Orthogonal Assembly of Nanoparticle Building Blocks on Dip-Pen Nanolithographically Generated Templates of DNA

Nanoscale construction work with DNA: Dip‐pen nanolithography (DPN) is used to generate nanostructures which can be subsequently functionalized with oligonucleotides a′ and b′ and used to assemble, in an orthogonal manner, gold nanoparticles (a, b in scheme) functionalized with sequences complementa...

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Published inAngewandte Chemie (International ed.) Vol. 40; no. 16; pp. 3071 - 3073
Main Authors Demers, Linette M., Park, So-Jung, Taton, T. Andrew, Li, Zhi, Mirkin, Chad A.
Format Journal Article
LanguageEnglish
Published Weinheim WILEY-VCH Verlag 17.08.2001
WILEY‐VCH Verlag
Subjects
Assembly
Construction
Deoxyribonucleic acid
DNA recognition
Gene sequencing
Gold
monolayers
nanolithography
Nanoparticles
Nanostructure
nanostructures
Oligonucleotides
self-assembly
gold
self-assembly
DNA recognition
nanolithography
monolayers
nanostructures
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Summary:Nanoscale construction work with DNA: Dip‐pen nanolithography (DPN) is used to generate nanostructures which can be subsequently functionalized with oligonucleotides a′ and b′ and used to assemble, in an orthogonal manner, gold nanoparticles (a, b in scheme) functionalized with sequences complementary to the DPN‐generated structures.
Bibliography:CAM acknowledges the AFOSR, DARPA, and NSF for support of this research. LMD thanks NSERC (Canada) for a graduate fellowship.
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ArticleID:ANIE3071
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content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/1521-3773(20010817)40:16<3071::AID-ANIE3071>3.0.CO;2-S