Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells
Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shin...
Saved in:
| Published in | Food science and biotechnology Vol. 31; no. 5; pp. 617 - 625 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Singapore
Springer Nature Singapore
01.05.2022
Springer Nature B.V 한국식품과학회 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1226-7708 2092-6456 2092-6456 |
| DOI | 10.1007/s10068-022-01055-6 |
Cover
Loading…
| Abstract | Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from
Porphyra
spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (
Porphyra dentata
) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. |
|---|---|
| AbstractList | Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. KCI Citation Count: 3 Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver ( Porphyra dentata ) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver ( ) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes.Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes. Shinorine and porphyra-334 were extracted from laver (Porphyra dentata) 50% methanolic (MeOH) extract of and their structures were elucidated by MS and NMR spectroscopy. Both compounds had no cytotoxic effect in 3T3-L1 cells (< 200 μg/mL) and inhibited the accumulation of lipid droplets in 3T3-L1 mature adipocytes in a dose-dependent manner (0.1 and 1.0 μM). Interestingly, both compounds had also significantly reduced the expression of adipogenic-related genes such as peroxisome proliferator-activated receptor γ2 (PPARγ2), CCAAT/enhancer-binding protein α (C/EBPα), adiponectin, and leptin in 3T3-L1 cells. The findings suggest that shinorine and porphyra-334 have the potential to inhibit adipogenesis in 3T3-L1 preadipocytes. |
| Author | Choi, Su-Young Kim, Hyung Gyun Jeong, Jae Cheon Lee, Su Yeon Batara, Don Carlo Cho, Jeong-Yong Kim, Sung-Hak |
| Author_xml | – sequence: 1 givenname: Su-Young surname: Choi fullname: Choi, Su-Young organization: Department of Animal Science, Chonnam National University – sequence: 2 givenname: Su Yeon surname: Lee fullname: Lee, Su Yeon organization: Department of Food Science and Technology, Chonnam National University – sequence: 3 givenname: Hyung Gyun surname: Kim fullname: Kim, Hyung Gyun organization: Mokpo Marine Food-Industry Research Center – sequence: 4 givenname: Jae Cheon surname: Jeong fullname: Jeong, Jae Cheon organization: Mokpo Marine Food-Industry Research Center – sequence: 5 givenname: Don Carlo surname: Batara fullname: Batara, Don Carlo organization: Department of Animal Science, Chonnam National University – sequence: 6 givenname: Sung-Hak orcidid: 0000-0003-4882-8600 surname: Kim fullname: Kim, Sung-Hak email: sunghakkim@jnu.ac.kr organization: Department of Animal Science, Chonnam National University – sequence: 7 givenname: Jeong-Yong surname: Cho fullname: Cho, Jeong-Yong email: jyongcho17@jnu.ac.kr organization: Department of Food Science and Technology, Chonnam National University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35529689$$D View this record in MEDLINE/PubMed https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002836830$$DAccess content in National Research Foundation of Korea (NRF) |
| BookMark | eNqNkktvEzEUhS1URNPCH2CBLLFpFwN-e7xBqqoClSKBIKwtZ-ZO4nZiB3tSqf8eTybl0UXFxleyv3N07_U5QUchBkDoNSXvKCH6fS6nqivCWEUokbJSz9CMEcMqJaQ6QjPKmKq0JvUxOsn5ptCUafECHXMpmVG1maHu-9qHmHwA7EKLtzFt1_fJVZwL7HPs3QAt7lLc4N7dQcJnXw8EbiEMbnDn2Ie1X_oBu9Zv4woCZJ_LJeYLXs0pbqDv80v0vHN9hleHeop-fLxaXH6u5l8-XV9ezKtGCjpUFITW1GjDJFGk1oJ2UPOOC22EYqYzwLgBoLVYag6UdAKEUwpYA1S3S8NP0fnkG1Jnbxtvo_P7uor2NtmLb4tra4zSlKrCfpjY7W65gbYp8yTX223yG5fu98p_X4JfF587awjnhpBicHYwSPHnDvJgNz6P47oAcZctU4qKmkul_wclpjZai4K-fYTexF0KZWuFksWNSTkavvm7-d9dP_xsAeoJaFLMOUFnG1_-y8dxFt9bSuwYIjuFyJYQ2X2I7LgY9kj64P6kiE-iXOCwgvSn7SdUvwCmPtZl |
| CitedBy_id | crossref_primary_10_3390_md20080478 crossref_primary_10_1016_j_ecoenv_2024_116122 crossref_primary_10_1128_aem_00740_23 crossref_primary_10_1016_j_algal_2024_103507 crossref_primary_10_1021_acs_jafc_2c07218 crossref_primary_10_1021_acs_jafc_4c05664 |
| Cites_doi | 10.1055/s-0035-1565472 10.1016/j.jphotobiol.2018.12.009 10.1007/s13679-016-0231-x 10.4093/dmj.2012.36.1.13 10.1021/acs.jafc.7b04688 10.3390/antiox8030074 10.2174/0929867324666170523120101 10.1038/sj.ijo.0802907 10.1016/j.metabol.2014.10.015 10.3389/fphar.2018.01366 10.1186/s41240-018-0095-y 10.1016/j.heliyon.2016.e00194 10.1002/2327-6924.12510 10.4162/nrp.2015.9.6.592 10.5187/jast.2020.62.6.854 10.1016/j.biochi.2018.07.020 10.3390/md17040222 10.4081/ejh.2013.e24 10.1002/cphy.c170046 10.3390/md9081359 10.3390/md12094732 10.1080/09168451.2014.912116 10.3390/ijms17040569 10.1007/BF00316069 10.1016/S1097-2765(00)80306-8 10.1016/B978-0-12-398313-8.00006-3 10.4103/0973-7847.91107 10.3390/md12105174 10.3390/nu11071562 10.1155/2015/534320 10.3390/md18100502 10.3390/md19050245 10.3390/md17090532 |
| ContentType | Journal Article |
| Copyright | The Korean Society of Food Science and Technology 2022 The Korean Society of Food Science and Technology 2022. |
| Copyright_xml | – notice: The Korean Society of Food Science and Technology 2022 – notice: The Korean Society of Food Science and Technology 2022. |
| DBID | AAYXX CITATION NPM 7S9 L.6 7X8 5PM ACYCR |
| DOI | 10.1007/s10068-022-01055-6 |
| DatabaseName | CrossRef PubMed AGRICOLA AGRICOLA - Academic MEDLINE - Academic PubMed Central (Full Participant titles) Korean Citation Index |
| DatabaseTitle | CrossRef PubMed AGRICOLA AGRICOLA - Academic MEDLINE - Academic |
| DatabaseTitleList | AGRICOLA PubMed MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Engineering Chemistry |
| EISSN | 2092-6456 |
| EndPage | 625 |
| ExternalDocumentID | oai_kci_go_kr_ARTI_9967116 PMC9033900 35529689 10_1007_s10068_022_01055_6 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: Ministry of Oceans and Fisheries and Mokpo Metropolitan City through the Capacity Building Project for the Development of Mokpo Seafood Industry-Based Complex grantid: B0080416003290 – fundername: National Research Foundation (NRF) funded by the Ministry of Science and ICT (MSIT), Republic of Korea grantid: 2019R1I1A3A01059211 – fundername: ; grantid: 2019R1I1A3A01059211 – fundername: ; grantid: B0080416003290 |
| GroupedDBID | -EM .UV 06D 0R~ 0VY 1N0 203 29H 2KG 2VQ 30V 4.4 406 408 40D 5GY 67Z 96X 9ZL AACDK AAHBH AAHNG AAIAL AAJBT AAJKR AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH AAZMS ABAKF ABDZT ABECU ABFTV ABJNI ABJOX ABKCH ABMQK ABQBU ABSXP ABTEG ABTHY ABTKH ABTMW ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACIWK ACKNC ACMDZ ACMLO ACOKC ACPIV ACZOJ ADBBV ADHHG ADHIR ADINQ ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFQL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETCA AEVLU AEXYK AFBBN AFLOW AFQWF AFRAH AFWTZ AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWZB AGYKE AHAVH AHBYD AHKAY AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ ALFXC ALMA_UNASSIGNED_HOLDINGS AMKLP AMXSW AMYLF AMYQR ANMIH AOCGG AOIJS AXYYD AYJHY BGNMA CAG COF CSCUP DBRKI DDRTE DNIVK DPUIP DU5 EBLON EBS EIOEI EJD ESBYG F5P FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FYJPI GGCAI GGRSB GJIRD GQ6 GQ7 GW5 H13 HF~ HG6 HMJXF HRMNR HYE HZ~ I0C IKXTQ IWAJR IXD J-C J0Z JBSCW JZLTJ KOV KVFHK LLZTM M1Z M4Y MZR NPVJJ NQJWS NU0 O9- O9J OK1 P2P P9N PT4 R9I RLLFE ROL RPM RSV S1Z S27 S3B SCM SDH SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW STPWE T13 TDB TSG U2A UG4 UOJIU UTJUX UZXMN VC2 VFIZW W48 WK8 Z45 Z7U Z7V Z7W ZMTXR ZZE ~A9 AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC AEZWR AFDZB AFHIU AFOHR AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION NPM ABRTQ 7S9 L.6 7X8 5PM 85H AAFGU AAPBV AAYFA ABFGW ABKAS ACBMV ACBRV ACBYP ACIGE ACIPQ ACTTH ACVWB ACWMK ACYCR ADMDM ADOXG AEFTE AESTI AEVTX AFNRJ AGGBP AIMYW AJDOV AKQUC SQXTU Z7Z Z83 |
| ID | FETCH-LOGICAL-c541t-1e4771979250608741fe83f34794629f9e239ee184b73e10f4e4a66e2ce17db93 |
| IEDL.DBID | U2A |
| ISSN | 1226-7708 2092-6456 |
| IngestDate | Tue Nov 21 21:31:56 EST 2023 Thu Aug 21 18:38:24 EDT 2025 Thu Jul 10 19:17:01 EDT 2025 Thu Jul 10 19:28:21 EDT 2025 Fri Jul 25 10:48:57 EDT 2025 Wed Feb 19 02:24:44 EST 2025 Tue Jul 01 04:26:28 EDT 2025 Thu Apr 24 23:03:14 EDT 2025 Fri Feb 21 02:46:14 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Laver Adipocyte differentiation Shinorine Porphyra-334 Adipogenesis Porphyra dentata |
| Language | English |
| License | The Korean Society of Food Science and Technology 2022. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c541t-1e4771979250608741fe83f34794629f9e239ee184b73e10f4e4a66e2ce17db93 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0003-4882-8600 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/9033900 |
| PMID | 35529689 |
| PQID | 2653562557 |
| PQPubID | 2043650 |
| PageCount | 9 |
| ParticipantIDs | nrf_kci_oai_kci_go_kr_ARTI_9967116 pubmedcentral_primary_oai_pubmedcentral_nih_gov_9033900 proquest_miscellaneous_2661483567 proquest_miscellaneous_2660989774 proquest_journals_2653562557 pubmed_primary_35529689 crossref_citationtrail_10_1007_s10068_022_01055_6 crossref_primary_10_1007_s10068_022_01055_6 springer_journals_10_1007_s10068_022_01055_6 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2022-05-01 |
| PublicationDateYYYYMMDD | 2022-05-01 |
| PublicationDate_xml | – month: 05 year: 2022 text: 2022-05-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Singapore |
| PublicationPlace_xml | – name: Singapore – name: Korea (South) – name: Heidelberg |
| PublicationTitle | Food science and biotechnology |
| PublicationTitleAbbrev | Food Sci Biotechnol |
| PublicationTitleAlternate | Food Sci Biotechnol |
| PublicationYear | 2022 |
| Publisher | Springer Nature Singapore Springer Nature B.V 한국식품과학회 |
| Publisher_xml | – name: Springer Nature Singapore – name: Springer Nature B.V – name: 한국식품과학회 |
| References | Fang, Judd (CR9) 2018; 8 Chuang, Chou, Sung (CR7) 2014; 12 Sáinz, Barrenetxe, Moreno-Aliaga, Martínez (CR29) 2015; 64 Fruh (CR11) 2017; 29 CR13 CR34 Bito, Teng, Watanabe (CR4) 2017; 65 Rui, Zhaohui, Wenshan, Bafang, Hu (CR28) 2019; 192 Choi, Lee, Jang, Lee, Cho, Kim (CR6) 2020; 62 Farmer (CR10) 2005; 29 Li, Gao, Yan, Zhang, Wang, Hu, Wu, Wang, Sheng (CR19) 2018; 9 Yang, Yang, Luo, Wei, Wang, Zhong (CR35) 2018; 17 Kim, Lee, Han, Choi (CR18) 2015; 9 Hartmann, Gostner, Fuchs, Chaita, Aligiannis, Skaltsounis, Ganzera (CR14) 2015; 81 Montero, Del Pilar, Ibáñez, Gilbert-López (CR21) 2018; 25 Kageyama, Waditee-Sirisattha (CR15) 2019; 17 Do Thi, Hwang (CR8) 2014; 78 Carpéné, Les, Cásedas, Peiro, Fontaine, Chaplin, Mercader, López (CR5) 2019; 8 Kang, Park (CR16) 2012; 36 Gacesa, Lawrence, Georgakopoulos, Yabe, Dunlap, Barlow, Wells, Young, Long (CR12) 2018; 154 Suh, Hwang, Park, Seo, Kim, Lee, Moh, Lee (CR31) 2014; 12 Bhatia, Garg, Sharma, Kumar, Sharma, Purohit (CR3) 2011; 5 CR24 CR22 Park, Jung, Roh (CR25) 2011; 9 CR20 Sanjeewa, Lee, Jeon (CR30) 2018; 21 Wu, Rosen, Brun, Hauser, Adelmant, Troy, McKeon, Darlington, Spiegelman (CR33) 1999; 3 Astapova, Leff (CR1) 2012; 90 Bell, Rahmouni (CR2) 2016; 5 Rizzatti, Boschi, Pedrotti, Zoico, Sbarbati, Zamboni (CR27) 2013; 57 Tsubai, Noda, Ito, Nakao, Seino, Oiso, Hamada (CR32) 2016; 2 Ramírez-Zacarías, Castro-Muñozledo, Kuri-Harcuch (CR26) 1992; 97 Kawser Hossain, Abdal Dayem, Han, Yin, Kim, Kumar Saha, Yang, Choi, Cho (CR17) 2016; 17 W Yang (1055_CR35) 2018; 17 Y Rui (1055_CR28) 2019; 192 V Rizzatti (1055_CR27) 2013; 57 N Sáinz (1055_CR29) 2015; 64 L Montero (1055_CR21) 2018; 25 A Hartmann (1055_CR14) 2015; 81 SM Fruh (1055_CR11) 2017; 29 JL Ramírez-Zacarías (1055_CR26) 1992; 97 S-S Suh (1055_CR31) 2014; 12 C Carpéné (1055_CR5) 2019; 8 Z Wu (1055_CR33) 1999; 3 1055_CR13 1055_CR34 N Do Thi (1055_CR8) 2014; 78 M Kawser Hossain (1055_CR17) 2016; 17 F Li (1055_CR19) 2018; 9 L-F Chuang (1055_CR7) 2014; 12 O Astapova (1055_CR1) 2012; 90 H Fang (1055_CR9) 2018; 8 KKA Sanjeewa (1055_CR30) 2018; 21 H Kim (1055_CR18) 2015; 9 1055_CR22 S-Y Choi (1055_CR6) 2020; 62 T Tsubai (1055_CR32) 2016; 2 1055_CR20 R Gacesa (1055_CR12) 2018; 154 M-K Park (1055_CR25) 2011; 9 JG Kang (1055_CR16) 2012; 36 1055_CR24 T Bito (1055_CR4) 2017; 65 BB Bell (1055_CR2) 2016; 5 S Bhatia (1055_CR3) 2011; 5 SR Farmer (1055_CR10) 2005; 29 H Kageyama (1055_CR15) 2019; 17 |
| References_xml | – volume: 81 start-page: 813 year: 2015 end-page: 820 ident: CR14 article-title: Inhibition of collagenase by mycosporine-like amino acids from marine sources publication-title: Planta Medica. doi: 10.1055/s-0035-1565472 – ident: CR22 – volume: 192 start-page: 26 year: 2019 end-page: 33 ident: CR28 article-title: Protective effect of maas extracted from against UV irradiation-induced photoaging in mouse skin publication-title: Journal of Photochemistry and Photobiology B: Biology. doi: 10.1016/j.jphotobiol.2018.12.009 – volume: 5 start-page: 397 year: 2016 end-page: 404 ident: CR2 article-title: Leptin as a mediator of obesity-induced hypertension publication-title: Curr Obes Rep doi: 10.1007/s13679-016-0231-x – volume: 36 start-page: 13 issue: 1 year: 2012 end-page: 25 ident: CR16 article-title: Anti-obesity drugs: A review about their effects and safety publication-title: Diabetes and Metabolism Journal doi: 10.4093/dmj.2012.36.1.13 – volume: 65 start-page: 10685 year: 2017 end-page: 10692 ident: CR4 article-title: Bioactive compounds of edible purple laver sp. (Nori) publication-title: Journal of Agricultural and Food Chemistry doi: 10.1021/acs.jafc.7b04688 – volume: 8 start-page: 74 year: 2019 ident: CR5 article-title: Resveratrol anti-obesity effects: rapid inhibition of adipocyte glucose utilization publication-title: Antioxidants (Basel) doi: 10.3390/antiox8030074 – volume: 25 start-page: 4808 year: 2018 end-page: 4826 ident: CR21 article-title: Phenolic compounds from edible algae: bioactivity and health benefits publication-title: Current Medicinal Chemistry. doi: 10.2174/0929867324666170523120101 – volume: 29 start-page: S13 year: 2005 end-page: S16 ident: CR10 article-title: Regulation of PPARγ activity during adipogenesis publication-title: International Journal of Obesity. doi: 10.1038/sj.ijo.0802907 – volume: 64 start-page: 35 issue: 1 year: 2015 end-page: 46 ident: CR29 article-title: Leptin resistance and diet-induced obesity: central and peripheral actions of leptin publication-title: Metabolism: Clinical and Experimental doi: 10.1016/j.metabol.2014.10.015 – volume: 9 start-page: 1366 year: 2018 ident: CR19 article-title: EGCG Reduces obesity and white adipose tissue gain partly through AMPK activation in mice publication-title: Frontiers in Pharmacology. doi: 10.3389/fphar.2018.01366 – volume: 21 start-page: 19 issue: 1 year: 2018 ident: CR30 article-title: Nutrients and bioactive potentials of edible green and red seaweed in Korea publication-title: Fisheries and Aquatic Sciences. doi: 10.1186/s41240-018-0095-y – volume: 2 start-page: e00194 year: 2016 ident: CR32 article-title: Insulin elevates leptin secretion and mRNA levels via cyclic AMP in 3T3-L1 adipocytes deprived of glucose publication-title: Heliyon. doi: 10.1016/j.heliyon.2016.e00194 – volume: 17 start-page: 428 issue: 1 year: 2018 end-page: 435 ident: CR35 article-title: Adiponectin promotes preadipocyte differentiation via the PPARγ pathway publication-title: Molecular Medicine Reports. – volume: 29 start-page: S3 year: 2017 end-page: S14 ident: CR11 article-title: Obesity: Risk factors, complications, and strategies for sustainable long-term weight management publication-title: Journal of the American Association of Nurse Practitioners. doi: 10.1002/2327-6924.12510 – volume: 9 start-page: 592 year: 2015 end-page: 598 ident: CR18 article-title: (a) The micosporine-like amino acids-rich aqueous methanol extract of laver ( ) inhibits adipogenesis and induces apoptosis in 3T3-L1 adipocytes publication-title: Nutrition Research and Practice doi: 10.4162/nrp.2015.9.6.592 – volume: 62 start-page: 854 year: 2020 end-page: 863 ident: CR6 article-title: inhibitory effects of extract on 3T3-L1 adipocyte differentiation publication-title: Journal of Animal Science and Technology. doi: 10.5187/jast.2020.62.6.854 – volume: 154 start-page: 35 year: 2018 end-page: 44 ident: CR12 article-title: The mycosporine-like amino acids porphyra-334 and shinorine are antioxidants and direct antagonists of Keap1-Nrf2 binding publication-title: Biochimie. doi: 10.1016/j.biochi.2018.07.020 – volume: 17 start-page: 222 year: 2019 ident: CR15 article-title: Antioxidative, Anti-Inflammatory, and Anti-Aging Properties of mycosporine-like amino acids: molecular and cellular mechanisms in the protection of skin-aging publication-title: Marine Drugs doi: 10.3390/md17040222 – volume: 57 start-page: 159 year: 2013 end-page: 162 ident: CR27 article-title: Lipid droplets characterization in adipocyte differentiated 3T3-L1 cells: Size and optical density distribution publication-title: European Journal of Histochemistry. doi: 10.4081/ejh.2013.e24 – volume: 8 start-page: 1031 year: 2018 end-page: 1063 ident: CR9 article-title: Adiponectin regulation and function publication-title: Comprehensive Physiology. doi: 10.1002/cphy.c170046 – volume: 9 start-page: 1359 year: 2011 end-page: 1367 ident: CR25 article-title: Fucoidan from marine brown algae inhibits lipid accumulation publication-title: Marine Drugs. doi: 10.3390/md9081359 – volume: 12 start-page: 4732 year: 2014 end-page: 4740 ident: CR7 article-title: Porphyra-334 isolated from the marine algae : conformational performance for energy conversion publication-title: Marine Drugs. doi: 10.3390/md12094732 – volume: 78 start-page: 1044 year: 2014 end-page: 1051 ident: CR8 article-title: Effects of laver extracts on adhesion, invasion, and migration in SK-Hep1 human hepatoma cancer cells publication-title: Bioscience, Biotechnology, and Biochemistry. doi: 10.1080/09168451.2014.912116 – volume: 17 start-page: 569 year: 2016 ident: CR17 article-title: Molecular mechanisms of the anti-obesity and anti-diabetic properties of flavonoids publication-title: International Journal of Molecular Sciences. doi: 10.3390/ijms17040569 – volume: 97 start-page: 493 issue: 6 year: 1992 end-page: 497 ident: CR26 article-title: Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O publication-title: Histochemistry. doi: 10.1007/BF00316069 – ident: CR13 – volume: 3 start-page: 151 year: 1999 end-page: 158 ident: CR33 article-title: Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity publication-title: Molecular Cell. doi: 10.1016/S1097-2765(00)80306-8 – volume: 90 start-page: 143 year: 2012 end-page: 162 ident: CR1 article-title: Adiponectin and PPARγ: cooperative and interdependent actions of two key regulators of metabolism publication-title: Vitam Horm doi: 10.1016/B978-0-12-398313-8.00006-3 – volume: 5 start-page: 138 year: 2011 end-page: 146 ident: CR3 article-title: Mycosporine and mycosporine-like amino acids: a paramount tool against ultraviolet irradiation publication-title: Pharmacognosy Reviews. doi: 10.4103/0973-7847.91107 – ident: CR34 – ident: CR24 – ident: CR20 – volume: 12 start-page: 5174 year: 2014 end-page: 5187 ident: CR31 article-title: Anti-inflammation activities of mycosporine-like amino acids (MAAs) in response to UV radiation suggest potential anti-skin aging activity publication-title: Marine Drugs. doi: 10.3390/md12105174 – volume: 29 start-page: S3 year: 2017 ident: 1055_CR11 publication-title: Journal of the American Association of Nurse Practitioners. doi: 10.1002/2327-6924.12510 – volume: 29 start-page: S13 year: 2005 ident: 1055_CR10 publication-title: International Journal of Obesity. doi: 10.1038/sj.ijo.0802907 – volume: 12 start-page: 5174 year: 2014 ident: 1055_CR31 publication-title: Marine Drugs. doi: 10.3390/md12105174 – volume: 3 start-page: 151 year: 1999 ident: 1055_CR33 publication-title: Molecular Cell. doi: 10.1016/S1097-2765(00)80306-8 – volume: 97 start-page: 493 issue: 6 year: 1992 ident: 1055_CR26 publication-title: Histochemistry. doi: 10.1007/BF00316069 – volume: 2 start-page: e00194 year: 2016 ident: 1055_CR32 publication-title: Heliyon. doi: 10.1016/j.heliyon.2016.e00194 – volume: 25 start-page: 4808 year: 2018 ident: 1055_CR21 publication-title: Current Medicinal Chemistry. doi: 10.2174/0929867324666170523120101 – ident: 1055_CR22 doi: 10.3390/nu11071562 – volume: 65 start-page: 10685 year: 2017 ident: 1055_CR4 publication-title: Journal of Agricultural and Food Chemistry doi: 10.1021/acs.jafc.7b04688 – volume: 17 start-page: 428 issue: 1 year: 2018 ident: 1055_CR35 publication-title: Molecular Medicine Reports. – volume: 154 start-page: 35 year: 2018 ident: 1055_CR12 publication-title: Biochimie. doi: 10.1016/j.biochi.2018.07.020 – volume: 9 start-page: 592 year: 2015 ident: 1055_CR18 publication-title: Nutrition Research and Practice doi: 10.4162/nrp.2015.9.6.592 – volume: 8 start-page: 74 year: 2019 ident: 1055_CR5 publication-title: Antioxidants (Basel) doi: 10.3390/antiox8030074 – volume: 8 start-page: 1031 year: 2018 ident: 1055_CR9 publication-title: Comprehensive Physiology. doi: 10.1002/cphy.c170046 – volume: 36 start-page: 13 issue: 1 year: 2012 ident: 1055_CR16 publication-title: Diabetes and Metabolism Journal doi: 10.4093/dmj.2012.36.1.13 – ident: 1055_CR13 doi: 10.1155/2015/534320 – volume: 9 start-page: 1366 year: 2018 ident: 1055_CR19 publication-title: Frontiers in Pharmacology. doi: 10.3389/fphar.2018.01366 – ident: 1055_CR24 doi: 10.3390/md18100502 – volume: 9 start-page: 1359 year: 2011 ident: 1055_CR25 publication-title: Marine Drugs. doi: 10.3390/md9081359 – volume: 5 start-page: 397 year: 2016 ident: 1055_CR2 publication-title: Curr Obes Rep doi: 10.1007/s13679-016-0231-x – volume: 17 start-page: 222 year: 2019 ident: 1055_CR15 publication-title: Marine Drugs doi: 10.3390/md17040222 – volume: 21 start-page: 19 issue: 1 year: 2018 ident: 1055_CR30 publication-title: Fisheries and Aquatic Sciences. doi: 10.1186/s41240-018-0095-y – volume: 64 start-page: 35 issue: 1 year: 2015 ident: 1055_CR29 publication-title: Metabolism: Clinical and Experimental doi: 10.1016/j.metabol.2014.10.015 – volume: 57 start-page: 159 year: 2013 ident: 1055_CR27 publication-title: European Journal of Histochemistry. doi: 10.4081/ejh.2013.e24 – volume: 17 start-page: 569 year: 2016 ident: 1055_CR17 publication-title: International Journal of Molecular Sciences. doi: 10.3390/ijms17040569 – ident: 1055_CR20 doi: 10.3390/md19050245 – volume: 5 start-page: 138 year: 2011 ident: 1055_CR3 publication-title: Pharmacognosy Reviews. doi: 10.4103/0973-7847.91107 – volume: 62 start-page: 854 year: 2020 ident: 1055_CR6 publication-title: Journal of Animal Science and Technology. doi: 10.5187/jast.2020.62.6.854 – volume: 12 start-page: 4732 year: 2014 ident: 1055_CR7 publication-title: Marine Drugs. doi: 10.3390/md12094732 – volume: 78 start-page: 1044 year: 2014 ident: 1055_CR8 publication-title: Bioscience, Biotechnology, and Biochemistry. doi: 10.1080/09168451.2014.912116 – ident: 1055_CR34 doi: 10.3390/md17090532 – volume: 81 start-page: 813 year: 2015 ident: 1055_CR14 publication-title: Planta Medica. doi: 10.1055/s-0035-1565472 – volume: 90 start-page: 143 year: 2012 ident: 1055_CR1 publication-title: Vitam Horm doi: 10.1016/B978-0-12-398313-8.00006-3 – volume: 192 start-page: 26 year: 2019 ident: 1055_CR28 publication-title: Journal of Photochemistry and Photobiology B: Biology. doi: 10.1016/j.jphotobiol.2018.12.009 |
| SSID | ssj0061274 |
| Score | 2.304845 |
| Snippet | Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from
Porphyra
spp. are bioactive compounds with strong photoprotective and antioxidant... Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from spp. are bioactive compounds with strong photoprotective and antioxidant... Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant... |
| SourceID | nrf pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 617 |
| SubjectTerms | Adipocytes Adipogenesis Adiponectin Amino acids Antioxidants Bioactive compounds biotechnology CCAAT/enhancer-binding protein Chemistry Chemistry and Materials Science Cytotoxicity dose response edible seaweed Food Science Gene expression Leptin Lipids Magnetic resonance spectroscopy Mycosporine-like amino acids NMR NMR spectroscopy Nuclear magnetic resonance nuclear magnetic resonance spectroscopy Nutrition Porphyra Preadipocytes radiation resistance Research Article Shinorine 식품과학 |
| Title | Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells |
| URI | https://link.springer.com/article/10.1007/s10068-022-01055-6 https://www.ncbi.nlm.nih.gov/pubmed/35529689 https://www.proquest.com/docview/2653562557 https://www.proquest.com/docview/2660989774 https://www.proquest.com/docview/2661483567 https://pubmed.ncbi.nlm.nih.gov/PMC9033900 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002836830 |
| Volume | 31 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | Food Science and Biotechnology, 2022, 31(5), , pp.617-625 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1Lb9QwELb6OACHqi1QUsrKIA4gsBTbsR0fV1VLeQqJrlROlpNMulGrbLW7_f-Mvcm2W0olTpGSiWXNjO1v7JnPhLwVoiiE94oViDZYVirDbM6BFdpY5esKg65Q4Pz9hz4ZZV_O1FlXFDbrs937I8k4U98qdkt1zkL2ebzVkel1sqlC7I5ePBLDfv7FJTtyL3MEFogd07wrlbm_jZXlaL2d1vchzb8TJu-cmsbF6HibbHUokg4XZt8ha9DukkeH_eVtu-TJLZ7Bp6T-NW7akGkH1LcVRciNyp16JmVGG3Q-xJsVDYUm9NKja9N3PzsJWsXSJP-eNu24KZo59VVzNTkPE2Qzw5dUnkr2jdOw_z97RkbHR6eHJ6y7YIGVKuNzxiEzhltjRaAZzBFc1JDLWkbWeWFrC0JaAAwCCyOBp3UGmdcaRAncVIWVz8lGO2nhBaEGG0pB44xQlChTWwUp4NJXQp5z5SEhvNezKzv28XAJxqW74U0OtnFoGxdt43RCPiz_uVpwbzwo_QbN5y7KxgXK7PA8n7iLqcPA4LPDsM5wjkIHvXVdN1hnTmglQxyoTEJeLz-jwYLufAuT6yCjU5sHsPygDAaX2BS2s7dwmGW_EdYJq3ObELPiSkuB0OfVL20zjnTfNpXSpmlCPvZOd9P1f6tj___EX5LHIg6LkMp5QDbm02t4hXBrXgzI5vDT769Hg7gTNohj7Q_uwiAV |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3db9MwELfY9jB4QGx8BTYwiAcQWIrtxB-P07Spg25CopX2ZjnJZY02pVPb_f-c3aRbYUziKVJ8say7s_27-O5nQj4JURTC-5wViDZYVuaaWcOBFUrb3NcVBl2hwPn0TA3G2ffz_LwrCpv32e79kWRcqe8Uu6XKsJB9Hm91ZGqDbCEYMCGRaywO-vUXt-zIvcwRWCB2TE1XKnN_H2vb0UY7q-9Dmn8nTP5xaho3o-Nn5GmHIunB0uw75BG0u2T7sL-8bZc8ucMz-JzUvyZNGzLtgPq2ogi5Ubkzz6TMaIPOh3izoqHQhF55dG36-WcnQatYmuS_0KadNEWzoL5qrqcXYYFs5viSypFkQ07D___5CzI-PhodDlh3wQIr84wvGIdMa261FYFm0CC4qMHIWkbWeWFrC0JaAAwCCy2Bp3UGmVcKRAlcV4WVL8lmO23hNaEaO0pB4YpQlChT2xxSwK2vBGN47iEhvNezKzv28XAJxpW75U0OtnFoGxdt41RCvq6-uV5ybzwo_RHN5y7LxgXK7PC8mLrLmcPA4MRhWKc5R6G93rqum6xzJ1QuQxyY64R8WDWjwYLufAvTmyCjUmsCWH5QBoNL7Ar7ebV0mNW4EdYJq4xNiF5zpZVAGPN6S9tMIt23TaW0aZqQb73T3Q793-p483_i78n2YHQ6dMOTsx9vyWMRp0hI69wjm4vZDewj9FoU7-JM-w3gSSBk |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3db9MwELfYkPh4QDC-CgMM4gE0rMV2YseP06DaYEyTWKW9WU5yWaNNbtVm_z9nN-laGJN4ipRcLMt3vvudfPczIR-FKArhXMYKRBssLTPNTM6BFUqbzNUVJl2hwfnnsToYpd_PsrOVLv5Y7d4fSS56GgJLk293p1W9u9L4lqichUr0eMMjUxvkLrpjHux6JPZ6X4zhO_IwcwQZiCOTvGubuXmMtdC04Wf1Tajz7-LJP05QY2AaPiaPOkRJ9xYm8ITcAb9F7u_3F7ltkYcrnINPSf1r3PhQdQfU-Yoi_MaFnjkmZUobNETEnhUNTSf00qGZ008nnQStYpuS-0wbP26KpqWuaqaT8-Asmzm-pPJUsiNOw1nA_BkZDb-d7h-w7rIFVmYpbxmHVGtutBGBcjBHoFFDLmsZGeiFqQ0IaQAwISy0BJ7UKaROKRAlcF0VRj4nm37i4SWhGgdKQKF3KEqUqU0GCWAYLCHPeeZgQHi_zrbsmMjDhRiX9ppDOejGom5s1I1VA7Kz_Ge64OG4VfoDqs9elI0N9NnheT6xFzOLScKhxRRPc45C2712bbdx51aoTIacMNMD8n75GRUW1s55mFwFGZWYPADnW2Uw0cShcJwXC4NZzhshnjAqNwOi10xpKRDmvP7FN-NI_W0SKU2SDMiX3uiup_7v5Xj1f-LvyL2Tr0N7dHj84zV5IOIOCRWe22SznV3BG0RhbfE2brTfTDIkoA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Shinorine+and+porphyra-334+isolated+from+laver+%28Porphyra+dentata%29+inhibit+adipogenesis+in+3T3-L1+cells&rft.jtitle=Food+science+and+biotechnology&rft.au=Choi%2C+Su-Young&rft.au=Lee%2C+Su+Yeon&rft.au=Kim%2C+Hyung+Gyun&rft.au=Jeong%2C+Jae+Cheon&rft.date=2022-05-01&rft.pub=Springer+Nature+Singapore&rft.issn=1226-7708&rft.eissn=2092-6456&rft.volume=31&rft.issue=5&rft.spage=617&rft.epage=625&rft_id=info:doi/10.1007%2Fs10068-022-01055-6&rft.externalDocID=10_1007_s10068_022_01055_6 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1226-7708&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1226-7708&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1226-7708&client=summon |