Magnetic cilia carpets with programmable metachronal waves

• Published in: Nature communications Vol. 11; no. 1; p. 2637
• Main Authors: Gu, Hongri, Boehler, Quentin, Cui, Haoyang, Secchi, Eleonora, Savorana, Giovanni, De Marco, Carmela, Gervasoni, Simone, Peyron, Quentin, Huang, Tian-Yun, Pane, Salvador, Hirt, Ann M., Ahmed, Daniel, Nelson, Bradley J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.05.2020; Nature Publishing Group; Nature Portfolio
• Subjects: 639/166; 639/766/189; 639/766/25; 639/766/747; Artificial Cells - ultrastructure; Biological activity; Biomedical materials; Carpets; Cilia; Cilia - physiology; Cilia - ultrastructure; Composite materials; Computer Simulation; Humanities and Social Sciences; Hydrodynamics; Locomotion; Magnetic fields; Magnetics; Magnetization; Microfluidics; Models, Biological; Motion; multidisciplinary; Printing, Three-Dimensional - instrumentation; Pumping; Robotics; Robotics - instrumentation; Science; Science (multidisciplinary); Solid surfaces; Transport processes; Waves
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/s41467-020-16458-4

Metachronal waves commonly exist in natural cilia carpets. These emergent phenomena, which originate from phase differences between neighbouring self-beating cilia, are essential for biological transport processes including locomotion, liquid pumping, feeding, and cell delivery. However, studies of such complex active systems are limited, particularly from the experimental side. Here we report magnetically actuated, soft, artificial cilia carpets. By stretching and folding onto curved templates, programmable magnetization patterns can be encoded into artificial cilia carpets, which exhibit metachronal waves in dynamic magnetic fields. We have tested both the transport capabilities in a fluid environment and the locomotion capabilities on a solid surface. This robotic system provides a highly customizable experimental platform that not only assists in understanding fundamental rules of natural cilia carpets, but also paves a path to cilia-inspired soft robots for future biomedical applications. Synthetic hair-like structures (cilia) controlled by an external field have been developed, especially for microfluidic applications. Here, Gu et al. make soft artificial cilia carpets with programmable magnetization patterns and utilize them to achieve pumping and locomotion in a soft robotic model.