSqKisrmxmT8QJxhsMoZKUxrjIK34p3sFoPar8NcVp4XzhjuwgGJQpza7mRWaWk5UXJZQRfWqXou2kJDB2urkWug-o0qS6Cr6QvTXaBSnGmSe_Hb1CFKX0kUoFbI6lEBLsLLXE9u0Vxq3Hd2NNIP81-BJ9mYupJOWK1H0ywDSLTXBZSZBG8n07QbLyIU5KES-ytFqZu1oCqbC9K6pt_odq2QEya5tjzoJ3kuWH9p4ad50e_D2u4avXF-eWvD7CeELVGSI3ZhdXxcOI_IsAZ272wch8B5sP4QQ
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=DGIdb+-+Mining+the+druggable+genome&rft.jtitle=Nature+methods&rft.au=Griffith%2C+Malachi&rft.au=Griffith%2C+Obi+L.&rft.au=Coffman%2C+Adam+C.&rft.au=Weible%2C+James+V.&rft.date=2013-12-01&rft.issn=1548-7091&rft.eissn=1548-7105&rft.volume=10&rft.issue=12&rft.spage=1209&rft.epage=1210&rft_id=info:doi/10.1038%2Fnmeth.2689&rft_id=info%3Apmid%2F24122041&rft.externalDBID=PMC3851581
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1548-7091&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1548-7091&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1548-7091&client=summon