Vapoenucleation of the prostate using a high-power thulium laser: a one-year follow-up study

• Published in: BMC urology Vol. 15; no. 1; p. 40
• Main Authors: Chang, Ching-Hsin, Lin, Tzu-Ping, Chang, Yen-Hwa, Huang, William J S, Lin, Alex T L, Chen, Kuang-Kuo
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.05.2015; BioMed Central
• Subjects: Age Factors; Aged; Aged, 80 and over; Analysis; Follow-Up Studies; Humans; Laser Therapy - methods; Lasers in medicine; Lasers, Solid-State - therapeutic use; Male; Prospective Studies; Prostatic Hyperplasia - complications; Prostatic Hyperplasia - diagnosis; Prostatic Hyperplasia - surgery; Risk Assessment; Severity of Illness Index; Sex Factors; Thulium; Time Factors; Transurethral Resection of Prostate - methods; Treatment Outcome; Urinary Bladder Neck Obstruction - etiology; Urinary Bladder Neck Obstruction - physiopathology; Urinary Bladder Neck Obstruction - surgery; Urinary Retention - etiology; Urinary Retention - physiopathology; Urinary Retention - surgery
• ISSN: 1471-2490; 1471-2490
• DOI: 10.1186/s12894-015-0032-7

Prostate vaporization and enucleation is a novel treatment option for bladder outlet obstruction caused by benign prostate enlargement. This surgical technique, however, has not yet been standardized. We present our findings of using a high-power thulium laser to accomplish vapoenucleation of the prostate (ThuVEP). We prospectively collected and analyzed data from 29 patients who underwent ThuVEP between August 2010 and May 2012. The control group included 30 patients who underwent traditional transurethral resection of the prostate (TURP). Operative variables, patient profiles, preoperative and postoperative urine flow rates, prostate volume (measured using transrectal ultrasonography), and the international prostate symptom score (IPSS) were recorded and analyzed using a two-tailed Student's t-test and analysis of variance. The ages (mean ± SD) of the patients were 76.1 ± 9.4 and 72.6 ± 7.4 years (p = 0.28) in the ThuVEP and TURP groups, respectively. The average urinary flow rates before and 12 months after the operation (volume/maximum flow/average flow) were 243.3/10.5/5.0 and 302.8/17.6/9.4 (in mL, mL/s, mL/s, respectively) in the ThuVEP group and 247.2/10.8/4.6 and 369.9/20.8/12.0, respectively, in the TURP group. Preoperative and postoperative IPSSs were 17.1 ± 5.0 and 6.5 ± 3.8, respectively, in the ThuVEP group and 18.2 ± 4.5 and 6.2 ± 3.3, respectively, in the TURP group. The mean ratio of the estimated postoperative residual prostate volume to the preoperative total volume was 0.47 (p = 0.449) in both groups. The overall complication rate was 20.7% in the ThuVEP group and 30.0% in the TURP group. One year of follow-up showed that ThuVEP and TURP effectively alleviated subjective and objective voiding symptoms with a low rate of complications. Thus, vapoenucleation using a high-power laser is feasible in elderly patients. ISRCTN registry with study ID ISRCTN52339705 . Date assigned: 06/03/2015.