Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis
Background Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age. Objectives In the present study, we sought evidence for...
Saved in:
| Published in | Psychopharmacologia Vol. 208; no. 4; pp. 531 - 543 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Berlin/Heidelberg
Springer-Verlag
01.03.2010
Springer Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0033-3158 1432-2072 1432-2072 |
| DOI | 10.1007/s00213-009-1754-6 |
Cover
Loading…
| Abstract | Background
Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age.
Objectives
In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis.
Methods
This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic–polyribocytidilic acid (PolyI:C).
Results
We found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis.
Conclusions
Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. |
|---|---|
| AbstractList | Background
Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age.
Objectives
In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis.
Methods
This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic–polyribocytidilic acid (PolyI:C).
Results
We found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis.
Conclusions
Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. Background: Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age. Objectives: In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis. Methods: This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyI:C). Results: We found that maternal PolyI:C (5mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3weeks) administration of clozapine (5mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis. Conclusions: Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age.BACKGROUNDConverging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age.In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis.OBJECTIVESIn the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis.This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyI:C).METHODSThis hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyI:C).We found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis.RESULTSWe found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis.Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology.CONCLUSIONSOur findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age. In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis. This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyI:C). We found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis. Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. [PUBLICATION ABSTRACT] Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive impairments may be related to deficient hippocampal neurogenesis at adult age. In the present study, we sought evidence for the possibility that chronic treatment with the reference atypical antipsychotic drug clozapine may improve prenatal infection-induced cognitive dysfunctions by stimulating adult hippocampal neurogenesis. This hypothesis was tested in a well-established mouse model of prenatal immune challenge which is based on prenatal administration of the viral mimic, polyriboinosinic-polyribocytidilic acid (PolyI:C). We found that maternal PolyI:C (5 mg/kg, i.v.) exposure on gestation day 17 led to significant spatial working memory impairment and reduced hippocampal neurogenesis in the resulting offspring at adult age. The latter effect was apparent in postmortem immunohistochemical analyses of the cell proliferation marker bromodeoxyuridine and the microtubule-associated protein doublecortin, a marker of newborn neuronal cells. Chronic (3 weeks) administration of clozapine (5 mg/kg/day, i.p.) significantly improved the prenatal PolyI:C-induced working memory deficits, while at the same time, it negatively affected working memory performance in adult offspring born to control mothers. These bidirectional cognitive effects of clozapine were not paralleled by concomitant effects on adult hippocampal neurogenesis. Our findings do not support the hypothesis that the atypical antipsychotic drug clozapine may influence cognitive functions by acting on adult neurogenesis in the hippocampus, regardless of whether the drug is administered to subjects with or without a neurodevelopmental predisposition to adult neuropathology. |
| Author | Nyffeler, Myriel Feldon, Joram Meyer, Urs Knuesel, Irene |
| Author_xml | – sequence: 1 givenname: Urs surname: Meyer fullname: Meyer, Urs email: urmeyer@ethz.ch organization: Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology (ETH) Zurich – sequence: 2 givenname: Irene surname: Knuesel fullname: Knuesel, Irene organization: Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology (ETH) Zurich, Institute of Pharmacology and Toxicology, University of Zurich – sequence: 3 givenname: Myriel surname: Nyffeler fullname: Nyffeler, Myriel organization: Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology (ETH) Zurich – sequence: 4 givenname: Joram surname: Feldon fullname: Feldon, Joram organization: Laboratory of Behavioural Neurobiology, Swiss Federal Institute of Technology (ETH) Zurich |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22393388$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20041229$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFks2KFDEUhYOMOD2jD-BGCkFclea_qpbS-AcDbnQd0slNd8aqpExSDuMj-NSm6B4GBtRsksV3bjjnngt0FmIAhJ4T_IZg3L3NGFPCWoyHlnSCt_IR2hDOaEtxR8_QBmPGWkZEf44ucr7G9fCeP0HntD4IpcMG_d4eUgzeNGaMv_TsAzQlgS4ThNL4aU7xJ-RmThB00WPjgwNTfAytD3YxYJubmL77sG8mmGK6bSw4b3zJzY0vh7iUVTEuEMzKaLuMpTn4eY5GT3OdF2BJcQ8Bss9P0WOnxwzPTvcl-vbh_dftp_bqy8fP23dXrRGclJZIwaxxg5WSCud2O9ILDYNjg2aD7B3nWgMWhFopdtpoI8AQTsGKHbUdduwSvT7OreZ-LJCLmnw2MI46QFyy6risMXUC_59knEoysL6SLx-Q13FJodpQlPSD7Lqhq9CLE7TsJrBqTn7S6VbdbaMCr06AzkaPLumaW77nKBsY69ffuiNnUsw5gVM1cr2upSTtR0WwWvuhjv1QtR9q7YeSVUkeKO-G_0tDj5pc2bCHdO_t76I_ef7Pvg |
| CODEN | PSYPAG |
| CitedBy_id | crossref_primary_10_1016_j_psychres_2017_10_018 crossref_primary_10_1007_s12021_010_9081_y crossref_primary_10_1016_j_schres_2015_05_010 crossref_primary_10_1016_j_neuropharm_2011_01_009 crossref_primary_10_3389_fphar_2021_682602 crossref_primary_10_1016_j_bbi_2016_12_003 crossref_primary_10_7717_peerj_2976 crossref_primary_10_1016_j_schres_2011_12_016 crossref_primary_10_1016_j_bbr_2011_07_033 crossref_primary_10_3389_fnsyn_2018_00031 crossref_primary_10_1016_j_ijdevneu_2017_01_009 crossref_primary_10_1007_s11434_013_5886_z crossref_primary_10_1016_j_bbi_2015_03_012 crossref_primary_10_1038_npp_2010_129 crossref_primary_10_1523_JNEUROSCI_4230_10_2011 crossref_primary_10_1002_hipo_20900 crossref_primary_10_1016_j_pharmthera_2015_01_001 crossref_primary_10_1016_j_pbb_2022_173453 crossref_primary_10_1016_j_pbb_2023_173593 crossref_primary_10_1016_j_bbr_2016_08_048 crossref_primary_10_1038_npp_2014_230 crossref_primary_10_1016_j_pharep_2015_04_014 crossref_primary_10_1016_j_bbi_2011_11_004 crossref_primary_10_3389_fpsyt_2020_00852 crossref_primary_10_1021_acs_jafc_7b03945 crossref_primary_10_1155_2012_832757 crossref_primary_10_1016_j_bbi_2014_01_019 crossref_primary_10_1016_j_pneurobio_2013_12_006 crossref_primary_10_1007_s00213_010_2035_0 crossref_primary_10_1080_17460441_2020_1682994 crossref_primary_10_1038_tp_2012_6 crossref_primary_10_1016_j_neubiorev_2020_04_012 crossref_primary_10_1007_s00213_012_2845_3 crossref_primary_10_1007_s11064_012_0768_3 crossref_primary_10_1016_j_bbi_2010_10_014 crossref_primary_10_1016_j_pnpbp_2011_11_003 crossref_primary_10_1016_j_pnpbp_2012_02_001 crossref_primary_10_1038_tp_2015_191 crossref_primary_10_1016_j_neures_2022_09_007 crossref_primary_10_1016_j_pnpbp_2016_04_008 crossref_primary_10_1016_j_bbr_2012_03_036 crossref_primary_10_1038_srep36087 crossref_primary_10_1016_j_brainres_2023_148446 crossref_primary_10_1016_j_cpr_2019_101748 crossref_primary_10_1016_j_euroneuro_2016_12_001 crossref_primary_10_1016_j_bbr_2019_112247 crossref_primary_10_1007_s00441_013_1692_9 crossref_primary_10_1016_j_nlm_2017_04_005 crossref_primary_10_1096_fj_14_258228 crossref_primary_10_1016_j_pnpbp_2016_01_005 crossref_primary_10_1016_j_brs_2012_09_004 crossref_primary_10_1080_15592294_2015_1114202 crossref_primary_10_1101_lm_031351_113 crossref_primary_10_1016_j_neuroscience_2015_04_065 crossref_primary_10_1016_j_nbd_2012_10_025 crossref_primary_10_1038_mp_2017_52 crossref_primary_10_1002_hipo_22193 crossref_primary_10_1007_s00213_020_05700_y crossref_primary_10_1016_j_schres_2013_06_001 crossref_primary_10_1093_ijnp_pyu055 crossref_primary_10_1016_j_bbi_2012_07_008 crossref_primary_10_1016_j_bbi_2014_10_010 crossref_primary_10_1016_j_neuropharm_2016_12_025 crossref_primary_10_1016_j_bbi_2015_09_015 crossref_primary_10_1111_jnc_16212 crossref_primary_10_1016_j_bbr_2021_113145 crossref_primary_10_1016_j_tig_2022_03_006 crossref_primary_10_1038_s41398_021_01762_4 crossref_primary_10_1016_j_pneurobio_2018_12_002 crossref_primary_10_1016_j_jri_2014_03_005 crossref_primary_10_1038_tp_2015_129 |
| Cites_doi | 10.1016/S0006-3223(98)00331-X 10.1037/0735-7044.113.5.941 10.1016/j.schres.2009.05.003 10.1093/schbul/sbj052 10.1002/cne.10874 10.1007/s00213-003-1761-y 10.1016/j.tins.2004.05.013 10.1523/JNEUROSCI.0099-06.2006 10.1016/j.bbr.2008.12.022 10.1002/hipo.1077 10.1037/0735-7044.122.1.16 10.1016/S0896-6273(00)80777-1 10.1016/j.biopsych.2005.07.031 10.1016/S0306-4522(01)00171-3 10.1177/1073858406296401 10.1016/j.schres.2006.09.030 10.1016/j.jpsychires.2004.08.008 10.1016/j.euroneuro.2005.03.001 10.1111/j.1460-9568.2005.04386.x 10.1126/science.1135801 10.1254/jphs.FP0061424 10.1016/j.schres.2003.12.002 10.1126/science.1173215 10.1111/j.1460-9568.2004.03813.x 10.1093/schbul/sbn022 10.1055/s-2002-34120 10.1016/j.neubiorev.2004.03.004 10.1038/4151030a 10.1016/S0079-6123(07)63010-6 10.1038/sj.mp.4001791 10.1016/S0920-9964(96)00123-5 10.1002/(SICI)1098-1063(1999)9:2<118::AID-HIPO4>3.0.CO;2-8 10.1038/sj.npp.1300669 10.1016/j.bbr.2008.12.016 10.1126/science.1150196 10.1037/0735-7044.100.6.852 10.1016/j.neubiorev.2008.08.007 10.1097/YCO.0b013e3282fad375 10.1016/j.neubiorev.2004.10.012 10.1007/s00213-006-0416-1 10.1038/sj.npp.1300248 10.1038/mp.2009.75 10.1016/S0959-4388(02)00299-4 10.1016/S0079-6123(00)26008-1 10.1016/0028-3932(79)90042-3 10.1038/mp.2008.119 10.1007/s00406-007-0733-3 10.1038/nrn1201 10.1016/0006-3223(93)90043-D 10.1016/S0079-6123(07)63030-1 10.1002/(SICI)1096-9861(19980112)390:2<194::AID-CNE3>3.0.CO;2-X 10.1176/appi.ajp.2008.08010089 10.1016/j.bbi.2007.09.012 10.1007/s00213-003-1506-y 10.1038/sj.npp.1300422 10.1016/S0920-9964(98)00145-5 10.1016/j.bbr.2008.08.022 10.1038/207953a0 10.1002/mrdd.10004 10.1016/S0165-1781(97)00062-0 10.1016/j.neubiorev.2009.05.001 10.1093/brain/122.4.593 10.1007/s00702-003-0070-2 10.1016/j.neuroscience.2008.04.031 10.1176/appi.ajp.162.5.1013 10.1038/mp.2009.66 10.1152/ajpregu.00268.2005 10.1523/JNEUROSCI.13-09-03916.1993 10.1385/NI:5:1:79 10.1523/JNEUROSCI.18-02-00804.1998 10.1007/BF02389022 10.1176/ps.47.1.41 10.1523/JNEUROSCI.23-01-00297.2003 10.1093/oxfordjournals.schbul.a033325 10.3109/9780203007648 10.1523/JNEUROSCI.23-04-01517.2003 |
| ContentType | Journal Article |
| Copyright | Springer-Verlag 2009 2015 INIST-CNRS Springer-Verlag 2010 |
| Copyright_xml | – notice: Springer-Verlag 2009 – notice: 2015 INIST-CNRS – notice: Springer-Verlag 2010 |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 3V. 7QG 7QR 7RV 7TK 7X7 7XB 88E 88G 8AO 8FD 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ K9. KB0 M0S M1P M2M NAPCQ P64 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 7U9 H94 |
| DOI | 10.1007/s00213-009-1754-6 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Animal Behavior Abstracts Chemoreception Abstracts Nursing & Allied Health Database Neurosciences Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Technology Research Database ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Local Electronic Collection Information ProQuest Central ProQuest One Community College ProQuest Central Korea Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Health & Medical Collection Medical Database Psychology Database Nursing & Allied Health Premium Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic Virology and AIDS Abstracts AIDS and Cancer Research Abstracts |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student Technology Research Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection Chemoreception Abstracts ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition Animal Behavior Abstracts ProQuest Nursing & Allied Health Source (Alumni) Engineering Research Database ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic AIDS and Cancer Research Abstracts Virology and AIDS Abstracts |
| DatabaseTitleList | AIDS and Cancer Research Abstracts MEDLINE - Academic ProQuest One Psychology MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1432-2072 |
| EndPage | 543 |
| ExternalDocumentID | 1951085031 20041229 22393388 10_1007_s00213_009_1754_6 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GroupedDBID | -4W -BR .55 3SX 40D 40E 95. 95~ ABMNI AGWIL ALMA_UNASSIGNED_HOLDINGS KOW N2Q R9- RHV SBY SOJ X7M ~EX AAYXX CITATION IQODW --- -Y2 .86 .GJ .VR 04C 06C 06D 0R~ 0VY 123 199 1N0 1SB 2.D 203 28- 29P 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2QV 2VQ 2~H 30V 36B 3O- 4.4 406 408 409 53G 5QI 5RE 5VS 67N 67Z 6NX 78A 7RV 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AAPKM AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDBE ABDBF ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABIVO ABJNI ABJOX ABKCH ABKTR ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTAH ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHXU ACIWK ACKNC ACMDZ ACMLO ACNCT ACOKC ACOMO ACPIV ACPRK ACUHS ACZOJ ADBBV ADHHG ADHIR ADHKG ADIMF ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADYPR ADZKW AEBTG AEFIE AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFEXP AFFNX AFGCZ AFKRA AFLOW AFQWF AFRAH AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHPBZ AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AYFIA AZFZN AZQEC B-. B0M BA0 BBWZM BDATZ BENPR BGNMA BKEYQ BMSDO BPHCQ BSONS BVXVI CAG CCPQU CGR COF CS3 CSCUP CUY CVF DDRTE DL5 DNIVK DPUIP DU5 DWQXO DXH EAD EAP EBC EBD EBLON EBS ECM EIF EIHBH EIOEI EJD EMB EMK EMOBN EN4 EPAXT EPL EPS ESBYG ESX EX3 F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ7 GQ8 GXS H13 HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IAO ICJ IHE IHR IJ- IKXTQ IMOTQ INH INR IPY ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KPH LAS LLZTM M1P M2M M4Y MA- MK0 N9A NAPCQ NB0 NDZJH NPM NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM P19 P2P PF- PHGZT PQQKQ PROAC PSQYO PSYQQ PT4 PT5 Q2X QOK QOR QOS R4E R89 R9I RIG RNI ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S3A S3B SAP SBL SCLPG SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 T16 TN5 TSG TSK TSV TUC TUS U2A U9L UAP UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WH7 WIP WJK WK6 WK8 WOW XOL YLTOR YQJ YYP Z45 ZGI ZMTXR ZOVNA ZY4 ~8M 3V. 7QG 7QR 7TK 7XB 8FD 8FK FR3 K9. P64 PHGZM PJZUB PKEHL PPXIY PQEST PQUKI PRINS Q9U 7X8 ABBRH ABFSG ABRTQ ACSTC AEZWR AFDZB AFHIU AGQPQ AHWEU AIXLP ATHPR PUEGO 7U9 H94 |
| ID | FETCH-LOGICAL-c541t-1653dcf9d6625ffbb185ae9f39a3968f44aae0512d65bacac5ec142ed5b2d70f3 |
| IEDL.DBID | BENPR |
| ISSN | 0033-3158 1432-2072 |
| IngestDate | Fri Jul 11 08:41:07 EDT 2025 Fri Sep 05 09:53:19 EDT 2025 Sat Aug 16 21:44:25 EDT 2025 Thu Apr 03 06:56:15 EDT 2025 Wed Apr 02 07:25:59 EDT 2025 Tue Jul 01 04:16:36 EDT 2025 Thu Apr 24 22:58:14 EDT 2025 Fri Feb 21 02:33:24 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Keywords | Infection Schizophrenia Animal model Cognition Antipsychotic drugs Hippocampus Memory disorder Dibenzodiazepine derivatives Cognitive disorder Atypical antipsychotic Neuroleptic Psychotropic Central nervous system Pharmacotherapy Neurogenesis Encephalon Psychosis Prenatal Adult Antagonist Human Drug Clozapine Injection Chronic D2 Dopamine receptor Treatment Working memory |
| Language | English |
| License | http://www.springer.com/tdm CC BY 4.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c541t-1653dcf9d6625ffbb185ae9f39a3968f44aae0512d65bacac5ec142ed5b2d70f3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 |
| OpenAccessLink | https://www.research-collection.ethz.ch/bitstream/20.500.11850/15960/2/213_2009_Article_1754.pdf |
| PMID | 20041229 |
| PQID | 218967797 |
| PQPubID | 47309 |
| PageCount | 13 |
| ParticipantIDs | proquest_miscellaneous_746048750 proquest_miscellaneous_734261938 proquest_journals_218967797 pubmed_primary_20041229 pascalfrancis_primary_22393388 crossref_citationtrail_10_1007_s00213_009_1754_6 crossref_primary_10_1007_s00213_009_1754_6 springer_journals_10_1007_s00213_009_1754_6 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2010-03-01 |
| PublicationDateYYYYMMDD | 2010-03-01 |
| PublicationDate_xml | – month: 03 year: 2010 text: 2010-03-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Berlin/Heidelberg |
| PublicationPlace_xml | – name: Berlin/Heidelberg – name: Berlin – name: Germany – name: Heidelberg |
| PublicationTitle | Psychopharmacologia |
| PublicationTitleAbbrev | Psychopharmacology |
| PublicationTitleAlternate | Psychopharmacology (Berl) |
| PublicationYear | 2010 |
| Publisher | Springer-Verlag Springer Springer Nature B.V |
| Publisher_xml | – name: Springer-Verlag – name: Springer – name: Springer Nature B.V |
| References | Fatemi (CR24) 2005 Grace, Bellus, Raulin, Herz, Priest, Brenner, Donnelly, Smith, Gunn (CR34) 1996; 47 Harrison (CR37) 1999; 122 Ozawa, Hashimoto, Kishimoto, Shimizu, Ishikura, Iyo (CR60) 2006; 59 Brown, Susser (CR12) 2002; 8 Kralic, Ledergerber, Fritschy (CR42) 2005; 22 Balu, Lucki (CR6) 2009; 33 Brown, Vinogradov, Kremen, Poole, Deicken, Penner, McKeague, Kochetkova, Kern, Schaefer (CR14) 2009; 166 Gilbert, Kesner, DeCoteau (CR30) 1998; 18 Meyer, Yee, Feldon (CR51) 2007; 13 Moser, Moser, Andersen (CR56) 1993; 13 Cui, Ashdown, Luheshi, Boksa (CR21) 2009; 113 Bessa, Ferreira, Melo, Marques, Cerqueira, Palha, Almeida, Sousa (CR8) 2009; 14 Lee, Kesner (CR43) 2003; 23 Patterson (CR63) 2009; 204 Clancy, Darlington, Finlay (CR16) 2001; 105 Brown (CR11) 2006; 32 Schmitt, Weber, Jatzko, Braus, Henn (CR69) 2004; 111 Addy, Pocivavsek, Levin (CR1) 2005; 30 Baddeley (CR5) 2003; 4 Delatour, Gisquet-Verrier (CR22) 1999; 113 Franklin, Paxinos (CR26) 2008 Lee, Jayathilake, Meltzer (CR44) 1999; 37 Meyer, Engler, Weber, Schedlowski, Feldon (CR52) 2008; 154 Halim, Weickert, McClintock, Weinberger, Lipska (CR36) 2004; 29 Meyer, Feldon, Fatemi (CR54) 2009; 33 Clancy, Kersh, Hyde, Darlington, Anand, Finlay (CR17) 2007; 5 Steele, Morris (CR73) 1999; 9 Gilmore, Jarskog (CR32) 1997; 24 Reif, Schmitt, Fritzen, Lesch (CR67) 2007; 257 Bessa, Ferreira, Melo, Marques, Cerqueira, Palha, Almeida, Sousa (CR9) 2009; 14 Kesner (CR41) 2007; 163 Shapiro, Olton, Schacter, Tulving (CR70) 1994 Shi, Fatemi, Sidwell, Patterson (CR72) 2003; 23 McGurk, Carter, Goldman, Green, Marder, Xie, Schooler, Kane (CR47) 2005; 162 Zuckerman, Weiner (CR78) 2005; 39 Couillard-Despres, Winner, Schaubeck, Aigner, Vroemen, Weidner, Bogdahn, Winkler, Kuhn, Aigner (CR19) 2005; 21 Fritschy, Weinmann, Wenzel, Benke (CR27) 1998; 390 Kempermann, Jessberger, Steiner, Kronenberg (CR39) 2004; 27 Antonova, Sharma, Morris, Kumari (CR4) 2004; 70 Dolbeare (CR23) 1995; 27 Olton, Papas (CR58) 1979; 17 Samuelsson, Jennische, Hansson, Holmäng (CR68) 2006; 290 Weinberger (CR77) 1999; 45 Galletly, Clark, McFarlane (CR29) 2005; 15 CR15 Meyer, Feldon, Schedlowski, Yee (CR49) 2005; 29 Hagger, Buckley, Kenny, Friedman, Ubogy, Meltzer (CR35) 1993; 34 Meyer, Feldon, Yee (CR55) 2009; 35 Rahimi, Claiborne (CR65) 2007; 163 Leutgeb, Leutgeb, Moser, Moser (CR45) 2007; 315 O'Donnell, Grace (CR57) 1998; 24 Maeda, Sugino, Hirose, Kitagawa, Nagai, Mizoguchi, Takuma, Yamada (CR46) 2007; 103 Sharma, Hughes, Soni, Kumari (CR71) 2003; 169 Pocivavsek, Icenogle, Levin (CR64) 2006; 188 Reif, Fritzen, Finger, Strobel, Lauer, Schmitt, Lesch (CR66) 2006; 11 Clelland, Choi, Romberg, Clemenson, Fragniere, Tyers, Jessberger, Saksida, Barker, Gage, Bussey (CR18) 2009; 325 Zuckerman, Rehavi, Nachman, Weiner (CR79) 2003; 28 Altman, Das (CR3) 1965; 207 Kempermann, Krebs, Fabel (CR40) 2008; 21 Broersen (CR10) 2000; 126 Coyle, Tran, Fung, Summers, Rofe (CR20) 2009; 197 Goodrich-Hunsaker, Hunsaker, Kesner (CR33) 2008; 122 Bannerman, Rawlins, McHugh, Deacon, Yee, Bast, Zhang, Pothuizen, Feldon (CR7) 2004; 28 Meyer, Nyffeler, Yee, Knuesel, Feldon (CR53) 2008; 22 van Praag, Schinder, Christie, Toni, Palmer, Gage (CR76) 2002; 415 Patterson (CR62) 2007; 318 Adler, Grieshaber, Faude, Thebaldi, Dressing (CR2) 2002; 35 Francis, Koulakoff, Boucher, Chafey, Schaar, Vinet, Friocourt, McDonnell, Reiner, Kahn, McConnell, Berwald-Netter, Denoulet, Chelly (CR25) 1999; 23 Meyer, Nyffeler, Engler, Urwyler, Schedlowski, Knuesel, Yee, Feldon (CR50) 2006; 26 Harrison (CR38) 2004; 174 Olton, Wible, Shapiro (CR59) 1986; 100 Brown, Couillard-Després, Cooper-Kuhn, Winkler, Aigner, Kuhn (CR13) 2003; 467 Patterson (CR61) 2002; 12 Galletly, Clark, McFarlane, Weber (CR28) 1997; 72 Gilbert, Kesner, Lee (CR31) 2001; 11 Toro, Deakin (CR75) 2007; 90 Meyer, Feldon (CR48) 2009; 204 Tamminga (CR74) 2006; 67 K Maeda (1754_CR46) 2007; 103 PJ Harrison (1754_CR37) 1999; 122 U Meyer (1754_CR52) 2008; 154 U Meyer (1754_CR51) 2007; 13 AS Brown (1754_CR14) 2009; 166 A Baddeley (1754_CR5) 2003; 4 L Zuckerman (1754_CR78) 2005; 39 E Moser (1754_CR56) 1993; 13 B Delatour (1754_CR22) 1999; 113 JE Kralic (1754_CR42) 2005; 22 RP Kesner (1754_CR41) 2007; 163 PH Patterson (1754_CR63) 2009; 204 T Sharma (1754_CR71) 2003; 169 B Clancy (1754_CR17) 2007; 5 JM Bessa (1754_CR8) 2009; 14 JP Brown (1754_CR13) 2003; 467 U Meyer (1754_CR49) 2005; 29 O Rahimi (1754_CR65) 2007; 163 JM Fritschy (1754_CR27) 1998; 390 P O'Donnell (1754_CR57) 1998; 24 DR Weinberger (1754_CR77) 1999; 45 J Altman (1754_CR3) 1965; 207 KBJ Franklin (1754_CR26) 2008 CA Galletly (1754_CR29) 2005; 15 G Kempermann (1754_CR39) 2004; 27 DM Bannerman (1754_CR7) 2004; 28 F Francis (1754_CR25) 1999; 23 B Clancy (1754_CR16) 2001; 105 A Reif (1754_CR66) 2006; 11 AS Brown (1754_CR12) 2002; 8 E Antonova (1754_CR4) 2004; 70 S Couillard-Despres (1754_CR19) 2005; 21 L Zuckerman (1754_CR79) 2003; 28 G Kempermann (1754_CR40) 2008; 21 PH Patterson (1754_CR62) 2007; 318 JM Bessa (1754_CR9) 2009; 14 1754_CR15 AM Samuelsson (1754_CR68) 2006; 290 DT Balu (1754_CR6) 2009; 33 NA Addy (1754_CR1) 2005; 30 SH Fatemi (1754_CR24) 2005 MA Lee (1754_CR44) 1999; 37 A Pocivavsek (1754_CR64) 2006; 188 P Coyle (1754_CR20) 2009; 197 NJ Goodrich-Hunsaker (1754_CR33) 2008; 122 ML Shapiro (1754_CR70) 1994 U Meyer (1754_CR54) 2009; 33 G Adler (1754_CR2) 2002; 35 U Meyer (1754_CR53) 2008; 22 PE Gilbert (1754_CR31) 2001; 11 RJ Steele (1754_CR73) 1999; 9 H Praag van (1754_CR76) 2002; 415 U Meyer (1754_CR50) 2006; 26 I Lee (1754_CR43) 2003; 23 L Shi (1754_CR72) 2003; 23 CT Toro (1754_CR75) 2007; 90 DS Olton (1754_CR58) 1979; 17 LM Broersen (1754_CR10) 2000; 126 K Cui (1754_CR21) 2009; 113 AS Brown (1754_CR11) 2006; 32 A Schmitt (1754_CR69) 2004; 111 U Meyer (1754_CR55) 2009; 35 PJ Harrison (1754_CR38) 2004; 174 DS Olton (1754_CR59) 1986; 100 CD Clelland (1754_CR18) 2009; 325 A Reif (1754_CR67) 2007; 257 PH Patterson (1754_CR61) 2002; 12 F Dolbeare (1754_CR23) 1995; 27 J Grace (1754_CR34) 1996; 47 C Hagger (1754_CR35) 1993; 34 ND Halim (1754_CR36) 2004; 29 SR McGurk (1754_CR47) 2005; 162 PE Gilbert (1754_CR30) 1998; 18 CA Galletly (1754_CR28) 1997; 72 JH Gilmore (1754_CR32) 1997; 24 JK Leutgeb (1754_CR45) 2007; 315 K Ozawa (1754_CR60) 2006; 59 U Meyer (1754_CR48) 2009; 204 CA Tamminga (1754_CR74) 2006; 67 16415915 - Mol Psychiatry. 2006 May;11(5):514-22 17468935 - Eur Arch Psychiatry Clin Neurosci. 2007 Aug;257(5):290-9 16262631 - Eur J Neurosci. 2005 Oct;22(8):1916-27 17426354 - Neuroinformatics. 2007 Spring;5(1):79-94 8366351 - J Neurosci. 1993 Sep;13(9):3916-25 19442688 - Neurosci Biobehav Rev. 2009 Jul;33(7):1061-79 17765718 - Prog Brain Res. 2007;163:167-81 11861174 - Curr Opin Neurobiol. 2002 Feb;12(1):115-8 17341843 - J Pharmacol Sci. 2007 Mar;103(3):299-308 15654838 - Eur J Neurosci. 2005 Jan;21(1):1-14 19369317 - Am J Psychiatry. 2009 Jun;166(6):683-90 18793679 - Behav Brain Res. 2009 Jan 30;197(1):210-8 11483296 - Neuroscience. 2001;105(1):7-17 11875571 - Nature. 2002 Feb 28;415(6875):1030-4 14574675 - J Comp Neurol. 2003 Dec 1;467(1):1-10 9134598 - Schizophr Res. 1997 Apr 11;24(3):365-7 11921387 - Ment Retard Dev Disabil Res Rev. 2002;8(1):51-7 10226773 - Hippocampus. 1999;9(2):118-36 10219775 - Brain. 1999 Apr;122 ( Pt 4):593-624 10399932 - Neuron. 1999 Jun;23(2):247-56 18382230 - Curr Opin Psychiatry. 2008 May;21(3):290-5 11811656 - Hippocampus. 2001;11(6):626-36 11105641 - Prog Brain Res. 2000;126:79-94 12865897 - Neuropsychopharmacology. 2003 Oct;28(10):1778-89 3545260 - Behav Neurosci. 1986 Dec;100(6):852-5 18982002 - Mol Psychiatry. 2009 Aug;14 (8):764-73, 739 16469941 - Schizophr Bull. 2006 Apr;32(2):200-2 16256957 - Biol Psychiatry. 2006 Mar 15;59(6):546-54 8925344 - Psychiatr Serv. 1996 Jan;47(1):41-5 10571477 - Behav Neurosci. 1999 Oct;113(5):941-55 18023140 - Brain Behav Immun. 2008 May;22(4):469-86 16965183 - J Clin Psychiatry. 2006;67 Suppl 9:9-13; discussion 36-42 15905072 - Eur Neuropsychopharmacol. 2005 Dec;15(6):601-8 12237790 - Pharmacopsychiatry. 2002 Sep;35(5):190-4 15688087 - Neuropsychopharmacology. 2005 Jun;30(6):1121-7 19590004 - Science. 2009 Jul 10;325(5937):210-3 10227103 - Schizophr Res. 1999 May 4;37(1):1-11 16715255 - Psychopharmacology (Berl). 2006 Nov;188(4):597-604 18408229 - Schizophr Bull. 2009 Sep;35(5):959-72 15225971 - Neurosci Biobehav Rev. 2004 May;28(3):273-83 17303747 - Science. 2007 Feb 16;315(5814):961-6 14523382 - Nat Rev Neurosci. 2003 Oct;4(10):829-39 12845415 - Psychopharmacology (Berl). 2003 Sep;169(3-4):398-403 15010699 - Neuropsychopharmacology. 2004 Jun;29(6):1063-9 14714218 - J Neural Transm (Vienna). 2004 Jan;111(1):91-100 16672647 - J Neurosci. 2006 May 3;26(18):4752-62 18298245 - Behav Neurosci. 2008 Feb;122(1):16-26 12598640 - J Neurosci. 2003 Feb 15;23(4):1517-23 9613625 - Schizophr Bull. 1998;24(2):267-83 19136031 - Behav Brain Res. 2009 Dec 7;204(2):313-21 15271491 - Trends Neurosci. 2004 Aug;27(8):447-52 17519367 - Neuroscientist. 2007 Jun;13(3):241-56 19464151 - Schizophr Res. 2009 Sep;113(2-3):288-97 19154759 - Behav Brain Res. 2009 Dec 7;204(2):322-34 15329292 - Schizophr Res. 2004 Oct 1;70(2-3):117-45 9453664 - J Comp Neurol. 1998 Jan 12;390(2):194-210 16357100 - Am J Physiol Regul Integr Comp Physiol. 2006 May;290(5):R1345-56 19636313 - Mol Psychiatry. 2010 Apr;15(4):415-25 12514227 - J Neurosci. 2003 Jan 1;23(1):297-302 17962542 - Science. 2007 Oct 26;318(5850):576-7 10071707 - Biol Psychiatry. 1999 Feb 15;45(4):395-402 17123784 - Schizophr Res. 2007 Feb;90(1-3):1-14 15725430 - J Psychiatr Res. 2005 May;39(3):311-23 7657555 - Histochem J. 1995 May;27(5):339-69 15205886 - Psychopharmacology (Berl). 2004 Jun;174(1):151-62 522981 - Neuropsychologia. 1979;17(6):669-82 9425021 - J Neurosci. 1998 Jan 15;18(2):804-10 18495356 - Neuroscience. 2008 Jun 23;154(2):701-9 8292674 - Biol Psychiatry. 1993 Nov 15;34(10):702-12 17765738 - Prog Brain Res. 2007;163:567-76 15863811 - Am J Psychiatry. 2005 May;162(5):1013-6 18786562 - Neurosci Biobehav Rev. 2009 Mar;33(3):232-52 5886931 - Nature. 1965 Aug 28;207(5000):953-6 9406905 - Psychiatry Res. 1997 Oct 10;72(3):161-6 15964075 - Neurosci Biobehav Rev. 2005;29(6):913-47 |
| References_xml | – volume: 45 start-page: 95 year: 1999 end-page: 402 ident: CR77 article-title: Cell biology of the hippocampal formation in schizophrenia publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(98)00331-X – volume: 113 start-page: 941 year: 1999 end-page: 955 ident: CR22 article-title: Lesions of the prelimbic–infralimbic cortices in rats do not disrupt response selection processes but induce delay-dependent deficits: evidence for a role in working memory? publication-title: Behav Neurosci doi: 10.1037/0735-7044.113.5.941 – volume: 113 start-page: 288 year: 2009 end-page: 297 ident: CR21 article-title: Effects of prenatal immune activation on hippocampal neurogenesis in the rat publication-title: Schizophr Res doi: 10.1016/j.schres.2009.05.003 – volume: 32 start-page: 200 year: 2006 end-page: 202 ident: CR11 article-title: Prenatal infection as a risk factor for schizophrenia publication-title: Schizophr Bull doi: 10.1093/schbul/sbj052 – volume: 467 start-page: 1 year: 2003 end-page: 10 ident: CR13 article-title: Transient expression of doublecortin during adult neurogenesis publication-title: J Comp Neurol doi: 10.1002/cne.10874 – volume: 174 start-page: 151 year: 2004 end-page: 162 ident: CR38 article-title: The hippocampus in schizophrenia: a review of the neuropathological evidence and its pathophysiological implications publication-title: Psychopharmacology doi: 10.1007/s00213-003-1761-y – volume: 27 start-page: 447 year: 2004 end-page: 452 ident: CR39 article-title: Milestones of neuronal development in the adult hippocampus publication-title: Trends Neurosci doi: 10.1016/j.tins.2004.05.013 – volume: 26 start-page: 4752 year: 2006 end-page: 4762 ident: CR50 article-title: The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology publication-title: J Neurosci doi: 10.1523/JNEUROSCI.0099-06.2006 – volume: 23 start-page: 297 year: 2003 end-page: 302 ident: CR72 article-title: Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring publication-title: J Neurosci – volume: 204 start-page: 322 year: 2009 end-page: 334 ident: CR48 article-title: Neural basis of psychosis-related behaviour in the infection model of schizophrenia publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.12.022 – volume: 11 start-page: 626 year: 2001 end-page: 636 ident: CR31 article-title: Dissociating hippocampal subregions: double dissociation between dentate gyrus and CA1 publication-title: Hippocampus doi: 10.1002/hipo.1077 – volume: 122 start-page: 16 year: 2008 end-page: 26 ident: CR33 article-title: The interactions and dissociations of the dorsal hippocampus subregions: how the dentate gyrus, CA3, and CA1 process spatial information publication-title: Behav Neurosci doi: 10.1037/0735-7044.122.1.16 – volume: 23 start-page: 247 year: 1999 end-page: 256 ident: CR25 article-title: Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons publication-title: Neuron doi: 10.1016/S0896-6273(00)80777-1 – volume: 59 start-page: 546 year: 2006 end-page: 554 ident: CR60 article-title: Immune activation during pregnancy in mice leads to dopaminergic hyperfunction and cognitive impairment in the offspring: a neurodevelopmental animal model of schizophrenia publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2005.07.031 – volume: 105 start-page: 7 year: 2001 end-page: 17 ident: CR16 article-title: Translating developmental time across mammalian species publication-title: Neuroscience doi: 10.1016/S0306-4522(01)00171-3 – volume: 13 start-page: 241 year: 2007 end-page: 256 ident: CR51 article-title: The neurodevelopmental impact of prenatal infections at different times of pregnancy: the earlier the worse? publication-title: Neuroscientist doi: 10.1177/1073858406296401 – volume: 47 start-page: 41 year: 1996 end-page: 45 ident: CR34 article-title: Long-term impact of clozapine and psychosocial treatment on psychiatric symptoms and cognitive functioning publication-title: Psychiatr Serv – volume: 90 start-page: 1 year: 2007 end-page: 14 ident: CR75 article-title: Adult neurogenesis and schizophrenia: a window on abnormal early brain development? publication-title: Schizophr Res doi: 10.1016/j.schres.2006.09.030 – volume: 39 start-page: 311 year: 2005 end-page: 323 ident: CR78 article-title: Maternal immune activation leads to behavioral and pharmacological changes in the adult offspring publication-title: J Psychiatr Res doi: 10.1016/j.jpsychires.2004.08.008 – volume: 15 start-page: 601 year: 2005 end-page: 608 ident: CR29 article-title: Clozapine improves working memory updating in schizophrenia publication-title: Eur Neuropsychopharmacol doi: 10.1016/j.euroneuro.2005.03.001 – volume: 22 start-page: 1916 year: 2005 end-page: 1927 ident: CR42 article-title: Disruption of the neurogenic potential of the dentate gyrus in a mouse model of temporal lobe epilepsy with focal seizures publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2005.04386.x – volume: 315 start-page: 961 year: 2007 end-page: 966 ident: CR45 article-title: Pattern separation in the dentate gyrus and CA3 of the hippocampus publication-title: Science doi: 10.1126/science.1135801 – volume: 103 start-page: 299 year: 2007 end-page: 308 ident: CR46 article-title: Clozapine prevents a decrease in neurogenesis in mice repeatedly treated with phencyclidine publication-title: J Pharmacol Sci doi: 10.1254/jphs.FP0061424 – volume: 67 start-page: 9 issue: Suppl 9 year: 2006 end-page: 13 ident: CR74 article-title: The neurobiology of cognition in schizophrenia publication-title: J Clin Psychiatry – year: 2008 ident: CR26 publication-title: The mouse brain in stereotaxic coordinates – volume: 70 start-page: 117 year: 2004 end-page: 145 ident: CR4 article-title: The relationship between brain structure and neurocognition in schizophrenia: a selective review publication-title: Schizophr Res doi: 10.1016/j.schres.2003.12.002 – volume: 325 start-page: 210 year: 2009 end-page: 213 ident: CR18 article-title: A functional role for adult hippocampal neurogenesis in spatial pattern separation publication-title: Science doi: 10.1126/science.1173215 – volume: 21 start-page: 1 year: 2005 end-page: 14 ident: CR19 article-title: Doublecortin expression levels in adult brain reflect neurogenesis publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2004.03813.x – volume: 35 start-page: 959 year: 2009 end-page: 972 ident: CR55 article-title: A review of the fetal brain cytokine imbalance hypothesis of schizophrenia publication-title: Schizophr Bull doi: 10.1093/schbul/sbn022 – volume: 35 start-page: 190 year: 2002 end-page: 194 ident: CR2 article-title: Clozapine in patients with chronic schizophrenia: serum level, EEG and memory performance publication-title: Pharmacopsychiatry doi: 10.1055/s-2002-34120 – volume: 28 start-page: 273 year: 2004 end-page: 283 ident: CR7 article-title: Regional dissociations within the hippocampus-memory and anxiety publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2004.03.004 – ident: CR15 – start-page: 141 year: 1994 end-page: 146 ident: CR70 article-title: Hippocampal function and interference publication-title: Memory systems – volume: 415 start-page: 1030 year: 2002 end-page: 1034 ident: CR76 article-title: Functional neurogenesis in the adult hippocampus publication-title: Nature doi: 10.1038/4151030a – volume: 163 start-page: 167 year: 2007 end-page: 181 ident: CR65 article-title: Morphological development and maturation of granule neuron dendrites in the rat dentate gyrus publication-title: Prog Brain Res doi: 10.1016/S0079-6123(07)63010-6 – volume: 18 start-page: 804 year: 1998 end-page: 810 ident: CR30 article-title: Memory for spatial location: role of the hippocampus in mediating spatial pattern separation publication-title: J Neurosci – volume: 11 start-page: 514 year: 2006 end-page: 522 ident: CR66 article-title: Neural stem cell proliferation is decreased in schizophrenia, but not in depression publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001791 – volume: 24 start-page: 365 year: 1997 end-page: 367 ident: CR32 article-title: Exposure to infection and brain development: cytokines in the pathogenesis of schizophrenia publication-title: Schizophr Res doi: 10.1016/S0920-9964(96)00123-5 – volume: 13 start-page: 3916 year: 1993 end-page: 3925 ident: CR56 article-title: Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions publication-title: J Neurosci – volume: 9 start-page: 118 year: 1999 end-page: 136 ident: CR73 article-title: Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5 publication-title: Hippocampus doi: 10.1002/(SICI)1098-1063(1999)9:2<118::AID-HIPO4>3.0.CO;2-8 – volume: 30 start-page: 1121 year: 2005 end-page: 1127 ident: CR1 article-title: Reversal of clozapine effects on working memory in rats with fimbria-fornix lesions publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300669 – volume: 204 start-page: 313 year: 2009 end-page: 321 ident: CR63 article-title: Immune involvement in schizophrenia and autism: etiology, pathology and animal models publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.12.016 – volume: 318 start-page: 576 year: 2007 end-page: 577 ident: CR62 article-title: Maternal effects on schizophrenia risk publication-title: Science doi: 10.1126/science.1150196 – volume: 290 start-page: R1345 year: 2006 end-page: R1356 ident: CR68 article-title: Prenatal exposure to interleukin-6 results in inflammatory neurodegeneration in hippocampus with NMDA/GABA(A) dysregulation and impaired spatial learning publication-title: Am J Physiol Regul Integr Comp Physiol – year: 2005 ident: CR24 publication-title: Neuropsychiatric disorders and infection – volume: 100 start-page: 852 year: 1986 end-page: 855 ident: CR59 article-title: Mnemonic theories of hippocampal function publication-title: Behav Neurosci doi: 10.1037/0735-7044.100.6.852 – volume: 33 start-page: 232 year: 2009 end-page: 252 ident: CR6 article-title: Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2008.08.007 – volume: 21 start-page: 290 year: 2008 end-page: 295 ident: CR40 article-title: The contribution of failing adult hippocampal neurogenesis to psychiatric disorders publication-title: Curr Opin Psychiatry doi: 10.1097/YCO.0b013e3282fad375 – volume: 29 start-page: 913 year: 2005 end-page: 947 ident: CR49 article-title: Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2004.10.012 – volume: 188 start-page: 597 year: 2006 end-page: 604 ident: CR64 article-title: Ventral hippocampal alpha7 and alpha4beta2 nicotinic receptor blockade and clozapine effects on memory in female rats publication-title: Psychopharmacology doi: 10.1007/s00213-006-0416-1 – volume: 28 start-page: 1778 year: 2003 end-page: 1789 ident: CR79 article-title: Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300248 – volume: 14 start-page: 739 year: 2009 ident: CR9 article-title: Hippocampal neurogenesis induced by antidepressant drugs: an epiphenomenon in their mood-improving actions publication-title: Mol Psychiatry doi: 10.1038/mp.2009.75 – volume: 12 start-page: 115 year: 2002 end-page: 118 ident: CR61 article-title: Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness publication-title: Curr Opin Neurobiol doi: 10.1016/S0959-4388(02)00299-4 – volume: 126 start-page: 79 year: 2000 end-page: 94 ident: CR10 article-title: Attentional processes and learning and memory in rats: the prefrontal cortex and hippocampus compared publication-title: Prog Brain Res doi: 10.1016/S0079-6123(00)26008-1 – volume: 5 start-page: 79 year: 2007 end-page: 94 ident: CR17 article-title: Web-based method for translating neurodevelopment from laboratory species to humans publication-title: Neuroinformatics – volume: 17 start-page: 669 year: 1979 end-page: 682 ident: CR58 article-title: Spatial memory and hippocampal function publication-title: Neuropsychologia doi: 10.1016/0028-3932(79)90042-3 – volume: 14 start-page: 764 year: 2009 end-page: 773 ident: CR8 article-title: The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling publication-title: Mol Psychiatry doi: 10.1038/mp.2008.119 – volume: 27 start-page: 339 year: 1995 end-page: 369 ident: CR23 article-title: Bromodeoxyuridine: a diagnostic tool in biology and medicine, part I: historical perspectives, histochemical methods and cell kinetics publication-title: Histochem J – volume: 257 start-page: 290 year: 2007 end-page: 299 ident: CR67 article-title: Neurogenesis and schizophrenia: dividing neurons in a divided mind? publication-title: Eur Arch Psychiatry Clin Neurosci doi: 10.1007/s00406-007-0733-3 – volume: 4 start-page: 829 year: 2003 end-page: 839 ident: CR5 article-title: Working memory: looking back and looking forward publication-title: Nat Rev Neurosci doi: 10.1038/nrn1201 – volume: 34 start-page: 702 year: 1993 end-page: 712 ident: CR35 article-title: Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine publication-title: Biol Psychiatry doi: 10.1016/0006-3223(93)90043-D – volume: 163 start-page: 567 year: 2007 end-page: 576 ident: CR41 article-title: A behavioral analysis of dentate gyrus function publication-title: Prog Brain Res doi: 10.1016/S0079-6123(07)63030-1 – volume: 390 start-page: 194 year: 1998 end-page: 210 ident: CR27 article-title: Synapse-specific localization of NMDA and GABA(A) receptor subunits revealed by antigen-retrieval immunohistochemistry publication-title: J Comp Neurol doi: 10.1002/(SICI)1096-9861(19980112)390:2<194::AID-CNE3>3.0.CO;2-X – volume: 166 start-page: 683 year: 2009 end-page: 690 ident: CR14 article-title: Prenatal exposure to maternal infection and executive dysfunction in adult schizophrenia publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.2008.08010089 – volume: 22 start-page: 469 year: 2008 end-page: 486 ident: CR53 article-title: Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2007.09.012 – volume: 23 start-page: 1517 year: 2003 end-page: 1523 ident: CR43 article-title: Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory publication-title: J Neurosci – volume: 169 start-page: 398 year: 2003 end-page: 403 ident: CR71 article-title: Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia publication-title: Psychopharmacology doi: 10.1007/s00213-003-1506-y – volume: 29 start-page: 1063 year: 2004 end-page: 1069 ident: CR36 article-title: Effects of chronic haloperidol and clozapine treatment on neurogenesis in the adult rat hippocampus publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300422 – volume: 37 start-page: 1 year: 1999 end-page: 11 ident: CR44 article-title: A comparison of the effect of clozapine with typical neuroleptics on cognitive function in neuroleptic–responsive schizophrenia publication-title: Schizophr Res doi: 10.1016/S0920-9964(98)00145-5 – volume: 197 start-page: 210 year: 2009 end-page: 218 ident: CR20 article-title: Maternal dietary zinc supplementation prevents aberrant behaviour in an object recognition task in mice offspring exposed to LPS in early pregnancy publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.08.022 – volume: 207 start-page: 953 year: 1965 end-page: 956 ident: CR3 article-title: Post-natal origin of microneurones in the rat brain publication-title: Nature doi: 10.1038/207953a0 – volume: 8 start-page: 51 year: 2002 end-page: 57 ident: CR12 article-title: In utero infection and adult schizophrenia publication-title: Ment Retard Dev Disabil Res Rev doi: 10.1002/mrdd.10004 – volume: 72 start-page: 161 year: 1997 end-page: 166 ident: CR28 article-title: Relationships between changes in symptoms ratings, neuropsychological test performance, and quality of life in schizophrenic patients with clozapine publication-title: Psychiatry Res doi: 10.1016/S0165-1781(97)00062-0 – volume: 33 start-page: 1061 year: 2009 end-page: 1079 ident: CR54 article-title: In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2009.05.001 – volume: 24 start-page: 267 year: 1998 end-page: 283 ident: CR57 article-title: Dysfunctions in multiple interrelated systems as the neurobiological bases of schizophrenic symptom clusters publication-title: Schizophr Bull – volume: 122 start-page: 593 year: 1999 end-page: 624 ident: CR37 article-title: The neuropathology of schizophrenia. A critical review of the data and their interpretation publication-title: Brain doi: 10.1093/brain/122.4.593 – volume: 111 start-page: 91 year: 2004 end-page: 100 ident: CR69 article-title: Hippocampal volume and cell proliferation after acute and chronic clozapine or haloperidol treatment publication-title: J Neural Transm doi: 10.1007/s00702-003-0070-2 – volume: 154 start-page: 701 year: 2008 end-page: 709 ident: CR52 article-title: Preliminary evidence for a modulation of fetal dopaminergic development by maternal immune activation during pregnancy publication-title: Neuroscience doi: 10.1016/j.neuroscience.2008.04.031 – volume: 162 start-page: 1013 year: 2005 end-page: 1036 ident: CR47 article-title: The effects of clozapine and risperidone on spatial working memory in schizophrenia publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.162.5.1013 – ident: 1754_CR15 doi: 10.1038/mp.2009.66 – volume: 11 start-page: 626 year: 2001 ident: 1754_CR31 publication-title: Hippocampus doi: 10.1002/hipo.1077 – volume: 318 start-page: 576 year: 2007 ident: 1754_CR62 publication-title: Science doi: 10.1126/science.1150196 – volume: 26 start-page: 4752 year: 2006 ident: 1754_CR50 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.0099-06.2006 – volume: 122 start-page: 16 year: 2008 ident: 1754_CR33 publication-title: Behav Neurosci doi: 10.1037/0735-7044.122.1.16 – volume: 103 start-page: 299 year: 2007 ident: 1754_CR46 publication-title: J Pharmacol Sci doi: 10.1254/jphs.FP0061424 – volume: 28 start-page: 1778 year: 2003 ident: 1754_CR79 publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300248 – volume: 24 start-page: 365 year: 1997 ident: 1754_CR32 publication-title: Schizophr Res doi: 10.1016/S0920-9964(96)00123-5 – volume: 33 start-page: 1061 year: 2009 ident: 1754_CR54 publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2009.05.001 – volume: 30 start-page: 1121 year: 2005 ident: 1754_CR1 publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300669 – volume: 12 start-page: 115 year: 2002 ident: 1754_CR61 publication-title: Curr Opin Neurobiol doi: 10.1016/S0959-4388(02)00299-4 – volume: 257 start-page: 290 year: 2007 ident: 1754_CR67 publication-title: Eur Arch Psychiatry Clin Neurosci doi: 10.1007/s00406-007-0733-3 – volume: 290 start-page: R1345 year: 2006 ident: 1754_CR68 publication-title: Am J Physiol Regul Integr Comp Physiol doi: 10.1152/ajpregu.00268.2005 – volume: 13 start-page: 3916 year: 1993 ident: 1754_CR56 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.13-09-03916.1993 – volume: 15 start-page: 601 year: 2005 ident: 1754_CR29 publication-title: Eur Neuropsychopharmacol doi: 10.1016/j.euroneuro.2005.03.001 – volume: 14 start-page: 739 year: 2009 ident: 1754_CR9 publication-title: Mol Psychiatry doi: 10.1038/mp.2009.75 – volume: 29 start-page: 1063 year: 2004 ident: 1754_CR36 publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300422 – volume: 100 start-page: 852 year: 1986 ident: 1754_CR59 publication-title: Behav Neurosci doi: 10.1037/0735-7044.100.6.852 – volume: 197 start-page: 210 year: 2009 ident: 1754_CR20 publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.08.022 – volume: 59 start-page: 546 year: 2006 ident: 1754_CR60 publication-title: Biol Psychiatry doi: 10.1016/j.biopsych.2005.07.031 – volume: 28 start-page: 273 year: 2004 ident: 1754_CR7 publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2004.03.004 – volume: 154 start-page: 701 year: 2008 ident: 1754_CR52 publication-title: Neuroscience doi: 10.1016/j.neuroscience.2008.04.031 – volume-title: The mouse brain in stereotaxic coordinates year: 2008 ident: 1754_CR26 – volume: 5 start-page: 79 year: 2007 ident: 1754_CR17 publication-title: Neuroinformatics doi: 10.1385/NI:5:1:79 – volume: 113 start-page: 941 year: 1999 ident: 1754_CR22 publication-title: Behav Neurosci doi: 10.1037/0735-7044.113.5.941 – volume: 14 start-page: 764 year: 2009 ident: 1754_CR8 publication-title: Mol Psychiatry doi: 10.1038/mp.2008.119 – volume: 67 start-page: 9 issue: Suppl 9 year: 2006 ident: 1754_CR74 publication-title: J Clin Psychiatry – volume: 72 start-page: 161 year: 1997 ident: 1754_CR28 publication-title: Psychiatry Res doi: 10.1016/S0165-1781(97)00062-0 – volume: 415 start-page: 1030 year: 2002 ident: 1754_CR76 publication-title: Nature doi: 10.1038/4151030a – volume: 8 start-page: 51 year: 2002 ident: 1754_CR12 publication-title: Ment Retard Dev Disabil Res Rev doi: 10.1002/mrdd.10004 – volume: 174 start-page: 151 year: 2004 ident: 1754_CR38 publication-title: Psychopharmacology doi: 10.1007/s00213-003-1761-y – volume: 29 start-page: 913 year: 2005 ident: 1754_CR49 publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2004.10.012 – volume: 188 start-page: 597 year: 2006 ident: 1754_CR64 publication-title: Psychopharmacology doi: 10.1007/s00213-006-0416-1 – volume: 37 start-page: 1 year: 1999 ident: 1754_CR44 publication-title: Schizophr Res doi: 10.1016/S0920-9964(98)00145-5 – volume: 18 start-page: 804 year: 1998 ident: 1754_CR30 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.18-02-00804.1998 – volume: 17 start-page: 669 year: 1979 ident: 1754_CR58 publication-title: Neuropsychologia doi: 10.1016/0028-3932(79)90042-3 – volume: 32 start-page: 200 year: 2006 ident: 1754_CR11 publication-title: Schizophr Bull doi: 10.1093/schbul/sbj052 – volume: 21 start-page: 1 year: 2005 ident: 1754_CR19 publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2004.03813.x – volume: 27 start-page: 339 year: 1995 ident: 1754_CR23 publication-title: Histochem J doi: 10.1007/BF02389022 – volume: 105 start-page: 7 year: 2001 ident: 1754_CR16 publication-title: Neuroscience doi: 10.1016/S0306-4522(01)00171-3 – volume: 113 start-page: 288 year: 2009 ident: 1754_CR21 publication-title: Schizophr Res doi: 10.1016/j.schres.2009.05.003 – volume: 163 start-page: 167 year: 2007 ident: 1754_CR65 publication-title: Prog Brain Res doi: 10.1016/S0079-6123(07)63010-6 – volume: 207 start-page: 953 year: 1965 ident: 1754_CR3 publication-title: Nature doi: 10.1038/207953a0 – volume: 162 start-page: 1013 year: 2005 ident: 1754_CR47 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.162.5.1013 – volume: 27 start-page: 447 year: 2004 ident: 1754_CR39 publication-title: Trends Neurosci doi: 10.1016/j.tins.2004.05.013 – volume: 35 start-page: 190 year: 2002 ident: 1754_CR2 publication-title: Pharmacopsychiatry doi: 10.1055/s-2002-34120 – volume: 47 start-page: 41 year: 1996 ident: 1754_CR34 publication-title: Psychiatr Serv doi: 10.1176/ps.47.1.41 – volume: 23 start-page: 297 year: 2003 ident: 1754_CR72 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-01-00297.2003 – start-page: 141 volume-title: Memory systems year: 1994 ident: 1754_CR70 – volume: 90 start-page: 1 year: 2007 ident: 1754_CR75 publication-title: Schizophr Res doi: 10.1016/j.schres.2006.09.030 – volume: 315 start-page: 961 year: 2007 ident: 1754_CR45 publication-title: Science doi: 10.1126/science.1135801 – volume: 70 start-page: 117 year: 2004 ident: 1754_CR4 publication-title: Schizophr Res doi: 10.1016/j.schres.2003.12.002 – volume: 111 start-page: 91 year: 2004 ident: 1754_CR69 publication-title: J Neural Transm doi: 10.1007/s00702-003-0070-2 – volume: 169 start-page: 398 year: 2003 ident: 1754_CR71 publication-title: Psychopharmacology doi: 10.1007/s00213-003-1506-y – volume: 13 start-page: 241 year: 2007 ident: 1754_CR51 publication-title: Neuroscientist doi: 10.1177/1073858406296401 – volume: 22 start-page: 469 year: 2008 ident: 1754_CR53 publication-title: Brain Behav Immun doi: 10.1016/j.bbi.2007.09.012 – volume: 166 start-page: 683 year: 2009 ident: 1754_CR14 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.2008.08010089 – volume: 11 start-page: 514 year: 2006 ident: 1754_CR66 publication-title: Mol Psychiatry doi: 10.1038/sj.mp.4001791 – volume: 9 start-page: 118 year: 1999 ident: 1754_CR73 publication-title: Hippocampus doi: 10.1002/(SICI)1098-1063(1999)9:2<118::AID-HIPO4>3.0.CO;2-8 – volume: 34 start-page: 702 year: 1993 ident: 1754_CR35 publication-title: Biol Psychiatry doi: 10.1016/0006-3223(93)90043-D – volume: 21 start-page: 290 year: 2008 ident: 1754_CR40 publication-title: Curr Opin Psychiatry doi: 10.1097/YCO.0b013e3282fad375 – volume: 35 start-page: 959 year: 2009 ident: 1754_CR55 publication-title: Schizophr Bull doi: 10.1093/schbul/sbn022 – volume: 39 start-page: 311 year: 2005 ident: 1754_CR78 publication-title: J Psychiatr Res doi: 10.1016/j.jpsychires.2004.08.008 – volume: 22 start-page: 1916 year: 2005 ident: 1754_CR42 publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2005.04386.x – volume: 325 start-page: 210 year: 2009 ident: 1754_CR18 publication-title: Science doi: 10.1126/science.1173215 – volume: 122 start-page: 593 year: 1999 ident: 1754_CR37 publication-title: Brain doi: 10.1093/brain/122.4.593 – volume: 390 start-page: 194 year: 1998 ident: 1754_CR27 publication-title: J Comp Neurol doi: 10.1002/(SICI)1096-9861(19980112)390:2<194::AID-CNE3>3.0.CO;2-X – volume: 204 start-page: 322 year: 2009 ident: 1754_CR48 publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.12.022 – volume: 467 start-page: 1 year: 2003 ident: 1754_CR13 publication-title: J Comp Neurol doi: 10.1002/cne.10874 – volume: 33 start-page: 232 year: 2009 ident: 1754_CR6 publication-title: Neurosci Biobehav Rev doi: 10.1016/j.neubiorev.2008.08.007 – volume: 163 start-page: 567 year: 2007 ident: 1754_CR41 publication-title: Prog Brain Res doi: 10.1016/S0079-6123(07)63030-1 – volume: 24 start-page: 267 year: 1998 ident: 1754_CR57 publication-title: Schizophr Bull doi: 10.1093/oxfordjournals.schbul.a033325 – volume: 204 start-page: 313 year: 2009 ident: 1754_CR63 publication-title: Behav Brain Res doi: 10.1016/j.bbr.2008.12.016 – volume-title: Neuropsychiatric disorders and infection year: 2005 ident: 1754_CR24 doi: 10.3109/9780203007648 – volume: 4 start-page: 829 year: 2003 ident: 1754_CR5 publication-title: Nat Rev Neurosci doi: 10.1038/nrn1201 – volume: 23 start-page: 247 year: 1999 ident: 1754_CR25 publication-title: Neuron doi: 10.1016/S0896-6273(00)80777-1 – volume: 126 start-page: 79 year: 2000 ident: 1754_CR10 publication-title: Prog Brain Res doi: 10.1016/S0079-6123(00)26008-1 – volume: 23 start-page: 1517 year: 2003 ident: 1754_CR43 publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-04-01517.2003 – volume: 45 start-page: 95 year: 1999 ident: 1754_CR77 publication-title: Biol Psychiatry doi: 10.1016/S0006-3223(98)00331-X – reference: 16715255 - Psychopharmacology (Berl). 2006 Nov;188(4):597-604 – reference: 9613625 - Schizophr Bull. 1998;24(2):267-83 – reference: 17468935 - Eur Arch Psychiatry Clin Neurosci. 2007 Aug;257(5):290-9 – reference: 19464151 - Schizophr Res. 2009 Sep;113(2-3):288-97 – reference: 3545260 - Behav Neurosci. 1986 Dec;100(6):852-5 – reference: 11811656 - Hippocampus. 2001;11(6):626-36 – reference: 10571477 - Behav Neurosci. 1999 Oct;113(5):941-55 – reference: 9425021 - J Neurosci. 1998 Jan 15;18(2):804-10 – reference: 15863811 - Am J Psychiatry. 2005 May;162(5):1013-6 – reference: 16965183 - J Clin Psychiatry. 2006;67 Suppl 9:9-13; discussion 36-42 – reference: 19154759 - Behav Brain Res. 2009 Dec 7;204(2):322-34 – reference: 15654838 - Eur J Neurosci. 2005 Jan;21(1):1-14 – reference: 19636313 - Mol Psychiatry. 2010 Apr;15(4):415-25 – reference: 18786562 - Neurosci Biobehav Rev. 2009 Mar;33(3):232-52 – reference: 15329292 - Schizophr Res. 2004 Oct 1;70(2-3):117-45 – reference: 15964075 - Neurosci Biobehav Rev. 2005;29(6):913-47 – reference: 11105641 - Prog Brain Res. 2000;126:79-94 – reference: 9453664 - J Comp Neurol. 1998 Jan 12;390(2):194-210 – reference: 18408229 - Schizophr Bull. 2009 Sep;35(5):959-72 – reference: 12514227 - J Neurosci. 2003 Jan 1;23(1):297-302 – reference: 15010699 - Neuropsychopharmacology. 2004 Jun;29(6):1063-9 – reference: 18298245 - Behav Neurosci. 2008 Feb;122(1):16-26 – reference: 15688087 - Neuropsychopharmacology. 2005 Jun;30(6):1121-7 – reference: 12865897 - Neuropsychopharmacology. 2003 Oct;28(10):1778-89 – reference: 15905072 - Eur Neuropsychopharmacol. 2005 Dec;15(6):601-8 – reference: 19590004 - Science. 2009 Jul 10;325(5937):210-3 – reference: 10227103 - Schizophr Res. 1999 May 4;37(1):1-11 – reference: 17765738 - Prog Brain Res. 2007;163:567-76 – reference: 18495356 - Neuroscience. 2008 Jun 23;154(2):701-9 – reference: 19136031 - Behav Brain Res. 2009 Dec 7;204(2):313-21 – reference: 16469941 - Schizophr Bull. 2006 Apr;32(2):200-2 – reference: 16256957 - Biol Psychiatry. 2006 Mar 15;59(6):546-54 – reference: 12598640 - J Neurosci. 2003 Feb 15;23(4):1517-23 – reference: 8292674 - Biol Psychiatry. 1993 Nov 15;34(10):702-12 – reference: 15271491 - Trends Neurosci. 2004 Aug;27(8):447-52 – reference: 17962542 - Science. 2007 Oct 26;318(5850):576-7 – reference: 8925344 - Psychiatr Serv. 1996 Jan;47(1):41-5 – reference: 15205886 - Psychopharmacology (Berl). 2004 Jun;174(1):151-62 – reference: 11483296 - Neuroscience. 2001;105(1):7-17 – reference: 9134598 - Schizophr Res. 1997 Apr 11;24(3):365-7 – reference: 16672647 - J Neurosci. 2006 May 3;26(18):4752-62 – reference: 12237790 - Pharmacopsychiatry. 2002 Sep;35(5):190-4 – reference: 15725430 - J Psychiatr Res. 2005 May;39(3):311-23 – reference: 8366351 - J Neurosci. 1993 Sep;13(9):3916-25 – reference: 5886931 - Nature. 1965 Aug 28;207(5000):953-6 – reference: 16415915 - Mol Psychiatry. 2006 May;11(5):514-22 – reference: 15225971 - Neurosci Biobehav Rev. 2004 May;28(3):273-83 – reference: 14523382 - Nat Rev Neurosci. 2003 Oct;4(10):829-39 – reference: 10219775 - Brain. 1999 Apr;122 ( Pt 4):593-624 – reference: 16357100 - Am J Physiol Regul Integr Comp Physiol. 2006 May;290(5):R1345-56 – reference: 10071707 - Biol Psychiatry. 1999 Feb 15;45(4):395-402 – reference: 16262631 - Eur J Neurosci. 2005 Oct;22(8):1916-27 – reference: 17519367 - Neuroscientist. 2007 Jun;13(3):241-56 – reference: 17123784 - Schizophr Res. 2007 Feb;90(1-3):1-14 – reference: 18382230 - Curr Opin Psychiatry. 2008 May;21(3):290-5 – reference: 10399932 - Neuron. 1999 Jun;23(2):247-56 – reference: 11875571 - Nature. 2002 Feb 28;415(6875):1030-4 – reference: 18982002 - Mol Psychiatry. 2009 Aug;14 (8):764-73, 739 – reference: 12845415 - Psychopharmacology (Berl). 2003 Sep;169(3-4):398-403 – reference: 19442688 - Neurosci Biobehav Rev. 2009 Jul;33(7):1061-79 – reference: 7657555 - Histochem J. 1995 May;27(5):339-69 – reference: 18793679 - Behav Brain Res. 2009 Jan 30;197(1):210-8 – reference: 17341843 - J Pharmacol Sci. 2007 Mar;103(3):299-308 – reference: 10226773 - Hippocampus. 1999;9(2):118-36 – reference: 14714218 - J Neural Transm (Vienna). 2004 Jan;111(1):91-100 – reference: 17303747 - Science. 2007 Feb 16;315(5814):961-6 – reference: 9406905 - Psychiatry Res. 1997 Oct 10;72(3):161-6 – reference: 17765718 - Prog Brain Res. 2007;163:167-81 – reference: 19369317 - Am J Psychiatry. 2009 Jun;166(6):683-90 – reference: 522981 - Neuropsychologia. 1979;17(6):669-82 – reference: 11861174 - Curr Opin Neurobiol. 2002 Feb;12(1):115-8 – reference: 11921387 - Ment Retard Dev Disabil Res Rev. 2002;8(1):51-7 – reference: 18023140 - Brain Behav Immun. 2008 May;22(4):469-86 – reference: 17426354 - Neuroinformatics. 2007 Spring;5(1):79-94 – reference: 14574675 - J Comp Neurol. 2003 Dec 1;467(1):1-10 |
| SSID | ssj0000484 ssj0068394 |
| Score | 2.2835069 |
| Snippet | Background
Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such... Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such cognitive... Background: Converging evidence indicates that prenatal exposure to immune challenge can induce long-term cognitive deficits relevant to schizophrenia. Such... |
| SourceID | proquest pubmed pascalfrancis crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 531 |
| SubjectTerms | Adult and adolescent clinical studies Animals Antipsychotic Agents - pharmacology Antipsychotic Agents - therapeutic use Biological and medical sciences Biomedical and Life Sciences Biomedicine Cell Count - methods Clozapine - administration & dosage Clozapine - pharmacology Clozapine - therapeutic use Cognition & reasoning Disease Models, Animal Female Hippocampus - drug effects Hippocampus - physiology Infections Male Medical sciences Memory Disorders - chemically induced Memory Disorders - complications Memory Disorders - drug therapy Memory Disorders - physiopathology Memory, Short-Term - drug effects Mice Mice, Inbred C57BL Neurogenesis - drug effects Neurogenesis - physiology Neuropharmacology Neurosciences Original Investigation Pharmacology. Drug treatments Pharmacology/Toxicology Polynucleotides - adverse effects Pregnancy Pregnancy Complications, Infectious - immunology Pregnancy Complications, Infectious - therapy Prenatal development Prenatal Exposure Delayed Effects - chemically induced Prenatal Exposure Delayed Effects - drug therapy Prenatal Exposure Delayed Effects - immunology Prenatal Exposure Delayed Effects - psychology Psychiatry Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Psychoses Psychotropic drugs Rodents Schizophrenia |
| SummonAdditionalLinks | – databaseName: SpringerLink Journals (ICM) dbid: U2A link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1ba9RAFB60gggiWm-xWuZB-qAdyGZumcciliJU-tCFvoVJZkYXttlgssj6E_zVnjO5UawFH0PmJCTnnDn3bwh5n3ltSuMCczpwJrRSLBdeMB0Q6iNTxsZu9_Ov6mwpvlzJq2GOux273ceSZNypp2E3NEecRfh-LQVT98kDCaE79vEts5N5-xU4edlfKDD_PQ4zxykymY91zdued8MyPW5sCz8p9Kdb3OZ-_lU6jRbp9Cl5MriS9KTn_TNyz9f75OH5UCzfJ0cXPSz17phezlNW7TE9ohczYPXuOfk9IOTSar35ZRsgplP_OV3FrINvKYJfYq6Hjv1bNYN4HiTD0Z99xp1eY9vujjqPsBRdSzHJu9l2SBFPQsE1EfCDfl81DVhR2IvWNEJqfsM9d9W-IMvTz5efzthwRgOrpFh0bKEkd1UwTkEgFUJZgv233gRuLDcqD0JY60HxM6dkaStbSV8tROadLDOn08Bfkr16U_vXhLpM8lBCAChCKhY65M5rUS0C-Eh5BX5EQtKRP0U1AJjjORrrYoJejiwtgKUFsrQAkg8TSdOjd9y1-PAG0yeKDGHieJ4n5GCUgmLQ9LYAF8korY1OCJ3ugopi3cXWfrNtC81jnMrzO5YIlWLomCbkVS9e89sjJFpmEvJxlLf57f_8mDf_tfqAPOq7IrC37i3Z635s_TtwtrryMCrXH5vrIik priority: 102 providerName: Springer Nature |
| Title | Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis |
| URI | https://link.springer.com/article/10.1007/s00213-009-1754-6 https://www.ncbi.nlm.nih.gov/pubmed/20041229 https://www.proquest.com/docview/218967797 https://www.proquest.com/docview/734261938 https://www.proquest.com/docview/746048750 |
| Volume | 208 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3di9NAEB-8FkQQ0fMrnpZ9kHvQC-Zjs5s8SSuth3KlyBXqU0iyu1qoSTQpUv8E_2p3Nl8cap9CyA6bZGZn52t_A_DSkzxKI6FswZVvU86YHVJJba4Q6sNjUWKq3a-W7HJNP2yCTVubU7VllZ1ONIpaFBnGyN_orShinEf8bfndxqZRmFxtO2icwFhr4DAYwXg2X64-DaqY4inM5oZpU6DBZPbxRFkQdjlOx0CKetjlAFsD8IDa7MYudbdMKv3DVNPp4l-m6F9pVLM7Le7DvdasJNNGDh7ALZmfwu2rNnF-CuerBqL6cEGuhxNX1QU5J6sBvPrwEH63aLkk2xW_klITk74WnWxNBEJWBIEwMe5Dulqu3Na-vZYSQX420XfyDUt4D0RIhKioK4IB32JfI4XpioJjDPgH-botS72jar20IwZe8wvq3231CNaL-fW7S7vt12BnAXVr22WBLzIVCaadKqXSVNsCiYyUHyV-xEJFaZJIrQQ8wYI0yZIskJlLPSmC1BPcUf5jGOVFLp8CEV7gq1Q7g1Q51OUqFJLTzFXaXgozbVNY4HT8ibMWzBx7auziHobZsDTWLI2RpbEmedWTlA2Sx7HBkxtM7yk8hIzzw9CCs04K4nbVV3EvoxaQ_qlerpiDSXJZ7KuY-8Zn9cMjQyhz0I10LHjSiNcwu4FH8yILXnfyNsz-3495dvRdz-BOUxGBdXXPYVT_2MsX2tCq0wmc8A2fwHi6mM2WeH3_-eN80i4y_XTtTf8AAeQrrg |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELZKKwESQlBeS6H4AD1AIxLHseMDQjxabWl3tUJbqbc0iW1YackGsqtq-Qn8F_4jM85jVQF76zGKJw_NeGY8j28Iec6MVJnS1tPShh6XQngxN9yTFqE-mFCpq3YfDEX_lH86i842yO-2FwbLKlud6BS1nuUYI38NpkgJKZV8W373cGgUJlfbCRq1VByb5QWc2Ko3Rx-BvS8YOzwYf-h7zVABL494MPcCEYU6t0oL8PytzTIwWKlRNlRpqERsOU9TA5LKtIiyNE_zyOQBZ0ZHGdPStyE89xrZAi9DwSbaen8wHH1eqX6OXZ_1hQDXo8aADrGDLYrbnKrvIEwZTlXAUQQy4p64ZBVvlWkFDLL1ZI1_ub5_pW2dNTy8Q243bix9V8vdXbJhim1yfdAk6rfJ3qiGxF7u0_Gqw6vap3t0tALLXt4jvxp0XppPZz_TEohpV_tOJy7iYSqKwJsYZ6Jt7VjhTQoNUqnpRR3tp9-wZHhJtUFIjHlFMcA8W8yRwk1hwTUObIR-nZQlWHDQg1Pq4Dy_oL6fVPfJ6ZWw8gHZLGaFeUSoZlFoMzh8cuvzQNpYG8nzwIJ_Fufgw_SI3_InyRvwdJzhMU062GfH0gRYmiBLEyB52ZGUNXLIusW7l5jeUTCEqAvjuEd2WilIGi1TJd2e6BHa3QX1gDmftDCzRZXI0J2Rw3jNEi58PLb6PfKwFq_V2x0cG1M98qqVt9Xb__szj9d-6zNyoz8enCQnR8PjHXKzrsbAmr4nZHP-Y2GegpM3z3abrUXJ-VXv5j-ZoGVb |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB6VVKqQEILyCoWyB-gBatVZr3ftA0JAG7WUVhFqpd6M7d2FSMExOFEVfgL_iH_HzPoRVUBuPVre8UMzO-_9BuA5NyrOYm09rWzgCSWlFwkjPGUJ6oPLOHXd7ien8vBcfLgIL9bgd3sWhtoqW53oFLWe5pQj30NTFEulYrVnm66I0f7wTfndowFSVGhtp2nUEnJsFpcYvVWvj_aR1S84Hx6cvT_0mgEDXh6KwcwbyDDQuY21xCjA2ixD45Wa2AZxGsQyskKkqUGp5VqGWZqneWjygeBGhxnXyrcBPvcGrCs0ilEP1t8dnI4-Lc2AoBOg9YVEN6TGgw7oNFsYtfVV38GZcpqwQGMJVCg8ecVC3irTCpll6ykb_3KD_yrhOss4vAO3G5eWva1l8C6smWITNk6aov0m7IxqeOzFLjtbnvaqdtkOGy2Bsxf34FeD1MvyyfRnWiIx6_rg2dhlP0zFCISTck6s7SMrvHGhUUI1u6wz_-wbtQ8vmDYEjzGrGCWbp_MZUbiJLLTGAY-wr-OyRGuOOnHCHLTnF9L94-o-nF8LKx9Ar5gW5hEwzcPAZhiICuuLgbKRNkrkA4u-WpSjP9MHv-VPkjdA6jTPY5J0ENCOpQmyNCGWJkjysiMpaxSRVYu3rzC9o-AEVxdEUR-2WilIGo1TJd3-6APr7qKqoPpPWpjpvEpU4OLlIFqxREifQli_Dw9r8Vq-3UGz8bgPr1p5W779vz_zeOW3PoMN3MXJx6PT4y24WTdmUHvfE-jNfszNU_T3Ztl2s7MYfL7uzfwHG3Bphw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Chronic+clozapine+treatment+improves+prenatal+infection-induced+working+memory+deficits+without+influencing+adult+hippocampal+neurogenesis&rft.jtitle=Psychopharmacologia&rft.au=MEYER%2C+Urs&rft.au=KNUESEL%2C+Irene&rft.au=NYFFELER%2C+Myriel&rft.au=FELDON%2C+Joram&rft.date=2010-03-01&rft.pub=Springer&rft.issn=0033-3158&rft.volume=208&rft.issue=4&rft.spage=531&rft.epage=543&rft_id=info:doi/10.1007%2Fs00213-009-1754-6&rft.externalDBID=n%2Fa&rft.externalDocID=22393388 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0033-3158&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0033-3158&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0033-3158&client=summon |