Primary clear cell adenocarcinoma of the pancreas: a case report and literature update

Primary clear cell carcinoma of pancreas is extremely rare. We present a case of a 64-year-old male with a mass in the distal body and tail of the pancreas. He underwent a distal pancreatectomy. The histopathology of tumor cells showed features with abundant clear cytoplasm and prominent cell bounda...

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Bibliographic Details
Published inOncoTargets and therapy Vol. 11; pp. 8197 - 8200
Main Authors Sun, Pi-Jiang, Yu, Yan-Hua, Cui, Xi-Jun
Format Journal Article
LanguageEnglish
Published New Zealand Dove Medical Press Limited 01.01.2018
Taylor & Francis Ltd
Dove Medical Press
Subjects
Abdomen
Adenocarcinoma
Analysis
Antibodies
Antigen-antibody reactions
Antigens
Biomarkers
Carcinoma
Case Report
Case reports
Clear cell carcinoma
Cytoplasm
Health aspects
Histochemistry
Keratin
Kidney cancer
Literature reviews
Medical prognosis
Metastasis
Mutation
Pancreas
Pancreatectomy
Pancreatic cancer
Pathology
Rare tumor
Surgery
Tumors
China
clear cell carcinoma
pancreas
rare tumor
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Summary:Primary clear cell carcinoma of pancreas is extremely rare. We present a case of a 64-year-old male with a mass in the distal body and tail of the pancreas. He underwent a distal pancreatectomy. The histopathology of tumor cells showed features with abundant clear cytoplasm and prominent cell boundaries. Immunohistochemical analysis of neoplastic cells showed reactions to antibodies against cytokeratin-7 and showed no reactions to antibodies against hepatocyte nuclear factor-1β, carbonic anhydrase 9, synaptophysin, and chromogranin A. The patient was subsequently diagnosed with a primary clear cell carcinoma of the pancreas. This is the first time we have encountered it. We report this rare case and update the current literature of this tumor.
ISSN:1178-6930
1178-6930
DOI:10.2147/OTT.S183054