Pharmacological Activities of Schiff Bases and Their Derivatives with Low and High Molecular Phosphonates

This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, namely, potent candidates with antibacterial and anti...

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Published inPharmaceuticals (Basel, Switzerland) Vol. 16; no. 7; p. 938
Main Authors Tsacheva, Ivelina, Todorova, Zornica, Momekova, Denitsa, Momekov, Georgi, Koseva, Neli
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 28.06.2023
MDPI
Subjects
aminophophonates
anthracene-containing schiff bases
Anti-infective agents
Antimicrobial agents
Antimitotic agents
Antineoplastic agents
Antioxidants
Biological activity
Cancer
Chemical properties
Chemistry
Drugs
E coli
furan-containing Schiff bases
Furans
Health aspects
Ligands
Pharmaceuticals
pharmacological activities
Pharmacology, Experimental
Phosphonates
poly(aminophosphonate)s
Review
Schiff bases
Streptococcus infections
Bulgaria
pharmacological activities
furan-containing Schiff bases
poly(aminophosphonate)s
anthracene-containing schiff bases
aminophophonates
Online AccessGet full text
ISSN1424-8247
1424-8247
DOI10.3390/ph16070938

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Abstract This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, namely, potent candidates with antibacterial and antifungal activity, antioxidant and chemosensing properties. These advantageous properties are enhanced upon metal complexing. The subject of the review has been extended with a brief discussion on reactivity of Schiff bases with hydrogen phosphonates and the preparation of low and high molecular phosphonates, as well as their application as pharmacological agents. This work will be of interest for scientists seeking new challenges in discovering advanced pharmacological active molecules gaining inspiration from the versatile families of imines and aminophosphonates.
AbstractList This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, namely, potent candidates with antibacterial and antifungal activity, antioxidant and chemosensing properties. These advantageous properties are enhanced upon metal complexing. The subject of the review has been extended with a brief discussion on reactivity of Schiff bases with hydrogen phosphonates and the preparation of low and high molecular phosphonates, as well as their application as pharmacological agents. This work will be of interest for scientists seeking new challenges in discovering advanced pharmacological active molecules gaining inspiration from the versatile families of imines and aminophosphonates.
This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, namely, potent candidates with antibacterial and antifungal activity, antioxidant and chemosensing properties. These advantageous properties are enhanced upon metal complexing. The subject of the review has been extended with a brief discussion on reactivity of Schiff bases with hydrogen phosphonates and the preparation of low and high molecular phosphonates, as well as their application as pharmacological agents. This work will be of interest for scientists seeking new challenges in discovering advanced pharmacological active molecules gaining inspiration from the versatile families of imines and aminophosphonates.This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal ions The paper also provides a brief overview on a variety of biological applications, namely, potent candidates with antibacterial and antifungal activity, antioxidant and chemosensing properties. These advantageous properties are enhanced upon metal complexing. The subject of the review has been extended with a brief discussion on reactivity of Schiff bases with hydrogen phosphonates and the preparation of low and high molecular phosphonates, as well as their application as pharmacological agents. This work will be of interest for scientists seeking new challenges in discovering advanced pharmacological active molecules gaining inspiration from the versatile families of imines and aminophosphonates.
Audience Academic
Author Tsacheva, Ivelina
Todorova, Zornica
Momekova, Denitsa
Momekov, Georgi
Koseva, Neli
AuthorAffiliation 4 Bulgarian Academy of Sciences, 1 “15 Noemvri” Str., 1040 Sofia, Bulgaria
2 Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria
1 Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev Street, 1113 Sofia, Bulgaria
3 Department of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University of Sofia, 1000 Sofia, Bulgaria
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Keywords pharmacological activities
furan-containing Schiff bases
poly(aminophosphonate)s
anthracene-containing schiff bases
aminophophonates
Language English
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Snippet This review paper is focused on the design of anthracene and furan-containing Schiff bases and their advanced properties as ligands in complex transition metal...
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StartPage 938
SubjectTerms aminophophonates
anthracene-containing schiff bases
Anti-infective agents
Antimicrobial agents
Antimitotic agents
Antineoplastic agents
Antioxidants
Biological activity
Cancer
Chemical properties
Chemistry
Drugs
E coli
furan-containing Schiff bases
Furans
Health aspects
Ligands
Pharmaceuticals
pharmacological activities
Pharmacology, Experimental
Phosphonates
poly(aminophosphonate)s
Review
Schiff bases
Streptococcus infections
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Title Pharmacological Activities of Schiff Bases and Their Derivatives with Low and High Molecular Phosphonates
URI https://www.ncbi.nlm.nih.gov/pubmed/37513849
https://www.proquest.com/docview/2843085235
https://www.proquest.com/docview/2844096836
https://pubmed.ncbi.nlm.nih.gov/PMC10386503
https://doaj.org/article/f0d361551d9a4f9b80b428d62ecf019a
Volume 16
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