Genetic and Antigenic Characteristics of Highly Pathogenic Avian Influenza A(H5N8) Viruses Circulating in Domestic Poultry in Egypt, 2017–2021

• Published in: Microorganisms (Basel) Vol. 10; no. 3; p. 595
• Main Authors: Kandeil, Ahmed, Moatasim, Yassmin, El Taweel, Ahmed, El Sayes, Mohamed, Rubrum, Adam, Jeevan, Trushar, McKenzie, Pamela P., Webby, Richard J., Ali, Mohamed A., Kayali, Ghazi, El-Shesheny, Rabeh
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 09.03.2022; MDPI
• Subjects: Amino acids; Antigenic characteristics; Antigenic drift; antigenic variation; Antigens; antiviral agents; Avian flu; avian influenza; Bird migration; Drug resistance; Egypt; genes; Genomes; Genotypes; H5N8; Hemagglutinins; Heterogeneity; highly pathogenic avian influenza; indigenous species; Influenza; Influenza A; monitoring; Mutation; Pathogenicity; Pathogens; phylogenetic analysis; Phylogenetics; Poultry; Poultry production; Public health; reassortment; Viral infections; Virulence; Viruses; England; United Kingdom > UK; United States > US; China; Germany; Egypt; highly pathogenic avian influenza; reassortment; phylogenetic analysis; H5N8; Egypt

In Egypt, the endemicity of avian influenza viruses is a serious concern. Since 2016, several outbreaks of H5N8 have been recorded among domestic poultry in various areas of the country. Active surveillance of domestic poultry across several governorates in Egypt from 2017 to 2021 detected at least...