Early flexible endoscopic evaluation of swallowing after mechanical thrombectomy in stroke patients

• Published in: Annals of clinical and translational neurology Vol. 11; no. 3; pp. 757 - 767
• Main Authors: Pinho, João, Meyer, Tareq, Mall, Bettina, Maring, Bettina, Döpp, Annalena, Becker, Johanna, Wehner, Anneke, Thissen, Sara, Schumann‐Werner, Beate, Nikoubashman, Omid, Wiesmann, Martin, Schulz, Jörg. B., Werner, Cornelius J., Reich, Arno
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2024; John Wiley and Sons Inc; Wiley
• Subjects: Aged; Anesthesia; Brain Ischemia - complications; Contraindications; Deglutition; Deglutition Disorders - diagnosis; Deglutition Disorders - etiology; Dysphagia; Endoscopy; Extubation; Female; Humans; Ischemia; Male; Patients; Pneumonia; Quality of Life; Sinuses; Stroke; Swallowing; Thrombectomy - adverse effects
• ISSN: 2328-9503; 2328-9503
• DOI: 10.1002/acn3.51998

Objective The aims of the study were to (1) characterize the findings of flexible endoscopic evaluation of swallowing (FEES) in stroke patients undergoing mechanical thrombectomy (MT); (2) analyse the screening performance of the Standardized Swallowing Assessment (SSA); and (3) study the impact of FEES‐defined dysphagia on 3‐month outcomes. Methods This single‐centre study was based on a local registry of consecutive acute ischaemic stroke patients undergoing MT during a 1‐year period. Patients received FEES within 5 days of admission regardless of the result of dysphagia screening. We compared baseline demographic and clinical characteristics of patients with and without FEES‐defined dysphagia. We collected 3‐month modified Rankin Scale (mRS) and individual index values of the European Quality of Life 5 Dimensions (EQ‐5D‐iv). Using univariable and multivariable regression analyses we predicted 3‐month outcomes for presence of dysphagia and for FEES‐defined dysphagia severity. Results We included 137 patients with a median age of 74 years, 43.1% were female, median NIHSS was 12 and successful recanalization was achieved in 92.7%. Stroke‐associated pneumonia occurred in 8% of patients. FEES‐defined dysphagia occurred in 81% of patients. Sensitivity of the SSA as a dysphagia screening was 67%. Presence of dysphagia and increasing severity of dysphagia were independently associated with increasing 3‐month mRS score. Increasing dysphagia severity dysphagia was independently associated with lower EQ‐5D‐iv. Interpretation Early FEES‐defined dysphagia occurs in four in every five patients undergoing MT. SSA has a suboptimal dysphagia screening performance. Presence of dysphagia and increasing dysphagia severity predict worse functional outcome and worse health‐related quality‐of‐life.