Thrombotic thrombocytopenic purpura associated with dengue and chikungunya virus coinfection: case report during an epidemic period
The present report shows the occurrence of thrombotic thrombocytopenic purpura (TTP) associated with acute dengue and chikungunya virus coinfection, manifesting as a severe disease with high mortality potential. The patient was a 28 year-old man with clinical and epidemiological diagnosis of arbovir...
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Published in | Revista do Instituto de Medicina Tropical de São Paulo Vol. 60; pp. e48 - 4 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English Portuguese |
Published |
Brazil
Instituto de Medicina Tropical de Sao Paulo
01.01.2018
Instituto de Medicina Tropical Universidade de São Paulo (USP) |
Subjects | |
Online Access | Get full text |
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Summary: | The present report shows the occurrence of thrombotic thrombocytopenic purpura (TTP) associated with acute dengue and chikungunya virus coinfection, manifesting as a severe disease with high mortality potential. The patient was a 28 year-old man with clinical and epidemiological diagnosis of arboviruses infections who developed thrombocytopenia and anemia, after which oral corticosteroid therapy was started. On the third day of hospitalization, he showed neurological alterations that simulated a cerebral vascular accident, but the imaging examination did not identify ischemic or hemorrhagic alterations. At that moment, the TTP hypothesis was raised so that plasmapheresis and corticosteroid pulse therapy were started, have been essential for the favorable evolution of the case. |
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Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3 There are no conflicts of interest between the investigators and the patient, who authorized the reporting of his case by signing the free and informed consent form. CONFLICT OF INTEREST |
ISSN: | 1678-9946 0036-4665 1678-9946 |
DOI: | 10.1590/S1678-9946201860048 |