Hypothermia is an independent risk factor for prolonged ICU stay in coronary artery bypass surgery: an observational study

• Published in: Scientific reports Vol. 13; no. 1; pp. 4626 - 7
• Main Authors: Wang, Yi-Chia, Huang, Hsing-Hao, Lin, Pei-Ching, Wang, Ming-Jiuh, Huang, Chi-Hsiang
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.03.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/308/409; 692/499; Bypass; Coronary artery; Coronary Artery Bypass - adverse effects; Ejection fraction; Heart; Heart surgery; Humanities and Social Sciences; Humans; Hypothermia; Intensive Care Units; Ischemia; Length of Stay; Morbidity; Mortality; multidisciplinary; Myocardial ischemia; Observational studies; Oxygen demand; Retrospective Studies; Risk Factors; Science; Science (multidisciplinary); Stroke Volume; Surgical site infections; Surgical Wound Infection - etiology; Ventricle; Ventricular Function, Left
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-31889-x

Maintenance of normothermia is a critical perioperative issue. The warming process after hypothermia tends to increase oxygen demand, which may lead to myocardial ischemia. This study explored whether hypothermia was an independent risk factor for increased morbidity and mortality in patients receiving CABG. We conducted a retrospective observational study of CABG surgeries performed from January 2018 to June 2019. The outcomes of interest were mortality, surgical site infection rate, ventilator dependent time, intensive care unit (ICU) stay, and hospitalization duration. Data from 206 patients were analysed. Hypothermic patients were taller (p = 0.012), had lower left ventricular ejection fraction (p = 0.016), and had off-pump CABG more frequently (p = 0.04). Our analysis noted no incidence of mortality within 30 days. Hypothermia was not associated with higher surgical site infection rate or longer intubation time. After adjusting for sex, age, cardiopulmonary bypass duration, left ventricular ejection fraction, and EuroSCORE II, higher EuroSCORE II (p < 0.001; odds ratio 1.2) and hypothermia upon ICU admission (p = 0.04; odds ratio 3.8) were independent risk factors for prolonged ICU stay. In addition to EuroSCORE II, hypothermia upon ICU admission was an independent risk factor for prolonged ICU stay in patients receiving elective CABG.