Core-shell of FePt@SiO2-Au magnetic nanoparticles for rapid SERS detection

• Published in: Nanoscale research letters Vol. 10; no. 1; p. 412
• Main Authors: Hardiansyah, Andri, Chen, An-Yu, Liao, Hung-Liang, Yang, Ming-Chien, Liu, Ting-Yu, Chan, Tzu-Yi, Tsou, Hui-Ming, Kuo, Chih-Yu, Wang, Juen-Kai, Wang, Yuh-Lin
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2015; Springer Nature B.V
• Subjects: Adenine; Bacteria; Biomolecules; Chemistry and Materials Science; Core-shell particles; Core-shell structure; EMN Meeting; Gold; Gram-positive bacteria; Immobilization; Intermetallic compounds; Iron compounds; Magnetic fields; Magnetic separation; Materials Science; Microorganisms; Molecular Medicine; Nano Express; Nanochemistry; Nanoparticles; Nanoscale Science and Technology; Nanotechnology; Nanotechnology and Microengineering; Photoelectron spectroscopy; Photoelectrons; Platinum compounds; Raman spectra; Raman spectroscopy; Silica; Silicon dioxide; Sol-gel processes; Spectrum analysis; Transmission electron microscopy; X ray photoelectron spectroscopy; X-ray spectroscopy; Zeta potential; Core-shell nanoparticles; Surface-enhanced Raman scattering; Magnetic separation; Bio-detection
• ISSN: 1931-7573; 1556-276X
• DOI: 10.1186/s11671-015-1111-0

In this study, multifunctional hybrid nanoparticles composed of iron platinum (FePt), silica (SiO 2 ), and gold nanoparticles (AuNPs) had been developed for surface-enhanced Raman scattering (SERS) application. Core-shell structure of SiO 2 and FePt nanoparticles (FePt@SiO 2 ) was fabricated through sol-gel process and then immobilized gold nanoparticles onto the surface of FePt@SiO 2 , which displays huge Raman enhancement effect and magnetic separation capability. The resulting core-shell nanoparticles were subject to evaluation by transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDX), zeta potential measurement, and X-ray photoelectron spectroscopy (XPS). TEM observation revealed that the particle size of resultant nanoparticles displayed spherical structure with the size ~30 nm and further proved the successful immobilization of Au onto the surface of FePt@SiO 2 . Zeta potential measurement exhibited the successful reaction between FePt@SiO 2 and AuNPs. The rapid SERS detection and identification of small biomolecules (adenine) and microorganisms (gram-positive bacteria, Staphylococcus aureus ) was conducted through Raman spectroscopy. In summary, the novel core-shell magnetic nanoparticles could be anticipated to apply in the rapid magnetic separation under the external magnetic field due to the core of the FePt superparamagnetic nanoparticles and label-free SERS bio-sensing of biomolecules and bacteria.