Time course of hemorheological alterations after heavy anaerobic exercise in untrained human subjects

• Published in: Journal of applied physiology (1985) Vol. 94; no. 3; pp. 997 - 1002
• Main Authors: Yalcin, Ozlem, Erman, Alpaslan, Muratli, Sedat, Bor-Kucukatay, Melek, Baskurt, Oguz K
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Am Physiological Soc 01.03.2003; American Physiological Society
• Subjects: Adult; Anaerobiosis - physiology; Biological and medical sciences; Blood; Cardiovascular system; Cell Aggregation - physiology; Circulatory system; Erythrocyte Count; Erythrocyte Deformability - physiology; Erythrocytes; Erythrocytes - physiology; Exercise; Exercise - physiology; Fundamental and applied biological sciences. Psychology; Granulocytes - physiology; Humans; Lactic Acid - blood; Leukocyte Count; Male; Physical Fitness - physiology; Respiratory Burst - physiology; Rheology; Time & motion studies; Time Factors; Vertebrates: blood, hematopoietic organs, reticuloendothelial system; Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports; Physical exercise; Human; granulocyte activation; Deformability; Rheology; Intensity; Bicycle ergometer; Granulocyte; erythrocyte aggregation; Red blood cell; Activation; Aggregation; Wingate test; Blood cell; erythrocyte deformability
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/japplphysiol.00368.2002

1  Department of Physiology, Akdeniz University School of Medicine, and 2  School of Physical Education and Sports, Akdeniz University, Antalya, Turkey 07070 The time course of hemorheological alterations was investigated after heavy anaerobic exercise in untrained male human subjects. The Wingate protocol was performed by each subject, and blood lactate, red blood cell (RBC) deformability and aggregation, white blood cell (WBC) activation, and several hematological parameters were investigated during 24 h after the exercise and compared with preexercise values. Compared with the preexercise value, blood lactate level was found to be ~10-fold higher immediately after the exercise. There was a transient, significant increment of RBC and WBC counts immediately after exercise that was followed by a decrement of RBC count. There was a second increase of WBC count, accompanied with increased percentages of granulocytes and granulocyte activation, starting 45 min after exercise. RBC deformability was found to be impaired immediately after exercise and remained reduced for at least 12 h; RBC aggregation was also found to be decreased after exercise, with the onset of this decrease delayed by 30 min. The results of this study indicate that a single bout of heavy anaerobic exercise may induce significant hemorheological deterioration lasting for up to 12 h and thus suggest the need to consider such effects in individuals with impaired cardiovascular function. Wingate test; erythrocyte deformability; erythrocyte aggregation; granulocyte activation