Genetic polymorphism of the thrombospondin-related apical merozoite protein (TRAMP) of Plasmodium knowlesi in Malaysia

• Published in: Parasitology research (1987) Vol. 122; no. 1; pp. 195 - 200
• Main Authors: Ng, Yee Ling, Lau, Yee Ling, Hamid, Mohd Hafizi Abdul, Jelip, Jenarun, Ooi, Choo Huck, Mudin, Rose Nani, Jaimin, Joel Judson, Fong, Mun Yik
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.01.2023; Springer; Springer Nature B.V
• Subjects: Amino acid sequence; Amino acids; Analysis; Animals; Biomedical and Life Sciences; Biomedicine; Clinical isolates; Cloning vectors; Gene polymorphism; Genetic aspects; Genetic polymorphisms; Genetic Variation; Genetic vectors; Haplotypes; Health aspects; Humans; Immunology; Malaria; Malaria - parasitology; Malaysia; Medical Microbiology; Merozoites - metabolism; Microbiology; Natural selection; Nucleotide sequence; Plasmodium falciparum; Plasmodium knowlesi; Plasmodium knowlesi - genetics; Plasmodium knowlesi - metabolism; Polymorphism; Polymorphism, Genetic; Protozoan Proteins - genetics; Protozoan Proteins - metabolism; Thrombospondin; Malaysia; Indonesia; Borneo; Haplotypes; Thrombospondin-related apical merozoite protein; Genetic polymorphism; Plasmodium knowlesi

  Plasmodium knowlesi is a simian malaria parasite that causes significant zoonotic infections in Southeast Asia, particularly in Malaysia. The Plasmodium thrombospondin-related apical merozoite protein (TRAMP) plays an essential role in the invasion of the parasite into its host erythrocyte. The pr...