When the brain takes ‘BOLD’ steps: Real-time fMRI neurofeedback can further enhance the ability to gradually self-regulate regional brain activation

• Published in: Neuroscience Vol. 378; pp. 71 - 88
• Main Authors: Sorger, Bettina, Kamp, Tabea, Weiskopf, Nikolaus, Peters, Judith Caroline, Goebel, Rainer
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 15.05.2018; Elsevier Science
• Subjects: (gradual) self-regulation; (real-time) functional magnetic resonance imaging; Adult; Brain - diagnostic imaging; Brain - physiology; Brain Mapping; brain-computer interface; Cerebrovascular Circulation; cognitive strategies; Feasibility Studies; Female; Humans; Magnetic Resonance Imaging; Male; Mental Processes - physiology; mental tasks; neurofeedback; Neurofeedback - methods; Neurofeedback - physiology; Neurofeedback - radiation effects; Neurology; Oxygen - blood; Time Factors; Young Adult; (real-time) functional magnetic resonance imaging; brain-computer interface; (gradual) self-regulation; blood oxygenation level-dependent; (f)MRI; (f)NIRS; ‘locked-in’ syndrome; (functional) near-infrared spectroscopy; real-time functional magnetic resonance imaging; cognitive strategies; VOI(s); (functional) magnetic resonance imaging; LIS; echo-planar imaging; volume(s) of interest; BOLD; ROI(s); rtfMRI; mental tasks; region(s) of interest; EPI; neurofeedback
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2016.09.026

Highlights • Humans are able to gradually self-regulate regional brain activation by applying cognitive strategies. • Providing rtfMRI neurofeedback can enhance the gradual self-regulation ability. • Findings are generalizable to various mental tasks and clinical MR field strengths. • Novel parametric activation paradigm enriches spectrum of rtfMRI-neurofeedback and BCI methodology.