Unique patterns of medial meniscus extrusion during walking and its association with limb kinematics in patients with knee osteoarthritis

• Published in: Scientific reports Vol. 13; no. 1; p. 12513
• Main Authors: Ishii, Yosuke, Ishikawa, Masakazu, Nakashima, Yuko, Hashizume, Takato, Okamoto, Saeko, Kamei, Goki, Okada, Kaoru, Takagi, Kazuya, Takahashi, Makoto, Adachi, Nobuo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.08.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4023/1670; 692/4023/1671; Aged; Arthritis; Biomechanical Phenomena; Biomechanics; Gait; Humanities and Social Sciences; Humans; Kinematics; Knee; Knee Joint - diagnostic imaging; Mechanical properties; Menisci, Tibial - diagnostic imaging; Meniscus; multidisciplinary; Older people; Osteoarthritis; Osteoarthritis, Knee - diagnostic imaging; Science; Science (multidisciplinary); Walking
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-39715-0

Medial meniscus extrusion (MME) is exacerbated by repeated mechanical stress. Various factors would affect MME; however, there is limited information about the behaviour of the medial meniscus during walking in patients with knee osteoarthritis (KOA). This study aimed to investigate the pattern of MME during walking and its association with limb biomechanics in patients with KOA. Fifty-five patients with KOA and ten older adult volunteers as a control group were involved in this study. The MME and limb biomechanics during walking were evaluated simultaneously by ultrasound and a motion analysis system, respectively. The waveform was constructed from the values of MME, and the point showing the highest value of MME was identified during the gait cycle. According to the peak timing of MME in the waveform, the pattern of the waveform was evaluated and compared to the control group. Lateral thrust, knee adduction moment (KAM), and flexion moment were obtained from motion analysis, and their association with the MME was evaluated. The patients with KOA demonstrated unique peak timing during walking. Compared to the control group, there were three groups of MME waveforms, early (< 59%), normal (60–83%), and late (> 84%) from the peak timing in the gait cycle. The pattern of MME waveform in early, normal, and late groups was correlated with the first KAM and lateral thrust, second KAM, and knee flexion moment, respectively. A unique MME pattern during walking was demonstrated, and these patterns were associated with limb biomechanics in patients with KOA.