Long COVID prevalence and impact on quality of life 2 years after acute COVID-19

There has been an increasing interest in the long-term impact of long COVID. However, only a few studies have investigated the clinical manifestations of long COVID 24 months after acute COVID infection. In this study, prospective online surveys were conducted in adults previously diagnosed with cor...

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Published inScientific reports Vol. 13; no. 1; p. 11207
Main Authors Kim, Yoonjung, Bae, Sohyun, Chang, Hyun-Ha, Kim, Shin-Woo
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 11.07.2023
Nature Publishing Group
Nature Portfolio
Subjects
631/326/596
692/699/255
Adult
Amnesia
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 Vaccines
Humanities and Social Sciences
Humans
Immunization
multidisciplinary
Post-Acute COVID-19 Syndrome
Prevalence
Prospective Studies
Quality of Life
Science
Science (multidisciplinary)
Sleep disorders
Surveys
Vaccination
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Summary:There has been an increasing interest in the long-term impact of long COVID. However, only a few studies have investigated the clinical manifestations of long COVID 24 months after acute COVID infection. In this study, prospective online surveys were conducted in adults previously diagnosed with coronavirus disease 2019 (COVID-19) in South Korea between February 13 and March 13, 2020, at 6, 12, and 24 months after COVID-19. We investigated self-reported symptoms and the EuroQol-5-dimension index. Among 900 individuals enrolled initially, 150 completed all 3 surveys. After excluding the cases of COVID-19 reinfection, 132 individuals were included in the final analysis. Among the 132 participants, 94 (71.2%) experienced symptoms of long COVID. The most frequently reported symptoms were fatigue (34.8%), amnesia (30.3%), concentration difficulties (24.2%), insomnia (20.5%), and depression (19.7%). Notably, no significant differences were noted in the incidence of long COVID at 24 months in terms of the number of vaccinations received. Although the neuropsychiatric quality of life improved over time, it continued to affect 32.7% of participants. Symptoms of long COVID, particularly neuropsychiatric symptoms, tend to persist over time, and COVID-19 vaccination or the number of vaccinations received may not significantly affect the incidence of long COVID.
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ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-36995-4