Extensive Duplication and Reshuffling in the Arabidopsis Genome

Systematic analysis of the Arabidopsis genome provides a basis for detailed studies of genome structure and evolution. Members of multigene families were mapped, and random sequence alignment was used to identify regions of extended similarity in the Arabidopsis genome. Detailed analysis showed that...

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Bibliographic Details
Published inThe Plant cell Vol. 12; no. 7; pp. 1093 - 1101
Main Authors Blanc, Guillaume, Barakat, Abdelali, Guyot, Romain, Cooke, Richard, Delseny, Michel
Format Journal Article
LanguageEnglish
Published England American Society of Plant Physiologists 01.07.2000
American Society of Plant Biologists
Subjects
Arabidopsis - genetics
Blasts
Chromosomes
Chromosomes, Bacterial
Evolution
Exons
Gene Duplication
Genes
Genetic loci
Genome, Plant
Genomes
Genomics
Molecular Sequence Data
Plant cells
Plants
Translocation
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Summary:Systematic analysis of the Arabidopsis genome provides a basis for detailed studies of genome structure and evolution. Members of multigene families were mapped, and random sequence alignment was used to identify regions of extended similarity in the Arabidopsis genome. Detailed analysis showed that the number, order, and orientation of genes were conserved over large regions of the genome, revealing extensive duplication covering the majority of the known genomic sequence. Fine mapping analysis showed much rearrangement, resulting in a patchwork of duplicated regions that indicated deletion, insertion, tandem duplication, inversion, and reciprocal translocation. The implications of these observations for evolution of the Arabidopsis genome as well as their usefulness for analysis and annotation of the genomic sequence and in comparative genomics are discussed.
Bibliography:To whom correspondence should be addressed. E-mail cooke@univ-perp.fr; fax 33-468668499
ISSN:1040-4651
1532-298X
DOI:10.1105/tpc.12.7.1093