Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

A cellular-level study of the pathophysiology is crucial for understanding the mechanisms behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques show promises for the cellular-level understanding of the pathophysiology of diseases. To provide important insight on how t...

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Published inSensors Vol. 13; no. 4; pp. 4170 - 4191
Main Authors Lee, KyeoReh, Kim, Kyoohyun, Jung, Jaehwang, Heo, JiHan, Cho, Sangyeon, Lee, Sangyun, Chang, Gyuyoung, Jo, YoungJu, Park, Hyunjoo, Park, YongKeun
Format Journal Article Book Review
LanguageEnglish
Published Switzerland MDPI AG 28.03.2013
Molecular Diversity Preservation International (MDPI)
Subjects
Anemia, Sickle Cell - pathology
bio-photonics
Biomechanical Phenomena
Cell Death
Cell Division
cell physiology
Cell Proliferation
Cells - pathology
Erythrocytes - pathology
Homeostasis
Humans
Imaging, Three-Dimensional - methods
microscopy
Neoplasms - pathology
optical imaging
quantitative phase imaging
Review
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Summary:A cellular-level study of the pathophysiology is crucial for understanding the mechanisms behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques show promises for the cellular-level understanding of the pathophysiology of diseases. To provide important insight on how the QPI techniques potentially improve the study of cell pathophysiology, here we present the principles of QPI and highlight some of the recent applications of QPI ranging from cell homeostasis to infectious diseases and cancer.
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ISSN:1424-8220
1424-8220
DOI:10.3390/s130404170