Remote Supramolecular Control of Catalyst Selectivity in the Hydroformylation of Alkenes

In the pocket: The supramolecular interactions between a Rh phosphine catalyst equipped with an anion‐binding pocket and alkenes that contain anionic functionalities (see picture) provide an excellent design concept to achieve remote control of the regioselectivity in hydroformylation reactions. The...

Full description

Saved in:
Bibliographic Details
Published inAngewandte Chemie (International ed.) Vol. 50; no. 2; pp. 396 - 400
Main Authors Dydio, Paweł, Dzik, Wojciech I, Lutz, Martin, de Bruin, Bas, Reek, Joost N.H
Format Journal Article
LanguageEnglish
Published Weinheim Wiley-VCH Verlag 10.01.2011
WILEY-VCH Verlag
WILEY‐VCH Verlag
Wiley
Wiley Subscription Services, Inc
EditionInternational ed. in English
Subjects
Alkenes
Alkenes - chemistry
Catalysis
Chemistry
Chemistry, Multidisciplinary
Coordination Complexes - chemistry
Crystallography, X-Ray
hydroformylation
Hydrogen Bonding
hydrogen bonds
Ligands
Molecular Conformation
molecular recognition
Physical Sciences
P ligands
Rhodium - chemistry
Science & Technology
Stereoisomerism
supramolecular catalysis
LIBRARIES
HIGH-THROUGHPUT
BIDENTATE LIGANDS
HYDROXYLATION
molecular recognition
P ligands
supramolecular catalysis
hydroformylation
hydrogen bonds
Online AccessGet full text

Cover

More Information
Summary:In the pocket: The supramolecular interactions between a Rh phosphine catalyst equipped with an anion‐binding pocket and alkenes that contain anionic functionalities (see picture) provide an excellent design concept to achieve remote control of the regioselectivity in hydroformylation reactions. The 4‐pentenoate and 3‐butenylphosphonate, which fit tightly between the Rh center and the pocket, were hydroformylated with unprecedented selectivity.
Bibliography:http://dx.doi.org/10.1002/anie.201005173
We kindly acknowledge the NRSC-C for financial support, Dr. T. Gadzikwa for fruitful discussions, and R. Bellini and Dr. M. Pilar del Rio Varea for assistance with the high-pressure and low-temperature NMR experiments.
istex:3413FA5F5891B1EBFBB24742BE030B56EE0E7A75
ArticleID:ANIE201005173
ark:/67375/WNG-8R9990Q8-N
NRSC-C
We kindly acknowledge the NRSC‐C for financial support, Dr. T. Gadzikwa for fruitful discussions, and R. Bellini and Dr. M. Pilar del Rio Varea for assistance with the high‐pressure and low‐temperature NMR experiments.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201005173