Treatment of infected left ventricular assist device using antibiotic-impregnated beads

There is no well-established therapy for treating infections of heart-assist or artificial heart devices, a serious problem with life-threatening consequences. We used a promising new approach in which antibiotic-impregnated polymethylmethacrylate beads were placed around an implanted left ventricul...

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Bibliographic Details
Published inThe Annals of thoracic surgery Vol. 67; no. 2; pp. 554 - 555
Main Authors McKellar, Stephen H, Allred, Bryce D, Marks, John D, Cowley, Cris G, Classen, David C, Gardner, Scott C, Long, James W
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier Inc 01.02.1999
Elsevier Science
Subjects
Biological and medical sciences
Cardiology. Vascular system
Combined Modality Therapy
Drug Implants
Drug Therapy, Combination - administration & dosage
Heart
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Transplantation
Heart-Assist Devices
Humans
Male
Medical sciences
Middle Aged
Polymethyl Methacrylate
Prosthesis-Related Infections - surgery
Reoperation
Staphylococcal Infections - surgery
Staphylococcus epidermidis
Tobramycin - administration & dosage
Vancomycin - administration & dosage
Human
Heart failure
Intensive cardiocirculatory care
Reoperation
Associated technique
Cardiocirculatory support
Implantation
Method
Infection
Case study
Treatment
Surgery
Bacteriosis
Complication
Superinfection
Apparatus
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Summary:There is no well-established therapy for treating infections of heart-assist or artificial heart devices, a serious problem with life-threatening consequences. We used a promising new approach in which antibiotic-impregnated polymethylmethacrylate beads were placed around an implanted left ventricular assist device to control an external blood pump infection in a bridge-to-transplant patient. In this case report, we describe the potential of antimicrobial-impregnated polymethylmethacrylate beads for in situ control of infections involving external surfaces of cardiovascular devices.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:0003-4975
1552-6259
DOI:10.1016/S0003-4975(98)01243-0