Dual-energy CT angiography of pelvic and lower extremity arteries: dual-energy bone subtraction versus manual bone subtraction

• Published in: Clinical radiology Vol. 64; no. 11; pp. 1088 - 1096
• Main Authors: Yamamoto, S, McWilliams, J, Arellano, C, Marfori, W, Cheng, W, Mcnamara, T, Quinones-Baldrich, W.J, Ruehm, S.G
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.11.2009; Elsevier
• Subjects: Aged; Aged, 80 and over; Algorithms; Angiography - methods; Angiography, Digital Subtraction - methods; Biological and medical sciences; Bones of Lower Extremity - diagnostic imaging; Cardiovascular system; Female; Humans; Investigative techniques, diagnostic techniques (general aspects); Lower Extremity - blood supply; Lower Extremity - diagnostic imaging; Male; Medical sciences; Middle Aged; Pelvis - blood supply; Pelvis - diagnostic imaging; Prospective Studies; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radiographic Image Interpretation, Computer-Assisted - methods; Radiography, Dual-Energy Scanned Projection - methods; Radiology; Subtraction Technique; Tomography, X-Ray Computed - methods; Nuclear medicine; Radiodiagnosis; Angiography; Radiology; Medical imagery; Computerized axial tomography; Bone; Artery; Comparative study
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/j.crad.2009.07.009

Aim To analyse the effect of dual-energy bone subtraction (DEBS) on the image quality of peripheral computed tomography (CT) angiograms. Materials and methods Twenty patients underwent dual-energy CT angiography of the pelvic and lower extremity arteries using commercially available equipment. Two different methods of image processing were employed for each CT angiographic dataset: (1) DEBS, and (2) manual bone subtraction (MBS). Effects on vessel visibility and artificial vessel alterations were compared. Results Bone removal, and the resultant visibility of vessel segments, were significantly better with DEBS than with MBS ( p = 0.011). The overall frequency of vessel-related alterations was lower in MBS compared with DEBS ( p = 0.001). Specifically, in the 249 vessel segments with calcified plaques, MBS generated fewer vessel alterations than DEBS ( p < 0.001). In the 309 vessel segments without calcified plaques, there was no difference in vessel alteration between the two techniques ( p = 0.22). Conclusion DEBS facilitates bone removal in peripheral CT angiography, but generates more vessel alterations, particularly in the presence of calcified plaque.