Impact of delivery time factor on treatment time and plan quality in tomotherapy

• Published in: Scientific reports Vol. 13; no. 1; p. 12207
• Main Authors: Yagihashi, Takayuki, Inoue, Tatsuya, Shiba, Shintaro, Yamano, Akihiro, Minagawa, Yumiko, Omura, Motoko, Inoue, Kazumasa, Nagata, Hironori
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.07.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/67/1059/485; 631/67/1536; 631/67/1612; 631/67/589/466; Cancer therapies; Conformity; Efficiency; Head & neck cancer; Humanities and Social Sciences; Lung cancer; multidisciplinary; Patients; Planning; Prostate cancer; Radiation therapy; Science; Science (multidisciplinary); Spinal cord
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-023-39047-z

Delivery time factor (DTF) is a new parameter introduced by the RayStation treatment planning system for tomotherapy treatment planning. This study investigated the effects of this factor on various tomotherapy plans. Twenty-five patients with cancer (head and neck, 6; lung, 9; prostate, 10) were enrolled in this study. Helical tomotherapy plans with a field width of 2.5 cm, pitch of 0.287, and DTF of 2.0 were created. All the initial plans were recalculated by changing the DTF parameter from 1.0 to 3.0 in increments of 0.1. Then, DTF’s impact on delivery efficiency and plan quality was evaluated. Treatment time and modulation factor increased monotonically with increasing DTF. Increasing the DTF by 0.1 increased the treatment time and modulation factor by almost 10%. This relationship was similar for all treatment sites. Conformity index (CI), homogeneity index, and organ at risk doses were improved compared to plans with a DTF of 1.0, except for the CI in the lung cancer case. However, the improvement in most indices ceased at a certain DTF; nevertheless, treatment time continued to increase following an increase in DTF. DTF is a critical parameter for improving the quality of tomotherapy plans.