New-Onset Diabetes in COVID-19: Time to Frame Its Fearful Symmetry

There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as...

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Published inDiabetes therapy Vol. 12; no. 2; pp. 461 - 464
Main Authors Papachristou, Stella, Stamatiou, Iliana, Stoian, Anca P., Papanas, Nikolaos
Format Journal Article
LanguageEnglish
Published Cheshire Springer Healthcare 01.02.2021
Springer
Springer Nature B.V
Subjects
Cardiology
Care and treatment
Commentary
Coronaviruses
COVID-19
Development and progression
Diabetes
Diagnosis
Drug therapy
Endocrinology
Hyperglycemia
Insulin
Insulin resistance
Internal Medicine
Medicine
Medicine & Public Health
Greece
Corona virus infectious disease
Diabetes mellitus
Ketoacidosis
New-onset diabetes
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Summary:There is increasing evidence that coronavirus disease 2019 (COVID-19) may lead to new-onset diabetes mellitus (DM). This may occur even in patients without predisposing factors for impaired glucose metabolism. Both impaired pancreatic insulin secretion and insulin resistance have been implicated as underlying mechanisms. Importantly, new-onset hyperglycaemia is associated with worse prognosis in patients with COVID-19. Indeed, its prognosis may be even more sinister than in patients with pre-existing DM. More research data and knowledge are currently being collected to improve our insights into this constellation and to guide therapies in clinical reality.
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ISSN:1869-6953
1869-6961
DOI:10.1007/s13300-020-00988-7