Euglycemic diabetic ketoacidosis following major vascular surgery is a new item on the differential for postoperative acidosis

New pharmacologic advances in the treatment of diabetes include SGLT-2 inhibitors, which have been demonstrated in randomized-controlled clinical trials to reduce overall and cardiac-specific mortality and slow progression of chronic kidney disease. Euglycemic diabetic ketoacidosis is a rare but lif...

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Bibliographic Details
Published inJournal of vascular surgery cases and innovative techniques Vol. 7; no. 4; pp. 778 - 780
Main Authors Gomez-Sanchez, Clara M., Wu, Bian X., Gotts, Jeffrey E., Chang, Robert W.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.12.2021
Elsevier
Subjects
Case report
Diabetic acidosis
Peripheral artery disease
Postoperative complication
SGLT-2 inhibitors
Diabetic acidosis
Peripheral artery disease
SGLT-2 inhibitors
Postoperative complication
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Summary:New pharmacologic advances in the treatment of diabetes include SGLT-2 inhibitors, which have been demonstrated in randomized-controlled clinical trials to reduce overall and cardiac-specific mortality and slow progression of chronic kidney disease. Euglycemic diabetic ketoacidosis is a rare but life-threatening complication associated with the use of SGLT-2 inhibitors. Here we describe a case of severe euglycemic diabetic ketoacidosis after lower extremity bypass in a patient taking an SGLT-2 inhibitor. Awareness of this potential complication is essential as these novel agents are increasingly used in patients with cardiovascular disease.
ISSN:2468-4287
2468-4287
DOI:10.1016/j.jvscit.2021.10.006