Marine Bromotyrosine Derivatives in Spotlight: Bringing Discoveries and Biological Significance

The Verongida order comprises several sponge families, such as Aplysinellidae, Aplysinidae, Ianthellidae, and Pseudoceratinidae, reported for producing bromotyrosine-derived compounds. First identified in 1913, bromotyrosine derivatives have since captivated interest notably for their antitumor and...

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Bibliographic Details
Published inMarine drugs Vol. 22; no. 3; p. 132
Main Authors Ferreira Montenegro, Paula, Pham, Giang Nam, Abdoul-Latif, Fatouma Mohamed, Taffin-de-Givenchy, Elisabeth, Mehiri, Mohamed
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 01.03.2024
MDPI
Subjects
Animals
anticancer activities
Anticancer properties
antimicrobial activities
Antitumour agents
Bandages
Biosynthesis
bromotyrosine derivatives
Humans
Identification and classification
marine sponges
Metabolites
Molecular weight
Porifera
Properties
Review
Tyrosine
Tyrosine - analogs & derivatives
Verongida
Djibouti
France
Brazil
Australia
Japan
Great Barrier Reef
North Stradbroke Island
India
bromotyrosine derivatives
anticancer activities
Verongida
antimicrobial activities
marine sponges
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Summary:The Verongida order comprises several sponge families, such as Aplysinellidae, Aplysinidae, Ianthellidae, and Pseudoceratinidae, reported for producing bromotyrosine-derived compounds. First identified in 1913, bromotyrosine derivatives have since captivated interest notably for their antitumor and antimicrobial properties. To date, over 360 bromotyrosine derivatives have been reported. Our review focuses specifically on bromotyrosine derivatives newly reported from 2004 to 2023, by summarizing current knowledge about their chemical diversity and their biological activities.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1660-3397
1660-3397
DOI:10.3390/md22030132