RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner

• Published in: Leukemia Vol. 35; no. 10; pp. 2983 - 2988
• Main Authors: Abdallah, Mohamed Gaber, Niibori-Nambu, Akiko, Morii, Mariko, Yokomizo, Takako, Yokomizo, Tomomasa, Ideue, Takako, Kubota, Sho, Teoh, Vania Swee Imm, Mok, Michelle Meng Huang, Wang, Chelsia Qiuxia, Omar, Abdellah Ali, Tokunaga, Kenji, Iwanaga, Eisaku, Matsuoka, Masao, Asou, Norio, Nakagata, Naomi, Araki, Kimi, AboElenin, Mabrouk, Madboly, Sayed Hamada, Sashida, Goro, Osato, Motomi
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.10.2021; Nature Publishing Group
• Subjects: 13/100; 13/31; 14/35; 14/63; 45/77; 631/208/68; 631/67/1990/283/1897; 64/110; Age; Age Factors; Age factors in disease; Animals; Blood; Cancer Research; Core Binding Factor Alpha 2 Subunit - physiology; Critical Care Medicine; Development and progression; DNA-Binding Proteins - genetics; Flow cytometry; Genetic aspects; Health aspects; Hematology; Intensive; Internal Medicine; Letter; Leukemia; Leukemia, Myeloid - genetics; Leukemia, Myeloid - metabolism; Leukemia, Myeloid - pathology; Medicine; Medicine & Public Health; Mice; Mice, Knockout; Morphology; Myelocytic leukemia; Myeloid leukemia; Nonlymphoid leukemia; Oncogene Proteins, Fusion; Oncology; Proto-Oncogene Proteins - genetics; Runx1 protein; RUNX1 Translocation Partner 1 Protein - physiology; Transcription factors; Transcription Factors - genetics; Translocation, Genetic; Japan
• ISSN: 0887-6924; 1476-5551
• DOI: 10.1038/s41375-021-01268-4