Marine Pyridoacridine Alkaloids: Biosynthesis and Biological Activities

• Published in: Chemistry & biodiversity Vol. 13; no. 1; pp. 37 - 47
• Main Authors: Ibrahim, Sabrin R. M., Mohamed, Gamal A.
• Format: Journal Article
• Language: English
• Published: Zürich WILEY-VCH Verlag 01.01.2016; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Subjects: Acridines - chemistry; Acridines - metabolism; Acridines - pharmacology; Alkaloids; Alkaloids - biosynthesis; Alkaloids - chemistry; Alkaloids - pharmacology; Animals; Anti-HIV Agents - chemistry; Anti-HIV Agents - metabolism; Anti-HIV Agents - pharmacology; Anti-Infective Agents - chemistry; Anti-Infective Agents - metabolism; Anti-Infective Agents - pharmacology; Antineoplastic Agents - chemistry; Antineoplastic Agents - metabolism; Antineoplastic Agents - pharmacology; Antiparasitic Agents - chemistry; Antiparasitic Agents - metabolism; Antiparasitic Agents - pharmacology; Ascidians; Biological activity; Biosynthesis; Cell Proliferation - drug effects; Human immunodeficiency virus; Humans; Insecticides - chemistry; Insecticides - metabolism; Insecticides - pharmacology; Molecular Structure; Phenanthrolines - chemistry; Phenanthrolines - metabolism; Phenanthrolines - pharmacology; Pyridoacridine; Review; Reviews; Alkaloids; Biosynthesis; Pyridoacridine; Ascidians; Biological activity

Pyridoacridines are a class of strictly marine‐derived alkaloids that constitute one of the largest chemical families of marine alkaloids. During the last few years, both natural pyridoacridines and their analogues have constituted excellent targets for synthetic works. They have been the subject of...