Evolution and Reassortment of H6 Subtype Avian Influenza Viruses

• Published in: Viruses Vol. 15; no. 7; p. 1547
• Main Authors: Lin, Mingqin, Yao, Qiu-Cheng, Liu, Jing, Huo, Miaotong, Zhou, Yan, Chen, Minyi, Li, Yuanguo, Gao, Yuwei, Ge, Ye
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.07.2023; MDPI
• Subjects: Avian flu; avian influenza virus; Avian influenza viruses; Bird migration; Control; Evolution & development; Genetic analysis; Genetic aspects; Genetic diversity; genetics and evolution; H6 subtype; Hogs; Identification and classification; Infections; Influenza; Phylogenetics; Phylogeny; Poultry; prevention and control; Public health; reassortment; Review; Viruses; China; Canada; Hunan China; Asia; Europe; Taiwan; Hong Kong China; North America; reassortment; prevention and control; H6 subtype; genetics and evolution; avian influenza virus
• ISSN: 1999-4915; 1999-4915
• DOI: 10.3390/v15071547

The H6 subtype of avian influenza virus (H6 AIV) is the most detected AIV subtype in poultry and wild birds. It causes economic losses to the poultry industry, and the most important, H6 AIV may have the ability to infect mammals, which is a great threat to public health security. In addition, the H6 subtype can serve as a precursor to providing internal genes for other highly pathogenic AIVs, posing a potential threat. H6 AIV currently face to the high positive detection rate and harmless nature of H6 AIV and because not highly effective H6 subtype vaccine available on the market. In this study, we focused on the prevalence of H6 AIV in poultry and wild birds, phylogenetic analysis, genetic variation characteristics, selection analysis, and prevention and control to provide relevant references for the scientific prevention and control of H6 AIV in future.