Validity of the Hospital Anxiety and Depression Scale and the Beck Depression Inventory for use in end-stage renal disease patients

• Published in: British journal of clinical psychology Vol. 49; no. 4; pp. 507 - 516
• Main Authors: Loosman, W. L., Siegert, C. E. H., Korzec, A., Honig, A.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.11.2010; British Psychological Society
• Subjects: Aged; Anxiety; Anxiety-Depression; Biological and medical sciences; Clinical assessment; Comparative analysis; Cross-Sectional Studies; Depression; Depressive Disorder, Major - diagnosis; Depressive Disorder, Major - epidemiology; Depressive Disorder, Major - psychology; Diagnosis; Diagnostic and Statistical Manual of Mental Disorders; Diseases; Female; Hospitals; Humans; Kidney diseases; Kidney Failure, Chronic - psychology; Kidney Failure, Chronic - therapy; Male; Mass Screening - statistics & numerical data; Measurement; Medical sciences; Middle Aged; Netherlands; Patients; Peritoneal Dialysis - psychology; Personality Inventory - statistics & numerical data; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychometrics - statistics & numerical data; Psychometrics. Diagnostic aid systems; Psychopathology. Psychiatry; Renal Dialysis - psychology; Reproducibility of Results; ROC Curve; Screening; Sick Role; Statistical analysis; Techniques and methods; Validity; Netherlands; Kidney disease; Mood disorder; Human; Hospital Anxiety and Depression Scale Zigmond Snaith; Urinary system disease; Questionnaire; Chronic renal failure; Psychometrics; Depression; Test validation; Cutoff note; Depression Inventory Beck; Receiver operating characteristic curves; Predictive validity; Comparative study
• ISSN: 0144-6657; 2044-8260
• DOI: 10.1348/014466509X477827

Objective. To validate the Hospital Anxiety and Depression Scale (HADS) and the Beck Depression Inventory (BDI) for use in patients with end‐stage renal disease (ESRD) and to compare the outcome of both screening measures with each other. Design. Cross‐sectional and between‐subjects design. The independent variable was the diagnosis depression by the Mini International Neuropsychiatric Interview (MINI). The dependent variables were the HADS and BDI total score. Methods. All 130 patients with ESRD who were treated with haemodialysis (HD) or peritoneal dialyses in the Sint Lucas Andreas Hospital in Amsterdam were eligible for this study and were asked to fill out both HADS and BDI. The outcomes of both rating scales were compared with the diagnosis major depressive episode based on the MINI, which was seen as the gold standard. Receiver operating characteristic curves were used to choose optimal cut‐off values. Results. Of 62 enrolled subjects, 21 (34%) were diagnosed with a depressive disorder. Optimal cut‐off values were ≥12 (HADS) and ≥13 (BDI). Sensitivity was 81.0% (HADS) and 75.0% (BDI). Specificity was 90.2% for both. Conclusions. Both HADS and BDI are valid screening instruments for the diagnosis depression in ESRD patients but there is no statistical difference found between both rating scales.