Oral physiology, nutrition and quality of life in diabetic patients associated or not with hypertension and beta-blockers therapy

• Published in: Journal of oral rehabilitation Vol. 43; no. 7; pp. 511 - 518
• Main Authors: Pereira, L. J., Foureaux, R. C., Pereira, C. V., Alves, M. C., Campos, C. H., Rodrigues Garcia, R. C. M., Andrade, E. F., Gonçalves, T. M. S. V.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.07.2016
• Subjects: Adult; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; Cross-Sectional Studies; dental physiological phenomena; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - physiopathology; Diabetes Mellitus, Type 2 - psychology; DMF Index; Female; Humans; Hypertension - complications; Hypertension - physiopathology; Hypertension - psychology; Jaw, Edentulous, Partially - physiopathology; Male; Mastication - drug effects; Mastication - physiology; Middle Aged; oral health; Quality of Life; Risk Factors; saliva; Saliva - drug effects; Saliva - secretion; Xerostomia - physiopathology; saliva; oral health; dental physiological phenomena
• ISSN: 0305-182X; 1365-2842; 1365-2842
• DOI: 10.1111/joor.12398

Summary The relationship between type 2 diabetes oral physiology, nutritional intake and quality of life has not been fully elucidated. We assessed the impact of type 2 diabetes – exclusive or associated with hypertension with beta‐blockers treatment – on oral physiology, mastication, nutrition and quality of life. This cross‐sectional study was performed with 78 complete dentate subjects (15 natural teeth and six masticatory units minimum; without removable or fixed prostheses), divided into three groups: diabetics (DM) (n = 20; 45·4 ± 9·5 years), diabetics with hypertension and receiving beta‐blockers treatment (DMH) (n = 19; 41·1 ± 5·1 years) and controls (n = 39; 44·5 ± 11·7 years) matched for gender, age and socioeconomic status. Blood glucose, masticatory performance, swallowing threshold, taste, food intake, stimulated and unstimulated salivary flow, pH and buffering capacity of saliva were assessed. Glycemia was higher in DM than in controls (P < 0·01). No differences were observed between DM and controls for nutrition and quality of life. Both stimulated and unstimulated salivary flow rate were lower in DMH (P < 0·01), which also presented the lowest number of teeth and masticatory units (P < 0·0001), and reduction in the number of chewing cycles (P < 0·01). Controls showed lower Decayed Missing Filled Teeth index (DMFT) scores in comparison with DMH (P = 0·021). Masticatory performance and saliva buffering capacity were similar among groups. Exclusive type 2 diabetes did not alter oral physiology, nutrition or quality of life. However, when hypertension and beta‐blockers treatment were associated with diabetes, the salivary flow rate, chewing cycles and number of teeth decreased.