Visual field deficits after epilepsy surgery: a new quantitative scoring method

• Published in: Acta neurochirurgica Vol. 160; no. 7; pp. 1325 - 1336
• Main Authors: van Lanen, Rick H. G. J., Hoeberigs, M. C., Bauer, N. J. C., Haeren, R. H. L., Hoogland, G., Colon, A., Piersma, C., Dings, J. T. A., Schijns, O. E. M. G.
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.07.2018; Springer Nature B.V
• Subjects: Adult; Anterior Temporal Lobectomy - adverse effects; Drug resistance; Drug Resistant Epilepsy - surgery; Epilepsy; Epilepsy, Temporal Lobe - surgery; Feasibility studies; Female; Humans; Interventional Radiology; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Middle Aged; Minimally Invasive Surgery; Neurology; Neuroradiology; Neurosurgery; Patients; Postoperative Complications - diagnosis; Surgery; Surgical Orthopedics; Technical Note - Functional Neurosurgery - Epilepsy; Temporal lobe; Vision Disorders - diagnosis; Vision Disorders - etiology; Visual field; Visual Field Tests - methods; Visual Fields; Quadrantanopia; Perimetry; Epilepsy; Temporal lobectomy; Visual field deficits
• ISSN: 0001-6268; 0942-0940
• DOI: 10.1007/s00701-018-3525-9

Background Anterior temporal lobectomy (ATL) as a treatment for drug-resistant temporal lobe epilepsy (TLE) frequently causes visual field deficits (VFDs). Reported VFD encompasses homonymous contralateral upper quadrantanopia. Its reported incidence ranges from 15 to 90%. To date, a quantitative method to evaluate postoperative VFD in static perimetry is not available. A method to quantify postoperative VFD, which allows for comparison between groups of patients, was developed. Methods Fifty-five patients with drug-resistant TLE, who underwent ATL with pre- and postoperative perimetry, were included. Temporal lobe resection length was measured on postoperative MRI. Percentage VFD was calculated for the total visual field, contralateral upper quadrant, or other three quadrants combined. Results Patients were divided into groups by resection size (< 45 and ≥ 45 mm) and side of surgery (right and left). We found significant higher VFD in the ≥ 45 vs. < 45 mm group (2.3 ± 4.4 vs. 0.7 ± 2.4%, p  = 0.04) for right-sided ATL. Comparing VFD in both eyes, we found more VFD in the right vs. left eye following left-sided ATL (14.5 ± 9.8 vs. 12.9 ± 8.3%, p  = 0.03). We also demonstrated significantly more VFD in the < 45 mm group for left- vs. right-sided surgery (6.7 ± 6.7 vs. 13.1 ± 7.0%, p  = 0.016). A significant quantitative correlation between VFD and resection size for right-sided ATL was shown ( r  = 0.52, p  < 0.01). Conclusions We developed a new quantitative scoring method for the assessment of postoperative visual field deficits after temporal lobe epilepsy surgery and assessed its feasibility for clinical use. A significant correlation between VFD and resection size for right-sided ATL was confirmed.