The role of influenza, RSV and other common respiratory viruses in severe acute respiratory infections and influenza-like illness in a population with a high HIV sero-prevalence, South Africa 2012–2015

• Published in: Journal of clinical virology Vol. 75; pp. 21 - 26
• Main Authors: Pretorius, Marthi A, Tempia, Stefano, Walaza, Sibongile, Cohen, Adam L, Moyes, Jocelyn, Variava, Ebrahim, Dawood, Halima, Seleka, Mpho, Hellferscee, Orienka, Treurnicht, Florette, Cohen, Cheryl, Venter, Marietjie
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.02.2016
• Subjects: Adenoviridae; Adenovirus; Allergy and Immunology; Controls; Disease association; Enterovirus; HIV; HIV Infections - blood; HIV Infections - complications; HIV Seropositivity; Human immunodeficiency virus; Human metapneumovirus; Humans; Infectious Disease; Influenza like illness; Influenza virus; Influenza, Human - blood; Influenza, Human - virology; Orthomyxoviridae; Parainfluenza virus; Pneumonia; Prevalence; Respiratory syncytial virus; Respiratory virus infection; Respirovirus; Rhinovirus; Severe acute respiratory illness; Severe Acute Respiratory Syndrome - epidemiology; Severe Acute Respiratory Syndrome - etiology; Severe Acute Respiratory Syndrome - virology; South Africa; South Africa; Pneumonia; Severe acute respiratory illness; HIV; Respiratory virus infection; Controls; South Africa; Influenza like illness; Disease association
• ISSN: 1386-6532; 1873-5967
• DOI: 10.1016/j.jcv.2015.12.004

Highlights • Detection rate attributable to illness reflects a more accurate description of the prevalence of viruses causing respiratory disease. • Influenza, RSV and hMPV considered pathogens if detected with PCR patients with Influenza like illness or severe acute respiratory illness. • Rhinovirus and adenovirus identified among controls suggesting that they may cause only a proportion of clinical disease.