Assessment of Role of Bisphosphonates on Dental Implant Treatment in Post-menopausal Ladies

• Published in: Journal of pharmacy & bioallied science Vol. 16; no. Suppl 1; pp. S748 - S750
• Main Authors: Manas, Abhigyan, Mulla, Munaz, Grover, Shubhi, Garhnayak, Mirna, Mulla, Mushir, Parihar, Anuj Singh
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.02.2024; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Alveolar bone; Analysis; bisphosphonate; Bisphosphonates; Bone density; Bone implants; Bone mineral density; Bones; Cancellous bone; Cortical bone; Density; Dental implants; Dental prosthetics; failures; implant; Implant dentures; Menopause; Original; Parathyroid hormone; Phosphonates; post-menopausal ladies; Post-menopause; Postmenopausal women; Zoledronic acid; Bisphosphonate; failures; implant; post-menopausal ladies
• ISSN: 0976-4879; 0975-7406
• DOI: 10.4103/jpbs.jpbs_992_23

To examine the impact of bisphosphonates (BPs) on dental implant treatment and alveolar bone in post-menopausal ladies. Twenty post-menopausal ladies who had at least one dental implant within the previous 5 years participated in the current study. Ten subjects were categorized into two groups: Group A had BP medication for 1.5 years, and group B received parathyroid hormone (PTH). Both groups' bone thickness and bone mineral density (BMD) were measured. Group A had 5%, and group B had 5% of dental implants failures. BMD of cortical bone was 1468 ± 136 mg/mL and 1008 ± 84 mg/mL in groups A and B, correspondingly. The cortical and cancellous bone densities in both the groups were statically significant. Cortical bone thickness was insignificant in comparison. Both cortical and cancellous bones' bone mineral density decreased in both groups. With continued usage of BPs, the cortical bone thickness increased.