Precision wearable accelerometer contact microphones for longitudinal monitoring of mechano-acoustic cardiopulmonary signals

• Published in: NPJ digital medicine Vol. 3; no. 1; pp. 19 - 8
• Main Authors: Gupta, Pranav, Moghimi, Mohammad J., Jeong, Yaesuk, Gupta, Divya, Inan, Omer T., Ayazi, Farrokh
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 12.02.2020; Nature Publishing Group; Nature Portfolio
• Subjects: 639/166/985; 639/166/987; 692/700; Accelerometers; Acoustics; Biomedicine; Biotechnology; Digital technology; Health informatics; Heart; Medicine; Medicine & Public Health; Sensors; Wearable computers; Electrical and electronic engineering; Health care; Biomedical engineering
• ISSN: 2398-6352; 2398-6352
• DOI: 10.1038/s41746-020-0225-7

Mechano-acoustic signals emanating from the heart and lungs contain valuable information about the cardiopulmonary system. Unobtrusive wearable sensors capable of monitoring these signals longitudinally can detect early pathological signatures and titrate care accordingly. Here, we present a wearable, hermetically-sealed high-precision vibration sensor that combines the characteristics of an accelerometer and a contact microphone to acquire wideband mechano-acoustic physiological signals, and enable simultaneous monitoring of multiple health factors associated with the cardiopulmonary system including heart and respiratory rate, heart sounds, lung sounds, and body motion and position of an individual. The encapsulated accelerometer contact microphone (ACM) utilizes nano-gap transducers to achieve extraordinary sensitivity in a wide bandwidth (DC-12 kHz) with high dynamic range. The sensors were used to obtain health factors of six control subjects with varying body mass index, and their feasibility in detection of weak mechano-acoustic signals such as pathological heart sounds and shallow breathing patterns is evaluated on patients with preexisting conditions.