Depression, anxiety, and cardiac morbidity outcomes after coronary artery bypass surgery： a contemporary and practical review

• Published in: Journal of geriatric cardiology : JGC Vol. 9; no. 2; pp. 197 - 208
• Main Authors: Phillip, J Tully, Robert, A Baker
• Format: Journal Article
• Language: English
• Published: China 1Department of Surgery, Flinders Medical Centre and Flinders University of South Australia, 3 Flinders Drive, Bedford Park, SA 5042, Australia 01.06.2012; School of Psychology,University of Adelaide Hughes Building, North Terrace, Adelaide, SA 5005, Australia; Heart Failure Self Management Pr%Department of Surgery, Flinders Medical Centre and Flinders University of South Australia, 3 Flinders Drive, Bedford Park, SA 5042, Australia; Discipline of Psychiatry, The University of Adelaide, Eleanor Harold Building, Frome Road, Adelaide, SA 5005, Australia; Science Press
• Subjects: Review; 冠状动脉; 发病率; 心脏; 手术; 抑郁症; 搭桥; 焦虑; 随机对照试验; Depression; Anxiety; Coronary artery bypass; Coronary artery disease; Antidepressive agents; Depressive disorder
• ISSN: 1671-5411
• DOI: 10.3724/sp.j.1263.2011.12221

Research to date indicates that the number of coronary artery bypass graft （CABG） surgery patients affected by depression （i.e., major, minor, dysthymia） approximates between 30% and 40% of all cases. A longstanding empirical interest on psychosocial factors in CABG surgery patients highlights an association with increased risk of morbidity in the short and longer term. Recent evidence suggests that both depression and anxiety increase the risk for mortality and morbidity after CABG surgery independent of medical factors, although the behavioral and biological mechanisms are poorly understood. Though neither depression nor anxiety seem to markedly affect neuropsy- chological dysfunction, depression confers a risk for incident delirium. Following a comprehensive overview of recent literature, practical advice is described for clinicians taking into consideration possible screening aids to improve recognition of anxiety and depression among CABG surgery patients. An overview of contemporary interventions and randomized, controlled trials are described, along with suggestions for future CABG surgery research.