Serum aflatoxin levels of the healthy adult population living in the north and south regions of Turkey

• Published in: Public health nutrition Vol. 17; no. 11; pp. 2496 - 2504
• Main Authors: Aydin, Sevtap, Sabuncuoglu, Suna, Erkekoglu, Pinar, Şahin, Gönül, Giray, Belma Kocer
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.11.2014
• Subjects: Adolescent; Adult; Aflatoxin B1 - blood; Aflatoxins; Aflatoxins - blood; Agricultural commodities; Animals; Carcinogens; Cereals; Chromatography, High Pressure Liquid; Enzymes; European Continental Ancestry Group; Female; Food; Food Contamination - analysis; Food Microbiology; Food Safety; Harvest; Healthy Volunteers; Hepatitis B; Humans; Liquid chromatography; Liver cancer; Male; Mediterranean Region; Middle Aged; Monitoring and Surveillance; Mycotoxins; Population; Rural areas; Rural Population; Seasons; Summer; Toxicity; Turkey; Winter; Young Adult; United States > US; Black Sea; Turkey; Aflatoxins; Turkey; HPLC; Healthy adult population; Mycotoxin
• ISSN: 1368-9800; 1475-2727
• DOI: 10.1017/S1368980013002802

To determine the serum concentrations of aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1) and aflatoxin G2 (AFG2) in the healthy adult population living in both the Black Sea and Mediterranean regions of Turkey and to investigate the regional, seasonal and gender variability in aflatoxins (AF) exposure in these regions. Serum AFB1, AFB2, AFG1 and AFG2 concentrations were analysed by HPLC. Settings In total, four hundred and eighty-four serum samples were analysed. Four hundred and eighty-four healthy adult volunteers living in rural areas of the Black Sea and Mediterranean regions of Turkey were studied. The mean serum concentration of total AF in the Black Sea region was 1·33 ppb (min-max 0·15-3·38 ppb) and 0·90 ppb (min-max 0·18-2·48 ppb) for summer and winter, respectively. In the Mediterranean region, the mean serum concentration of total AF was determined as 0·55 ppb (range 0·04-1·72 ppb) for summer and 0·45 ppb (range 0·12-1·43 ppb) for winter. The total AF concentrations in serum samples were statistically higher in summer compared with winter for the two regions. The differences between the regions were statistically significant concerning all samples, with higher total AF concentrations in the Black Sea region. The overall results suggest that the Turkish population living in these two regions is continuously exposed to AF, particularly in the summer, and that mycotoxin contamination in food should be monitored routinely for food safety and human health.