Primary thyroid gland myxofibrosarcoma: a case report and review of the literature

Background Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. Case presentation We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a h...

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Published inSurgical case reports Vol. 8; no. 1; p. 139
Main Authors Stylianidi, Maria Chara, Haeberle, Lena, Schott, Matthias, Mori, Yuriko, Antke, Christina, Giesel, Frederick Lars, Antoch, Gerald, Esposito, Irene, Knoefel, Wolfram Trudo, Krieg, Andreas
Format Journal Article
LanguageEnglish
Published Berlin/Heidelberg Springer Berlin Heidelberg 25.07.2022
Springer Nature B.V
SpringerOpen
Subjects
Case Report
Case reports
Medicine
Medicine & Public Health
Myxofibrosarcoma
Radiation therapy
Sarcoma
Soft tissue sarcoma
Surgery
Thyroid gland
Tumors
Ultrasonic imaging
Soft tissue sarcoma
Myxofibrosarcoma
Thyroid gland
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Summary:Background Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland. Case presentation We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a hypoechoic thyroid nodule with microcalcifications that was highly suspicious for malignancy. He underwent a left hemithyroidectomy. Histopathological examination and immunohistochemical studies revealed a myxofibrosarcoma of the thyroid gland. Conclusion Myxofibrosarcoma of the thyroid gland is extremely rare. The diagnosis is based on histopathological features. Radical surgery achieving tumor-free resection margins remains the only chance for cure. However, the role of radiotherapy and/or chemotherapy is still under debate. Due to their high tendency for locoregional recurrence, a close follow-up after surgery is mandatory.
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ISSN:2198-7793
2198-7793
DOI:10.1186/s40792-022-01496-5