Trends in mortality rate in patients with congenital heart disease undergoing noncardiac surgical procedures at children’s hospitals

• Published in: Scientific reports Vol. 11; no. 1; p. 1543
• Main Authors: Nasr, Viviane G., Staffa, Steven J., Faraoni, David, DiNardo, James A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 15.01.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 692/699/75/1539; 692/700/1720; Cardiovascular disease; Cardiovascular diseases; Children; Congenital diseases; Coronary artery disease; Heart diseases; Heart surgery; Hospitals; Humanities and Social Sciences; Mortality; multidisciplinary; Patients; Pediatrics; Science; Science (multidisciplinary); Survival
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-021-81161-3

Advances made in pediatric cardiology, cardiac surgery and critical care have significantly improved the survival rate of patients with congenital heart disease (CHD) leading to an increase in children with CHD presenting for noncardiac surgical procedures. This study aims (1) to describe the trend and perioperative mortality rates in patients with CHD undergoing noncardiac surgical procedures at children’s hospitals over the past 5 years and (2) to describe the patient characteristics and the most common type of surgical procedures. The Pediatric Health Information System (PHIS) is an administrative database that contains inpatient, observation, and outpatient surgical data from 52 freestanding children’s hospitals. Thirty-nine of the 52 hospitals submitted data on all types of patient encounters for the duration of the study from 2015 to 2019. The total numbers of non-cardiac surgical encounters among patients with history of a CHD diagnosis significantly increased each year from 38,272 in 2015 to 45,993 in 2019 (P < 0.001). Despite the increase in case numbers, there has been a significant decline in mortality rates to the most recent incidence of 1.06% in 2019. Careful patient selection and medical optimization of patients aligned with specific expertise at dedicated children’s hospitals may lead to improvement in mortality rate. Future studies comparing the outcomes of patients with cardiac disease based on hospital type and volume as well as type of providers may help determine the future of care including potential need for regionalization of noncardiac care for this vulnerable patient population.