Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab

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Bibliographic Details
Published inCell research Vol. 27; no. 1; pp. 147 - 150
Main Authors Na, Zhenkun, Yeo, Siok Ping, Bharath, Sakshibeedu R, Bowler, Matthew W, Balıkçı, Esra, Wang, Cheng-I, Song, Haiwei
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.01.2017
Nature Publishing Group
Subjects
631/45/535
631/67/1059/602
692/700/565/251/1574
Amino Acid Sequence
Animals
Antibodies, Blocking - chemistry
Antibodies, Blocking - therapeutic use
Antibodies, Monoclonal, Humanized - chemistry
Antibodies, Monoclonal, Humanized - therapeutic use
Biomedical and Life Sciences
Cell Biology
Humans
Immunity
Letter to the Editor
Life Sciences
Ligands
Mice
Programmed Cell Death 1 Receptor - chemistry
Programmed Cell Death 1 Receptor - metabolism
Structure-Activity Relationship
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ISSN:1001-0602
1748-7838
1748-7838
DOI:10.1038/cr.2016.77