Evaluation of pooled ocular and vaginal swabs by the Cepheid GeneXpert CT/NG assay for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae compared to the GenProbe Aptima Combo 2 Assay

Abstract Ocular swabs from Tanzania were tested for Chlamydia trachomatis (CT), and self-collected vaginal swabs collected through a home collection program, iwantthekit.org, were tested for Neisseria gonorrhoeae and CT to evaluate Cepheid GeneXpert for the use of pooling multiple specimens before t...

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Published inDiagnostic microbiology and infectious disease Vol. 81; no. 2; pp. 102 - 104
Main Authors Dize, L, West, S.K, Mkocha, H, Quinn, T.C, Gaydos, C.A
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.02.2015
Subjects
Chlamydia Infections - diagnosis
Chlamydia trachomatis
Chlamydia trachomatis - genetics
Chlamydia trachomatis - isolation & purification
Eye - microbiology
Female
Gonorrhea - diagnosis
Humans
Infectious Disease
Internal Medicine
Male
Molecular Diagnostic Techniques - methods
Neisseria gonorrhoeae
Neisseria gonorrhoeae - genetics
Neisseria gonorrhoeae - isolation & purification
Pooling
Specimen Handling - methods
Tanzania
Trachoma
Vagina - microbiology
Tanzania
Trachoma
Chlamydia trachomatis
Neisseria gonorrhoeae
Pooling
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Summary:Abstract Ocular swabs from Tanzania were tested for Chlamydia trachomatis (CT), and self-collected vaginal swabs collected through a home collection program, iwantthekit.org, were tested for Neisseria gonorrhoeae and CT to evaluate Cepheid GeneXpert for the use of pooling multiple specimens before testing. GeneXpert shows to be a promising test for pooling.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2014.11.010