Effect of artemether-lumefantrine (Coartem) on cytomegalovirus urine viral load during and following treatment for malaria in children

Highlights • CMV shedding is common in Mali, a malaria-endemic area. • Most children have low level of CMV shedding in the urine. • Artemisinin-based therapy for malaria may decrease CMV shedding in urine.

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Bibliographic Details
Published inJournal of clinical virology Vol. 77; pp. 40 - 45
Main Authors Barger-Kamate, Breanna, Forman, Michael, Sangare, Cheik Oumar, Haidara, Aboubecrin Sedhigh A, Maiga, Hamma, Vaidya, Dhananjay, Djimde, Abdoulaye, Arav-Boger, Ravit
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.04.2016
Subjects
Allergy and Immunology
Artemether-lumefantrine
Artemisinins - therapeutic use
Child
Child, Preschool
Coinfection
Cytomegalovirus
Cytomegalovirus Infections - diagnosis
Cytomegalovirus Infections - virology
Drug Combinations
Ethanolamines - therapeutic use
Female
Fluorenes - therapeutic use
Follow-Up Studies
Humans
Infant
Infectious Disease
Malaria
Malaria - diagnosis
Malaria - drug therapy
Malaria - parasitology
Male
Parasite Load
Treatment Outcome
Urine viral load
Viral Load
Virus Shedding
Mali
Cytomegalovirus
Malaria
Urine viral load
Artemether-lumefantrine
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Summary:Highlights • CMV shedding is common in Mali, a malaria-endemic area. • Most children have low level of CMV shedding in the urine. • Artemisinin-based therapy for malaria may decrease CMV shedding in urine.
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Breanna Barger-Kamate and Michael Forman are co-primary authors
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2016.02.006