Epidemiology of genital infections caused by Mycoplasma hominis, M. genitalium and Ureaplasma urealyticum in Iran; a systematic review and meta-analysis study (2000–2019)
Abstract Background Although many species of mycoplasmas regard as normal flora, but some species causes serious genital disease. In Iran several epidemiological studies have documented the prevalence of Mycoplasma hominis, M. genitalium and Ureaplasma urealyticum in genital disorders. This meta-ana...
Saved in:
Published in | BMC public health Vol. 20; no. 1; pp. 1 - 1020 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
London
BioMed Central Ltd
29.06.2020
BioMed Central BMC |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Abstract
Background
Although many species of mycoplasmas regard as normal flora, but some species causes serious genital disease. In Iran several epidemiological studies have documented the prevalence of
Mycoplasma hominis, M. genitalium
and
Ureaplasma urealyticum
in genital disorders. This meta-analysis is going to represent the prevalence of
M. hominis, M. genitalium
and
U. urealyticum
among Iranian couples and the correlation between mycoplasmas infection and infertility.
Methods
We search online databases from January 2000 to June 2019. We used following MeSH keywords (Prevalence,
M. hominis, M. genitalium, U. urealyticum
, male, female, fertility, Infertility, genitourinary tract infection and Iran) with all possible combinations with “OR” and “AND”. Finally, forty-four articles from 2670 were chosen for data extraction and analysis by software using STATA version 14.0.
Results
This meta-analysis revealed that the prevalence of
U. urealyticum
was 17.53% in Iran and the prevalence of
M. genitalium
and
M. hominis
were 11.33 and 9.68% respectively. The rate of
M. genitalium
,
M. hominis
and
U. urealyticum
infection in women with symptoms of genitourinary tract infection was higher than men with genitourinary tract infection (6.46% vs 5.4, 7.67% vs 5.88 and 21.04% vs 12.13%, respectively). As expected, the prevalence of
M. genitalium
,
U. urealyticum
and
M. hominis
among infertile women (12.73, 19.58 and 10.81%) were higher than fertile women (3%, 10. 85% and 4. 35%). Similarly, the prevalence of
M. hominis
and
U. urealyticum
among infertile men (14 and 21.18%) were higher than fertile men (4 and 3%). Based on this analysis, the rate of
U. urealyticum
was higher than
M. genitalium
and
M. hominis
among infertile men and women compared to the fertile group. The prevalence rate of
M. genitalium
,
M. hominis
and
U. urealyticum
in central provinces is higher than other parts of Iran.
Conclusions
This meta-analysis reemphasizes a significant relationship between the infertility rate and
U. urealyticum
,
M. genitalium
and
M. hominis
infections. Our finding help to plan the prevalence map of
M. hominis, M. genitalium
and
U. urealyticum
in Iran but further studies are needed to suggest routine screening of the pathogens. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3 |
ISSN: | 1471-2458 1471-2458 |
DOI: | 10.1186/s12889-020-08962-5 |