The current performance of biodegradable magnesium-based implants in magnetic resonance imaging: A review

• Published in: Bioactive materials Vol. 6; no. 12; pp. 4360 - 4367
• Main Authors: Espiritu, Jonathan, Meier, Martin, Seitz, Jan-Marten
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.12.2021; KeAi Publishing; KeAi Communications Co., Ltd
• Subjects: Biodegradable implants; Magnesium; Magnetic resonance imaging; Medical imaging; Patient safety; Patient safety; Medical imaging; Magnesium; Magnetic resonance imaging; Biodegradable implants
• ISSN: 2452-199X; 2452-199X
• DOI: 10.1016/j.bioactmat.2021.04.012

Magnesium-based implants are re-emerging as a substantial amendment to standard orthopaedic implants. A brief introduction of magnesium (Mg) as a biodegradable material and basic magnetic resonance imaging (MRI) principles are discussed. This review aims to highlight the current performance of these implants during examinations with MRI. We also aim to summarise comparisons between Mg-based implants with current standards to emphasise the promotion of biodegradable implants in clinical practice. A comprehensive search of current literature on Mg-based implants and the utilisation of MRI in the studies was performed. Additionally, recorded artefact behaviour of Mg-based implants during MRI was investigated. A total of nine studies were included in which MRI was employed to image Mg-based implants. Of those studies, four of the nine discuss artefact production caused by the implants. MRI successfully imaged regions of interest over all and produced fewer artefacts than other materials used in the studies. MRI was employed in contrast angiography, bone growth observation, bone infection healing, and blood perfusion. Imaging capabilities of an implant material are vital to translating products into clinical application. Positive findings presented in this review suggest and support the use of Mg-based implants due to their successful visual compatibility with MRI techniques. •Mg materials have shown to safely degrade in-vivo as a load-bearing implant.•Magnesium-based implants have successfully been visualised with MRI.•Magnesium produces lower metallic artefact than titanium and stainless steel.