Cigarette Smoking Associated with Attention Deficit Hyperactivity Disorder

• Published in: The Journal of pediatrics Vol. 153; no. 3; pp. 414 - 419.e1
• Main Authors: Wilens, Timothy E., MD, Vitulano, Michael, BA, Upadhyaya, Himanshu, MD, Adamson, Joel, BA, Sawtelle, Robert, BA, Utzinger, Linsey, BA, Biederman, Joseph, MD
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.09.2008; Elsevier
• Subjects: Adolescent; Adult; Attention - physiology; Attention Deficit Disorder with Hyperactivity - epidemiology; Attention Deficit Disorder with Hyperactivity - etiology; Attention Deficit Disorder with Hyperactivity - psychology; Biological and medical sciences; Female; Follow-Up Studies; General aspects; Humans; Male; Medical sciences; Pediatrics; Prevalence; Prognosis; Psychometrics - methods; Retrospective Studies; Sex Distribution; Smoking - adverse effects; Socioeconomic Factors; Surveys and Questionnaires; Time Factors; Tobacco, tobacco smoking; Toxicology; United States - epidemiology; United States; SES; ADHD; CD; Diagnostic and Statistical Manual of Mental Disorders; FTQ; Socioeconomic status; mFTQ; Fagerström Tolerance Questionnaire; Attention deficit hyperactivity disorder; Conduct disorder; SCID; K-SADS-E; Structured Clinical Interview for DSM-IV; Schedule for Affective Disorders and Schizophrenia for School-Aged Children, Epidemiologic Version; Modified Fagerström Tolerance Questionnaire; DSM; Pediatrics; Concomitant disease; Attention disorder with hyperactivity; Tobacco smoking
• ISSN: 0022-3476; 1097-6833
• DOI: 10.1016/j.jpeds.2008.04.030

Objective To evaluate the association between attention deficit hyperactivity disorder (ADHD) and severity of physical dependence on nicotine in a controlled study of adolescents and young adults with ADHD. Study design In controlled longitudinal family studies of ADHD, we examined self-reports on the modified Fagerström Tolerance Questionnaire (mFTQ) for degrees of physical dependence on nicotine. Results We obtained mFTQ data from 80 ADHD probands and 86 control probands (mean age, 19.2 years). The smokers with ADHD had significantly higher scores on the mFTQ, indicative of more severe physical dependence on nicotine. Similarly, in current smokers, a positive linear relationship was found between mFTQ score and both inattentive and hyperactive ADHD symptoms. Environmental factors, such as current parental smoking, peer smoking, and living with a smoker, all increased the risk for smoking in those with ADHD compared with controls. Conclusion Male and female smokers with ADHD manifest more severe physical dependence on smoking compared with controls. Important environmental factors appear to add to the risk of smoking associated with ADHD.