Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

• Published in: Haematologica (Roma) Vol. 101; no. 6; pp. e232 - e236
• Main Authors: Stoddart, Angela, Qian, Zhijian, Fernald, Anthony A, Bergerson, Rachel J, Wang, Jianghong, Karrison, Theodore, Anastasi, John, Bartom, Elizabeth T, Sarver, Aaron L, McNerney, Megan E, Largaespada, David A, Le Beau, Michelle M
• Format: Journal Article
• Language: English
• Published: Italy Ferrata Storti Foundation 01.06.2016
• Subjects: Animals; DNA-Binding Proteins; Intracellular Signaling Peptides and Proteins - genetics; Intracellular Signaling Peptides and Proteins - metabolism; Leukemia, Myeloid, Acute - genetics; Leukemia, Myeloid, Acute - metabolism; Leukemia, Myeloid, Acute - pathology; Mice; Mice, Mutant Strains; Mutagenesis, Insertional; Myelodysplastic Syndromes - genetics; Myelodysplastic Syndromes - metabolism; Myelodysplastic Syndromes - pathology; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Online Only; Peptide Termination Factors - genetics; Peptide Termination Factors - metabolism; Proteins - genetics; Proteins - metabolism; Retroviridae; Transcription Factors; Wnt Signaling Pathway - genetics; insertional mutagenesis; retroviral; myeloid neoplasms; Wnt pathway; del(5q)
• ISSN: 0390-6078; 1592-8721
• DOI: 10.3324/haematol.2015.139527