Incorporating catechol into electroactive polypyrrole nanowires on titanium to promote hydroxyapatite formation

To improve the osteointegration property of biomedical titanium, nano-architectured electroactive coating was synthesized through the electrochemical polymerization of dopamine and pyrrole. The highly binding affinity of Ca2+ to the catechol moiety of doped dopamine enabled efficient interaction bet...

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Published inBioactive materials Vol. 3; no. 1; pp. 74 - 79
Main Authors Wang, Zhengao, Zeng, Jinquan, Tan, Guoxin, Liao, Jingwen, Zhou, Lei, Chen, Junqi, Yu, Peng, Wang, Qiyou, Ning, Chengyun
Format Journal Article
LanguageEnglish
Published China Elsevier B.V 01.03.2018
KeAi Publishing
KeAi Communications Co., Ltd
Subjects
Catechol
Hydroxyapatite
Nanowires
Polypyrrole
Titanium
Titanium
Hydroxyapatite
Catechol
Nanowires
Polypyrrole
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Summary:To improve the osteointegration property of biomedical titanium, nano-architectured electroactive coating was synthesized through the electrochemical polymerization of dopamine and pyrrole. The highly binding affinity of Ca2+ to the catechol moiety of doped dopamine enabled efficient interaction between polypyrrole/polydopamine nanowires and mineral ions. The results indicate that the PPy/PDA nanowires preserved its efficient electro-activity and accelerated the hydroxyapatite deposition in a simulated body fluid. The PPy/PDA nanowires coating could be applied to promote the osteointegration of titanium implant. [Display omitted] •Nanowires were constructed through electrochemical polymerization of pyrrole and dapamine•The PPy/PDA nanowires possessed wonderful electroactivity.•The PPy/PDA nanowires could promote Hydroxyapatite formation.
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ISSN:2452-199X
2452-199X
DOI:10.1016/j.bioactmat.2017.05.006